The following represents disclosure information provided by authors of this abstract. The program committee has reviewed all presenting author disclosure reports, identified potential conflicts of interest, and implemented strategies to manage those areas of conflict, where appropriate. All relationships are considered compensated. Relationships are self-held unless otherwise noted. I = Immediate Family Member, Inst = My Institution
 
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CB-839, panitumumab, and irinotecan in RAS wildtype (WT) metastatic colorectal cancer (mCRC): Phase I results.
 
Kristen Keon Ciombor
Consulting or Advisory Role - Bayer
Research Funding - Amgen (Inst); Array BioPharma (Inst); Bayer (Inst); Boehringer Ingelheim (Inst); Boston Biomedical (Inst); Bristol-Myers Squibb (Inst); Bristol-Myers Squibb (Inst); Daiichi Sankyo (Inst); Incyte (Inst); Incyte (Inst); MedImmune (Inst); Merck (Inst); Novartis (Inst); Nucana (Inst); Onyx (Inst); Pfizer (Inst); Sanofi (Inst)
 
Jennifer Whisenant
Research Funding - EMD Serono (Inst)
Patents, Royalties, Other Intellectual Property - I am listed as an inventor on a patent licensed to Anasys Instruments.
 
Dana Backlund Cardin
Consulting or Advisory Role - Merrimack; Rafael Pharmaceuticals
Research Funding - Advaxis (Inst); Array BioPharma (Inst); Bristol-Myers Squibb (Inst); Celgene (Inst); EMD Serono (Inst); Incyte (Inst); Oncolytics (Inst); Roche (Inst); Synta (Inst)
 
Laura Williams Goff
Consulting or Advisory Role - Bayer/Onyx; Eisai; Lilly; Newlink Genetics
Research Funding - Agios; ArQule; Astellas Pharma; Bristol-Myers Squibb; H3 Biomedicine; Incyte; Leap Therapeutics; Lilly; Onyx; Pfizer; Sun Pharma
 
Satya Das
Honoraria - Targeted Oncology
 
Michael Schulte
No Relationships to Disclose
 
Allison Cohen
No Relationships to Disclose
 
Robert J. Coffey
No Relationships to Disclose
 
Gregory Dan Ayers
Research Funding - Karyopharm Therapeutics (Inst)
Travel, Accommodations, Expenses - Incyte
 
Rachel Krumsick
No Relationships to Disclose
 
Susan Demo
Employment - Calithera Biosciences
 
Sam H. Whiting
Employment - Calithera Biosciences
 
H. Charles Manning
No Relationships to Disclose
 
Jordan Berlin
Honoraria - genentech; Nestle health science
Consulting or Advisory Role - Abbvie; Arno Therapeutics; AstraZeneca; BeiGene; Celgene; Cornerstone Pharmaceuticals; Eisai; EMD Serono; ERYTECH Pharma; Exelixis; Five Prime Therapeutics; Genentech/Roche; Gritstone Bio; Karyopharm Therapeutics; Symphogen
Research Funding - Bayer (Inst); BeiGene (Inst); EMD Serono (Inst); Five Prime Therapeutics (Inst); Genentech/Roche (Inst); Gilead Sciences (Inst); Immunomedics (Inst); Incyte (Inst); Karyopharm Therapeutics (Inst); Loxo (Inst); Pharmacyclics (Inst); symphogen (Inst); Taiho Pharmaceutical (Inst)
Travel, Accommodations, Expenses - Abbvie; EMD Serono; Genentech/Roche; Nestle health science
Other Relationship - AstraZeneca