The following represents disclosure information provided by authors of this abstract. The program committee has reviewed all presenting author disclosure reports, identified potential conflicts of interest, and implemented strategies to manage those areas of conflict, where appropriate. All relationships are considered compensated. Relationships are self-held unless otherwise noted. I = Immediate Family Member, Inst = My Institution
 
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Eltanexor (KPT-8602), a second-generation selective inhibitor of nuclear export (SINE) compound, in patients with metastatic castration-resistant prostate cancer (mCRPC).
 
Jingsong Zhang
Honoraria - AstraZeneca/MedImmune; Bayer; Sanofi
Consulting or Advisory Role - AstraZeneca/MedImmune; Bayer; Sanofi
Speakers' Bureau - AstraZeneca/MedImmune; Sanofi
Research Funding - Astellas Medivation (Inst); AstraZeneca/MedImmune (Inst); Bayer (Inst)
 
David D. Chism
Stock and Other Ownership Interests - Biogen (I)
Travel, Accommodations, Expenses - Lilly
 
Scott T. Tagawa
Consulting or Advisory Role - Abbvie; Astellas Pharma; Bayer; Dendreon; Endocyte; Genentech; Immunomedics; Janssen; Karyopharm Therapeutics; Medivation; Sanofi; Tolmar
Research Funding - Abbvie (Inst); Amgen (Inst); Astellas Pharma (Inst); AstraZeneca (Inst); AVEO (Inst); Bayer (Inst); Boehringer Ingelheim (Inst); Bristol-Myers Squibb (Inst); Clovis Oncology (Inst); Dendreon (Inst); Endocyte (Inst); Exelixis (Inst); Genentech (Inst); Immunomedics (Inst); Inovio Pharmaceuticals (Inst); Janssen (Inst); Karyopharm Therapeutics (Inst); Lilly (Inst); Medivation (Inst); Merck (Inst); Millennium (Inst); Newlink Genetics (Inst); Novartis (Inst); Progenics (Inst); Rexahn Pharmaceuticals (Inst); Sanofi (Inst); Stem CentRx (Inst)
Travel, Accommodations, Expenses - Immunomedics; Sanofi
 
Paul Monk
Consulting or Advisory Role - Bayer; Lilly
Speakers' Bureau - Dendreon; Sanofi
Research Funding - Prometheus
Travel, Accommodations, Expenses - Lilly
 
Robert S. Alter
Consulting or Advisory Role - Pfizer/EMD Serono
Speakers' Bureau - Astellas Pharma; Bristol-Myers Squibb; Genentech; Janssen Oncology; Merck; Pfizer
 
William Reichman
Employment - ARIAD; Karyopharm Therapeutics; Takeda
Stock and Other Ownership Interests - ARIAD; Karyopharm Therapeutics
 
William Senapedis
Employment - Karyopharm Therapeutics
Stock and Other Ownership Interests - Karyopharm Therapeutics
Research Funding - Karyopharm Therapeutics
Patents, Royalties, Other Intellectual Property - Several patents at Karyopharm Therapeutics (Inst)
Travel, Accommodations, Expenses - Karyopharm Therapeutics
 
Erkan Baloglu
Employment - Bristol-Myers Squibb (I); Karyopharm Therapeutics
Stock and Other Ownership Interests - Bristol-Myers Squibb (I); Karyopharm Therapeutics
Patents, Royalties, Other Intellectual Property - Karyopharm Therapeutics
 
Sharon Shacham
Employment - Karyopharm Therapeutics; Karyopharm Therapeutics (I)
Leadership - Karyopharm Therapeutics; Karyopharm Therapeutics (I)
Stock and Other Ownership Interests - Karyopharm Therapeutics; Karyopharm Therapeutics (I)
Patents, Royalties, Other Intellectual Property - Karyopharm Therapeutics; Karyopharm Therapeutics (I)
 
Michael G. Kauffman
Employment - Karyopharm Therapeutics; Karyopharm Therapeutics (I)
Leadership - Karyopharm Therapeutics; Karyopharm Therapeutics (I)
Stock and Other Ownership Interests - Karyopharm Therapeutics; Karyopharm Therapeutics (I)
Patents, Royalties, Other Intellectual Property - Karyopharm Therapeutics; Karyopharm Therapeutics (I)