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SOPHIA primary analysis: A phase 3 (P3) study of margetuximab (M) + chemotherapy (C) versus trastuzumab (T) + C in patients (pts) with HER2+ metastatic (met) breast cancer (MBC) after prior anti-HER2 therapies (Tx). |
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Research Funding - Daiichi Sankyo (Inst); Eisai (Inst); Genentech (Inst); Immunomedics (Inst); Lilly (Inst); Macrogenics (Inst); Merck (Inst); Novartis (Inst); OBI Pharma (Inst); Odonate Therapeutics (Inst); Pfizer (Inst); Seagen (Inst) |
Travel, Accommodations, Expenses - Amgen; Mylan; Novartis; OBI Pharma; Pfizer; Puma Biotechnology; Roche/Genentech; Sanofi |
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Consulting or Advisory Role - AstraZeneca; Eisai; Novartis; Pfizer; Roche/Genentech |
Research Funding - AstraZeneca; Pfizer |
Travel, Accommodations, Expenses - MSD Oncology; Novartis; Roche/Genentech |
Other Relationship - Roche |
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Stock and Other Ownership Interests - Odonate Therapeutics; Puma Biotechnology; Roche |
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Santiago Escriva-de-Romani |
Consulting or Advisory Role - Pierre Fabre; Roche |
Speakers' Bureau - Celgene; Eisai; Kyowa Hakko Kirin; Pierre Fabre; Roche |
Travel, Accommodations, Expenses - Daiichi Sankyo; Pierre Fabre; Roche |
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Honoraria - Amgen; Celgene; Eisai; Lilly; Novartis; Pfizer; Roche |
Consulting or Advisory Role - Amgen; Celgene; Eisai; Lilly; Novartis; Pfizer; Roche |
Speakers' Bureau - Amgen; Celgene; Eisai; Lilly; Novartis; Pfizer; Roche |
Research Funding - Eisai; Roche |
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Stock and Other Ownership Interests - MedSIR |
Honoraria - Celgene; Eisai; Novartis; Pfizer; Roche; Samsung |
Consulting or Advisory Role - AstraZeneca; Biothera; Celgene; Cellestia Biotech; Daiichi Sankyo; ERYTECH Pharma; Merus; Polyphor; Roche; Seagen |
Research Funding - ARIAD (Inst); AstraZeneca (Inst); Baxalta (Inst); Bayer (Inst); Eisai (Inst); Guardant Health (Inst); Merck Sharp & Dohme (Inst); Pfizer (Inst); Pique (Inst); Puma Biotechnology (Inst); Queen Mary university of London (Inst); Roche (Inst) |
Travel, Accommodations, Expenses - Eisai; Novartis; Pfizer; Roche |
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Travel, Accommodations, Expenses - Macrogenics |
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Research Funding - GlaxoSmithKline; Lilly; Puma Biotechnology; Roche |
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Research Funding - BMS Brazil; Roche |
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Consulting or Advisory Role - Agendia; Bayer; Celgene; Impact Biomedicines |
Speakers' Bureau - Novartis; Puma Biotechnology |
Research Funding - Agendia; Amgen; Daiichi Sankyo; Evidera; Genentech; Helsinn Healthcare; Macrogenics; Merck; Novartis; Pfizer; Puma Biotechnology; Roche; TG Therapeutics |
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No Relationships to Disclose |
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Consulting or Advisory Role - Amgen; Astellas Pharma; AstraZeneca; Celgene; Daiichi Sankyo; Eisai; GE Healthcare; Genentech; GlaxoSmithKline; Macrogenics; Merck Sharp & Dohme; Merus; Mundipharma; Mylan; Novartis; Pfizer; Pierre Fabre; Roche; Samsung Bioepis; Sanofi; Seagen; Teva |
Travel, Accommodations, Expenses - AstraZeneca; Pfizer; Roche |
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Honoraria - Ellipses Pharma |
Consulting or Advisory Role - Bristol-Myers Squibb; Foundation Medicine; Lilly; Novartis; Pfizer; Roche/Genentech; Samsung |
Speakers' Bureau - Foundation Medicine; Lilly; Novartis; Pfizer; Roche/Genentech; Samsung |
Travel, Accommodations, Expenses - Pfizer; Roche/Genentech |
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Stock and Other Ownership Interests - Amgen |
Consulting or Advisory Role - Eisai; Lilly; Macrogenics; Polyphor; Roche/Genentech |
Speakers' Bureau - Lilly; Teva |
Research Funding - Eisai (Inst); Lilly (Inst); Macrogenics (Inst); Novartis (Inst); Polyphor (Inst); Roche/Genentech (Inst) |
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Honoraria - See consulting below |
Consulting or Advisory Role - Daiichi Sankyo; Genentech/Roche; Macrogenics; Seagen |
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Stock and Other Ownership Interests - Macrogenics |
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Stock and Other Ownership Interests - Macrogenics |
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Consulting or Advisory Role - Genentech/Roche |