The following represents disclosure information provided by authors of this abstract. The program committee has reviewed all presenting author disclosure reports, identified potential conflicts of interest, and implemented strategies to manage those areas of conflict, where appropriate. All relationships are considered compensated. Relationships are self-held unless otherwise noted. I = Immediate Family Member, Inst = My Institution
 
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Analysis of the kinetics and effects of vemurafenib (V) + cobimetinib (C) on intratumoral and host immunity in patients (pts) with BRAFV600 mutant melanoma (BRAFmM): Implications for combination with immunotherapy.
 
Suthee Rapisuwon
Research Funding - Bristol-Myers Squibb
 
Craig L. Slingluff
Consulting or Advisory Role - Immatics (Inst); Polynoma (Inst)
Research Funding - 3M (Inst); GlaxoSmithKline (Inst); Merck Sharp & Dohme (Inst); Theraclion (Inst)
Patents, Royalties, Other Intellectual Property - Licensing and Ventures Group of the University of Virginia
 
Jennifer Ann Wargo
Leadership - Microbiome DX
Honoraria - Bristol-Myers Squibb; Dava Oncology; Genentech; GlaxoSmithKline; Illumina; Novartis
Consulting or Advisory Role - Bristol-Myers Squibb; Dava Oncology; Genentech; GlaxoSmithKline; Illumina; Novartis
Speakers' Bureau - Genentech; Novartis
Research Funding - Bristol-Myers Squibb (Inst); Genentech (Inst); GlaxoSmithKline (Inst); Novartis (Inst)
Patents, Royalties, Other Intellectual Property - Patent submitted regarding the role of the microbiome in response to immune checkpoint blockade
Travel, Accommodations, Expenses - Bristol-Myers Squibb; Dava Oncology; Genentech; GlaxoSmithKline; Illumina; Novartis
 
Ryan J. Sullivan
Honoraria - Roche/Genentech
Consulting or Advisory Role - ACI Clinical; Amgen; Array BioPharma; Biodesix; BiolineRx; Merck; Novartis; Takeda; WorldCare Clinical, LLC
Research Funding - Aeglea Biotherapeutics (Inst); Amgen (Inst); BioMed Valley Discoveries (Inst); Deciphera (Inst); Lilly (Inst); Merck (Inst); Moderna Therapeutics (Inst); Roche/Genentech (Inst); Sanofi (Inst)
Other Relationship - Boehringer Ingelheim
 
Benjamin Izar
No Relationships to Disclose
 
Ileana S Maudlin
No Relationships to Disclose
 
Geoffrey Thomas Gibney
Consulting or Advisory Role - Genentech/Roche; Genentech/Roche; Incyte; Newlink Genetics; Novartis
Speakers' Bureau - Genentech/Roche; Merck
 
Waddah B. Al-Refaie
No Relationships to Disclose
 
Bridget Haley
No Relationships to Disclose
 
Michael B. Atkins
Honoraria - Bristol-Myers Squibb
Consulting or Advisory Role - Acceleron Pharma; Aduro Biotech; Agenus; Alexion Pharmaceuticals; Argos Therapeutics; Array BioPharma; AstraZeneca/MedImmune; Boehringer Ingelheim; Bristol-Myers Squibb; Celldex; Eisai; Exelixis; Genentech; Glactone Pharma; Idera; Merck; Nektar; Novartis; Peleton; Pfizer; X4 Pharma