The following represents disclosure information provided by authors of this abstract. The program committee has reviewed all presenting author disclosure reports, identified potential conflicts of interest, and implemented strategies to manage those areas of conflict, where appropriate. All relationships are considered compensated. Relationships are self-held unless otherwise noted. I = Immediate Family Member, Inst = My Institution
 
Open Payments is a public database containing information reported by companies about payments made to US-licensed physicians (Open Payments)
 
 
Employment - Caris Life Sciences
Leadership - Caris Life Sciences
Stock and Other Ownership Interests - Caris Life Sciences; OncoCyte
Consulting or Advisory Role - Lilly; Merck

Gene-specific features (MLH1, MSH2, MSH6, PMS2) of mismatch repair (MMR) protein expression and somatic mutations (muts), microsatellite instability (MSI) and tumor mutational burden (TMB) in MSI-H and MMR-mutated tumor genomic profiles (TGPs).
 
Michael J. Hall
Patents, Royalties, Other Intellectual Property - I share a patent with several Fox Chase investigators for a novel method to investigate hereditary CRC genes (Inst)
Travel, Accommodations, Expenses - Foundation Medicine
Other Relationship - Caris Life Sciences; Foundation Medicine; Invitae; Myriad Genetics
 
Joseph Nicholas Bodor
No Relationships to Disclose
 
Joanne Xiu
Employment - Caris Life Sciences
 
Rebecca Feldman
Employment - Caris Life Sciences
 
Axel Grothey
Consulting or Advisory Role - Amgen (Inst); Array BioPharma (Inst); Bayer (Inst); Boston Biomedical (Inst); Bristol-Myers Squibb (Inst); Genentech/Roche (Inst); Guardant Health (Inst); Lilly (Inst)
Research Funding - Bayer (Inst); Boehringer Ingelheim (Inst); Boston Biomedical (Inst); Eisai (Inst); Genentech/Roche (Inst); Lilly (Inst); Pfizer (Inst); Sanofi (Inst)
Travel, Accommodations, Expenses - Amgen; Bayer; Boehringer Ingelheim; Boston Biomedical; Bristol-Myers Squibb; Genentech/Roche; Merck Sharp & Dohme
 
Richard M. Goldberg
Consulting or Advisory Role - Merck; Merck KGaA; Taiho Pharmaceutical
Research Funding - Bristol-Myers Squibb
Travel, Accommodations, Expenses - Merck; Merck KGaA
 
William Mills Worrilow
No Relationships to Disclose
 
Jimmy J. Hwang
Consulting or Advisory Role - Amgen; Bayer; Boehringer Ingelheim; Bristol-Myers Squibb; Genentech/Roche; Ipsen; Lilly; Taiho Pharmaceutical
Speakers' Bureau - Amgen; Bristol-Myers Squibb; Celgene; Genentech/Roche; Ipsen
 
Edward S. Kim
Honoraria - AstraZeneca; Boehringer Ingelheim; Celgene; Lilly; Merck; Pfizer
Consulting or Advisory Role - AstraZeneca; Boehringer Ingelheim; Celgene; Lilly; Merck; Pfizer
Research Funding - Boehringer Ingelheim; Genentech/Roche; Ignyta; Lilly; Merck
Travel, Accommodations, Expenses - AstraZeneca; Boehringer Ingelheim; Celgene; Lilly
 
Heinz-Josef Lenz
Honoraria - Bayer; Boehringer Ingelheim; Merck Serono; Roche
Consulting or Advisory Role - Bayer; Merck Serono; Pfizer; Roche
Travel, Accommodations, Expenses - Bayer; Merck Serono; Roche
 
Derek Raghavan
Consulting or Advisory Role - Caris Life Sciences (Inst); Gerson Lehrman Group
 
Anthony Frank Shields
Employment - Benchling (I)
Stock and Other Ownership Interests - Benchling (I)
Consulting or Advisory Role - Bayer; Bristol-Myers Squibb; Endocyte; GE Healthcare; Merck; Merrimack; Personal Genome Diagnostics; Siemens Healthcare Diagnostics; Taiho Pharmaceutical
Speakers' Bureau - GE Healthcare
Research Funding - Bayer; Boehringer Ingelheim; Bristol-Myers Squibb; Caris Life Sciences; Eisai; H3 Biomedicine; Inovio Pharmaceuticals; Karyopharm Therapeutics; Merrimack; Novartis; OncoMed; Plexxikon; Taiho Pharmaceutical
Travel, Accommodations, Expenses - Caris Life Sciences; Endocyte; GE Healthcare; Merrimack
 
John Marshall
Employment - Caris Life Sciences
Honoraria - Amgen; Bayer/Onyx; Caris Life Sciences; Celgene; Genentech/Roche; Taiho Pharmaceutical
Consulting or Advisory Role - Amgen; Bayer/Onyx; Caris Life Sciences; Celgene; Genentech/Roche; Taiho Pharmaceutical
Speakers' Bureau - Amgen; Bayer/Onyx; Celgene; Genentech/Roche; Taiho Pharmaceutical
Research Funding - Amgen (Inst); Bayer/Onyx (Inst); Boehringer Ingelheim (Inst); Genentech/Roche (Inst); MedImmune (Inst); Pfizer (Inst)
 
W. Michael Korn
No Relationships to Disclose
 
Mohamed E. Salem
Consulting or Advisory Role - Genentech/Roche; Taiho Pharmaceutical
Speakers' Bureau - Genentech/Roche; Taiho Pharmaceutical
Research Funding - Bayer (Inst); Taiho Pharmaceutical (Inst)