The following represents disclosure information provided by authors of this abstract. The program committee has reviewed all presenting author disclosure reports, identified potential conflicts of interest, and implemented strategies to manage those areas of conflict, where appropriate. All relationships are considered compensated. Relationships are self-held unless otherwise noted. I = Immediate Family Member, Inst = My Institution
 
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S1507: Phase II study of docetaxel and trametinib in patients with G12C or non-G12C KRAS mutation positive (+) recurrent non-small cell lung cancer (NSCLC).
 
Shirish M. Gadgeel
Honoraria - AstraZeneca; Genentech/Roche
Consulting or Advisory Role - Abbvie; AstraZeneca; Bristol-Myers Squibb; Genentech/Roche; Pfizer; Takeda
Research Funding - Aeglea Biotherapeutics (Inst); ARIAD/Takeda (Inst); Astellas Pharma (Inst); Blueprint Medicines (Inst); Daiichi Sankyo (Inst); G1 Therapeutics (Inst); Genentech/Roche (Inst); Lycera (Inst); Merck; Merck (Inst); Pfizer (Inst)
Travel, Accommodations, Expenses - AstraZeneca; Genentech/Roche
 
Jieling Miao
No Relationships to Disclose
 
Jonathan W. Riess
Consulting or Advisory Role - Abbvie; Biodesix; Celgene; Loxo; Medtronic; Spectrum Pharmaceuticals; Takeda
Research Funding - AstraZeneca/MedImmune (Inst); Boehringer Ingelheim (Inst); Merck (Inst); Novartis (Inst); Spectrum Pharmaceuticals (Inst)
 
Philip C. Mack
Honoraria - Guardant Health
Consulting or Advisory Role - AstraZeneca; Guardant Health; Pfizer
Research Funding - Boehringer Ingelheim
 
Gregory James Gerstner
Employment - illinois Cancer Care
Leadership - illinois Cancer Care
Stock and Other Ownership Interests - illinois Cancer Care
Research Funding - illinois Cancer Care
 
Timothy F. Burns
Consulting or Advisory Role - Abbvie/Stemcentrx
 
Asma Taj
No Relationships to Disclose
 
Wallace L. Akerley
Honoraria - AstraZeneca
Research Funding - Bristol-Myers Squibb; Incyte; Loxo
 
Konstantin H. Dragnev
Research Funding - G1 Therapeutics (Inst); Io Therapeutics (Inst); Lilly (Inst); Merck (Inst); Novartis (Inst); PharmaMar (Inst); Roche/Genentech (Inst)
 
James Moon
No Relationships to Disclose
 
David R. Gandara
No Relationships to Disclose
 
Karen Kelly
Honoraria - Merck
Consulting or Advisory Role - Abbvie; AstraZeneca; EMD Serono; Genentech/Roche; Janssen; Lilly; Merck; Pfizer; Regeneron
Research Funding - Abbvie (Inst); Celgene (Inst); EMD Serono (Inst); Five Prime Therapeutics (Inst); Genentech (Inst); Lilly (Inst); Lycera (Inst); Regeneron (Inst); Transgene (Inst)
Patents, Royalties, Other Intellectual Property - Author Royalties for UpToDate, an evidence based, peer reviewed information resource, available via the web, desktop, and PDA.
Travel, Accommodations, Expenses - Abbvie; AstraZeneca; EMD Serono; Genentech/Roche; Lilly; Merck; Regeneron