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| Lessons learned from the metastatic castration-resistant prostate cancer phase I trial of EPI-506, a first-generation androgen receptor N-terminal domain inhibitor. | 
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| No Relationships to Disclose | 
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| Employment - Cleave Biosciences; ESSA | 
| Stock and Other Ownership Interests  - Cleave Biosciences; ESSA | 
| Patents, Royalties, Other Intellectual Property - Cleave Biosciences; ESSA | 
| Travel, Accommodations, Expenses - Cleave Biosciences; ESSA | 
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| Patents, Royalties, Other Intellectual Property - ESSA | 
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| Stock and Other Ownership Interests  - ESSA | 
| Patents, Royalties, Other Intellectual Property - ESSA | 
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| Consulting or Advisory Role - ESSA | 
| Patents, Royalties, Other Intellectual Property - ESSA | 
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| No Relationships to Disclose | 
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| Stock and Other Ownership Interests  - ESSA | 
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| Patents, Royalties, Other Intellectual Property - ESSA | 
| Travel, Accommodations, Expenses - ESSA | 
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| Stock and Other Ownership Interests  - ESSA | 
| Consulting or Advisory Role - ESSA | 
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| Patents, Royalties, Other Intellectual Property - ESSA | 
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| Stock and Other Ownership Interests  - ESSA | 
| Consulting or Advisory Role - ESSA | 
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| Patents, Royalties, Other Intellectual Property - ESSA | 
| Expert Testimony - Pfizer | 
| Travel, Accommodations, Expenses - ESSA | 
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| Stock and Other Ownership Interests  - ESSA | 
| Research Funding - ESSA (Inst) | 
| Patents, Royalties, Other Intellectual Property - ESSA | 
| Travel, Accommodations, Expenses - ESSA | 
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| Honoraria - Astellas Pharma; Bayer; Janssen; Sanofi | 
| Consulting or Advisory Role - Amgen; Astellas Pharma; Bayer; ESSA; Janssen; Lilly/ImClone; Sanofi | 
| Research Funding - Astellas Pharma (Inst); Bayer (Inst); Bristol-Myers Squibb (Inst); Janssen (Inst); Lilly/ImClone (Inst); Merck (Inst); Roche (Inst); Sanofi (Inst); Tokai Pharmaceuticals (Inst) |