The following represents disclosure information provided by authors of this abstract. The program committee has reviewed all presenting author disclosure reports, identified potential conflicts of interest, and implemented strategies to manage those areas of conflict, where appropriate. All relationships are considered compensated. Relationships are self-held unless otherwise noted. I = Immediate Family Member, Inst = My Institution
 
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A phase Ia/b study of TIM-3/PD-L1 bispecific antibody in patients with advanced solid tumors.
 
Matthew David Hellmann
Stock and Other Ownership Interests - Shattuck Labs
Honoraria - AstraZeneca; Bristol-Myers Squibb
Consulting or Advisory Role - AstraZeneca/MedImmune; Bristol-Myers Squibb; Genentech; Janssen; Merck; Mirati Therapeutics; Nektar; Novartis; Shattuck Labs; Syndax
Research Funding - Bristol-Myers Squibb (Inst)
Patents, Royalties, Other Intellectual Property - A patent has been filed by Memorial Sloan Kettering (PCT/US2015/062208) for the use of tumor mutation burden for prediction of immunotherapy efficacy, and which is licensed to Personal Genome Diagnostics. (Inst)
Travel, Accommodations, Expenses - AstraZeneca; Bristol-Myers Squibb
 
Toshio Shimizu
Consulting or Advisory Role - Joint Scientific Committee Review Member; The Consortium on Harmonization of Institutional Requirements for Clinical Research
Speakers' Bureau - Boehringer Ingelheim; Chugai Pharma; Ono Pharmaceutical; Ono Pharmaceutical; Taiho Pharmaceutical
Research Funding - 3D Medicines (Inst); Bristol-Myers Squibb (Inst); Chordia Therapeutics (Inst); Daiichi Sankyo (Inst); Eisai (Inst); Five Prime Therapeutics (Inst); Lilly (Inst); Millennium (Inst); Novartis (Inst); PharmaMar (Inst); SymBio Pharmaceuticals (Inst)
Travel, Accommodations, Expenses - Millennium
 
Toshihiko Doi
Consulting or Advisory Role - Abbvie; Amgen; Bayer; Daiichi Sankyo; Kyowa Hakko Kirin; MSD; Novartis; Sumitomo Dainippon; Taiho Pharmaceutical; Takeda
Research Funding - Abbvie (Inst); Boehringer Ingelheim (Inst); Bristol-Myers Squibb (Inst); Daiichi Sankyo (Inst); Eisai (Inst); Kyowa Hakko Kirin (Inst); Lilly Japan (Inst); Merck Serono (Inst); MSD (Inst); Novartis (Inst); Pfizer (Inst); Quintiles (Inst); Sumitomo Group (Inst); Taiho Pharmaceutical (Inst)
 
F. Stephen Hodi
Employment - Dana-Farber Cancer Institute
Stock and Other Ownership Interests - Apricity Health
Consulting or Advisory Role - Aduro Biotech; Amgen; Bayer; Bristol-Myers Squibb; Celldex; EMD Serono; Genentech/Roche; Incyte; Incyte; Incyte; Merck Sharp & Dohme; Novartis; Pfizer; Sanofi; Verastem
Research Funding - bristol-myers squibb (Inst); Genentech/Roche (Inst); Merck Sharp & Dohme (Inst); novartis (Inst)
Patents, Royalties, Other Intellectual Property - Angiopoietin-2 Biomarkers Predictive of Anti-immune checkpoint response (Inst); Compositions and Methods for Identification, Assessment, Prevention, and Treatment of Melanoma using PD-L1 Isoforms; Methods of Using Pembrolizumab and Trebananib (Inst); patent pending as per institutional policy; patent pending royalties received on MICA related disorders application to institution per institutional IP policy
Travel, Accommodations, Expenses - Bristol-Myers Squibb; Novartis
Other Relationship - Bristol-Myers Squibb; Genentech/Roche
 
Sylvie Rottey
No Relationships to Disclose
 
Philippe Georges Aftimos
Honoraria - Roche; Synthon
Consulting or Advisory Role - Amcure; Amgen; Boehringer Ingelheim; Macrogenics; Novartis; Novartis; Roche
Travel, Accommodations, Expenses - Amgen; MSD Oncology; Pfizer; Roche Belgium
 
Zhuqing Tina Liu
No Relationships to Disclose
 
Nieves Velez de Mendizabal
Employment - Lilly
Stock and Other Ownership Interests - Lilly
Patents, Royalties, Other Intellectual Property - Lilly
 
Anna M. Szpurka
Employment - Lilly; Lilly; Lilly (I)
Stock and Other Ownership Interests - Lilly; Lilly (I)
Research Funding - Lilly; Lilly (I)
 
Yongzhe Piao
Employment - Lilly Japan
Stock and Other Ownership Interests - Lilly
 
Burkhard Vangerow
Employment - Lilly
Stock and Other Ownership Interests - Lilly
 
Leena Gandhi
Employment - Lilly
Stock and Other Ownership Interests - Lilly
Consulting or Advisory Role - AstraZeneca; Bristol-Myers Squibb (Inst); Ignyta; Merck (Inst); Merck Sharp & Dohme; Roche/Genentech; Syndax
Research Funding - Bristol-Myers Squibb; Merck Sharp & Dohme
 
Ching Ching Leow
Employment - Lilly
Stock and Other Ownership Interests - Lilly