The following represents disclosure information provided by authors of this abstract. The program committee has reviewed all presenting author disclosure reports, identified potential conflicts of interest, and implemented strategies to manage those areas of conflict, where appropriate. All relationships are considered compensated. Relationships are self-held unless otherwise noted. I = Immediate Family Member, Inst = My Institution
 
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Tumor mutational burden (TMB) may be a promising predictive biomarker of response to PD-1/PD-L1 targeting in MSI-H colorectal cancer.
 
Marwan Fakih
Consulting or Advisory Role - Amgen; Array BioPharma; Genentech/Roche
Speakers' Bureau - Amgen; Taiho Pharmaceutical
Research Funding - Amgen (Inst); AstraZeneca (Inst); Novartis (Inst)
 
Jaideep Singh Sandhu
No Relationships to Disclose
 
Ching Ouyang
No Relationships to Disclose
 
Ethan Sokol
No Relationships to Disclose
 
Jeffrey S. Ross
Employment - Foundation Medicine
Stock and Other Ownership Interests - Foundation Medicine
 
Vincent A. Miller
Employment - Foundation Medicine
Leadership - Foundation Medicine
Stock and Other Ownership Interests - Foundation Medicine
Consulting or Advisory Role - Revolution Medicines
Patents, Royalties, Other Intellectual Property - Receive periodic royalties related to T790M patent awarded to Memorial Sloan Kettering Cancer Center
 
Dean Lim
No Relationships to Disclose
 
Joseph Chao
Consulting or Advisory Role - AstraZeneca (Inst); Boston Biomedical; Five Prime Therapeutics; Lilly; Merck
Speakers' Bureau - Merck
Research Funding - Merck (Inst); Novonco Therapeutics (Inst)
 
Daniel V.T. Catenacci
Honoraria - Amgen; Astellas Pharma; Bristol-Myers Squibb; Five Prime Therapeutics; Foundation Medicine; Genentech/Roche; Genmab; Gritstone Bio; Guardant Health; Lilly; Merck; NantWorks; OncoPlex Diagnostics; Taiho Pharmaceutical
Consulting or Advisory Role - Amgen; Astellas Pharma; Bristol-Myers Squibb; Genentech/Roche; Lilly; Merck; Taiho Pharmaceutical
Speakers' Bureau - Foundation Medicine; Genentech; Guardant Health; Lilly; Merck; Merck
 
May Thet Cho
No Relationships to Disclose
 
Fadi S. Braiteh
Stock and Other Ownership Interests - Agios; Bristol-Myers Squibb; Clovis Oncology; Insys Therapeutics; Tesaro
Honoraria - Abbott Nutrition; Amgen; ARIAD; AstraZeneca; Bayer; Boehringer Ingelheim; Bristol-Myers Squibb; Celgene; Genentech/Roche; HERON; Incyte; Insys Therapeutics; Insys Therapeutics; Ipsen; Lexicon; Lilly; Taiho Pharmaceutical
Consulting or Advisory Role - Ambry Genetics; Amgen; AstraZeneca; Bayer; Boehringer Ingelheim; Bristol-Myers Squibb; Celgene; Clovis Oncology; Genentech/Roche; Incyte; Insys Therapeutics; Ipsen; Ipsen; Lexicon; Lilly; Merck; Merrimack; Pfizer; Regeneron; Sanofi
Speakers' Bureau - Amgen; AstraZeneca; Boehringer Ingelheim; Bristol-Myers Squibb; Celgene; Genentech/Roche; Incyte; Insys Therapeutics; Ipsen; Lilly; Merck; Merck; Merrimack; Pfizer; Taiho Pharmaceutical
Travel, Accommodations, Expenses - Amgen; AstraZeneca/MedImmune; Bayer; Bayer/Onyx; Boehringer Ingelheim; Bristol-Myers Squibb; Celgene; Clovis Oncology; Exelixis; HERON; Incyte; Insys Therapeutics; Ipsen; Lexicon; Merrimack; Novartis; Pfizer; Regeneron; Roche/Genentech; Sanofi; Taiho Pharmaceutical; Tesaro
 
Steven Brad Maron
Research Funding - Genentech
 
Leah Chase
Patents, Royalties, Other Intellectual Property - Prescient Surgical
 
Samuel Jacob Klempner
Stock and Other Ownership Interests - TP Therapeutics
Consulting or Advisory Role - Astellas Pharma; Boston Biomedical; Lilly
Speakers' Bureau - Foundation Medicine
Research Funding - Astellas Pharma (Inst); Leap Therapeutics (Inst)
Travel, Accommodations, Expenses - Lilly
 
Siraj Mahamed Ali
Employment - Foundation Medicine; Foundation Medicine
Leadership - Incysus
Stock and Other Ownership Interests - Agios; Blueprint Medicines; Exelixis; Genocea Biosciences
Patents, Royalties, Other Intellectual Property - patents via FOundation Medicine; Patents via Seres Health on microbiome stuff in non neoplastic disease (I)
 
Alexa Betzig Schrock
Employment - Foundation Medicine
Stock and Other Ownership Interests - Foundation Medicine