The following represents disclosure information provided by authors of this abstract. The program committee has reviewed all presenting author disclosure reports, identified potential conflicts of interest, and implemented strategies to manage those areas of conflict, where appropriate. All relationships are considered compensated. Relationships are self-held unless otherwise noted. I = Immediate Family Member, Inst = My Institution
 
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Employment - MedImmune
Stock and Other Ownership Interests - AstraZeneca
Travel, Accommodations, Expenses - AstraZeneca
Safety, efficacy and pharmacodynamics (PD) of MEDI9447 (oleclumab) alone or in combination with durvalumab in advanced colorectal cancer (CRC) or pancreatic cancer (panc).
 
Michael J. Overman
Consulting or Advisory Role - Bristol-Myers Squibb; Merrimack; Roche/Genentech
Research Funding - Amgen; Bristol-Myers Squibb; Celgene; MedImmune; Merck; Roche
 
Patricia LoRusso
Leadership - Agios; Five Prime Therapeutics; Halozyme; Roche/Genentech
Honoraria - Genentech/Roche
Consulting or Advisory Role - Alexion Pharmaceuticals; ARIAD; CytomX Therapeutics; Genentech; Genentech; Genmab; Glenmark; Ignyta; Menarini; Novartis; Omniox; Takeda
Research Funding - Alexion Pharmaceuticals; Boehringer Ingelheim; Genentech (Inst); Immunogen (Inst); Merrimack (Inst); Novartis (Inst); Pfizer; Taiho Pharmaceutical (Inst); Tensha Therapeutics (Inst)
Travel, Accommodations, Expenses - Alexion Pharmaceuticals; Genentech/Roche
 
John H. Strickler
Consulting or Advisory Role - Amgen; Bayer; Celgene; Chugai/Roche; Genentech/Roche
Research Funding - Abbvie (Inst); Cascadian Therapeutics (Inst); Exelixis (Inst); Gilead Sciences (Inst); Leap Therapeutics; Macrogenics; MedImmune (Inst); OncoMed (Inst); Regeneron (Inst); Roche/Genentech (Inst); Sanofi (Inst); Seagen
 
Sandip Pravin Patel
Consulting or Advisory Role - Lilly; Novartis
Speakers' Bureau - Boehringer Ingelheim; Merck
Research Funding - Bristol-Myers Squibb (Inst); Incyte (Inst); Lilly (Inst); MedImmune (Inst); Pfizer (Inst); Roche/Genentech (Inst); Xcovery (Inst)
 
Stephen John Clarke
Consulting or Advisory Role - AstraZeneca/MedImmune; AstraZeneca/MedImmune; Bayer; Ipsen; Merck
Speakers' Bureau - Merck; Novartis/Ipsen
 
Anne M. Noonan
Consulting or Advisory Role - Helsinn Healthcare
 
Thiru Prasanna
Travel, Accommodations, Expenses - Amgen; Bristol-Myers Squibb
 
Manik A. Amin
Consulting or Advisory Role - AstraZeneca (I); TERUMO (I)
 
John J. Nemunaitis
Employment - Gradalis; US Oncology (I)
Leadership - Gradalis; Symvivo
Stock and Other Ownership Interests - Gradalis
Honoraria - Amgen; AstraZeneca
Consulting or Advisory Role - Amgen; AstraZeneca; Symvivo
Speakers' Bureau - Amgen; AstraZeneca
Research Funding - Gradalis
Patents, Royalties, Other Intellectual Property - Gradalis
Expert Testimony - Foundation Medicine
Travel, Accommodations, Expenses - Amgen; AstraZeneca; Gradalis; Symvivo
 
Jayesh Desai
Consulting or Advisory Role - Amgen; BeiGene; Bionomics; Eisai; Lilly; Novartis
Research Funding - Bionomics (Inst); GlaxoSmithKline (Inst); Novartis (Inst); Roche (Inst)
 
Kenneth John O'Byrne
Honoraria - AstraZeneca; Bristol-Myers Squibb; Genentech; MSD; Novartis; Pfizer; Roche; Teva
Consulting or Advisory Role - AstraZeneca; Bristol-Myers Squibb; Genentech; MSD; Novartis; Pfizer; Roche; Teva
Speakers' Bureau - AstraZeneca; Bristol-Myers Squibb; MSD; Pfizer; Roche
Patents, Royalties, Other Intellectual Property - Queensland University of Technology (Inst)
Travel, Accommodations, Expenses - AstraZeneca; Bristol-Myers Squibb; MSD; Roche
 
Thomas J. George
Consulting or Advisory Role - Bayer; Merck
Research Funding - AstraZeneca/MedImmune (Inst); Bayer (Inst); Bristol-Myers Squibb (Inst); Incyte (Inst); Lilly (Inst); Merck (Inst); Pharmacyclics (Inst); Tesaro (Inst)
 
Judson Englert
Employment - MedImmune
Stock and Other Ownership Interests - AstraZeneca
Patents, Royalties, Other Intellectual Property - Johns Hopkins University (Inst)
 
Dewei She
Employment - MedImmune
Stock and Other Ownership Interests - AstraZeneca
 
Zachary A. Cooper
No Relationships to Disclose
 
Yuling Wu
Employment - MedImmune
Stock and Other Ownership Interests - AstraZeneca
 
Anis Khan
Employment - MedImmune
Stock and Other Ownership Interests - AstraZeneca
 
Rakesh Kumar
Employment - MedImmune
Stock and Other Ownership Interests - AstraZeneca
Patents, Royalties, Other Intellectual Property - GlaxoSmithKline (Inst)
 
Johanna C. Bendell
Research Funding - Abbott/AbbVie (Inst); Agios (Inst); Apexigen (Inst); ARMO BioSciences (Inst); Array BioPharma (Inst); AstraZeneca/MedImmune (Inst); Bayer (Inst); Blueprint Medicines (Inst); Boehringer Ingelheim (Inst); Boston Biomedical (Inst); Bristol-Myers Squibb (Inst); Calithera Biosciences (Inst); Celgene (Inst); Celldex (Inst); CytomX Therapeutics (Inst); Daiichi Sankyo (Inst); Eisai (Inst); EMD Serono (Inst); EMD Serono (Inst); Evelo Therapeutics (Inst); Five Prime Therapeutics (Inst); FORMA Therapeutics (Inst); Forty Seven (Inst); Forty Seven (Inst); Genentech/Roche (Inst); Gilead Sciences (Inst); GlaxoSmithKline (Inst); Gritstone Bio (Inst); Incyte (Inst); Ipsen (Inst); Kolltan Pharmaceuticals (Inst); Leap Therapeutics (Inst); Lilly (Inst); Macrogenics (Inst); Marshall Edwards (Inst); Merck (Inst); Merrimack (Inst); Mersana (Inst); Merus (Inst); Nektar (Inst); Novartis (Inst); Oncogenex (Inst); OncoMed (Inst); Onyx (Inst); Pieris Pharmaceuticals (Inst); Sanofi (Inst); Stem CentRx (Inst); SynDevRx (Inst); Taiho Pharmaceutical (Inst); Takeda (Inst); Tarveda Therapeutics (Inst); TG Therapeutics (Inst); Tyrogenex (Inst)