The following represents disclosure information provided by authors of this abstract. The program committee has reviewed all presenting author disclosure reports, identified potential conflicts of interest, and implemented strategies to manage those areas of conflict, where appropriate. All relationships are considered compensated. Relationships are self-held unless otherwise noted. I = Immediate Family Member, Inst = My Institution
 
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SGNLVA-002: Single-arm, open label phase Ib/II study of ladiratuzumab vedotin (LV) in combination with pembrolizumab for first-line treatment of patients with unresectable locally advanced or metastatic triple-negative breast cancer.

Hyo S.  Han

Consulting or Advisory Role - Pfizer

Research Funding - Abbvie (Inst); Bristol-Myers Squibb (Inst); G1 Therapeutics (Inst); Novartis (Inst); Pfizer (Inst); Prescient Therapeutics (Inst); Seagen (Inst); TapImmune Inc. (Inst); Tesaro (Inst)

Carlos A.  Alemany

Speakers' Bureau - Alexion Pharmaceuticals

Research Funding - Eisai (Inst); Janssen (Inst); Novartis (Inst); Pfizer (Inst); Seagen (Inst)

Ursa Abigail  Brown-Glaberman

Consulting or Advisory Role - Novartis; Syndax

Research Funding - Seagen (Inst)

Timothy J.  Pluard

Consulting or Advisory Role - Genentech; Macrogenics; Pfizer

Speakers' Bureau - Genentech/Roche; Novartis; Pfizer; Tempus

Research Funding - Seagen (Inst)

Rajni  Sinha

Research Funding - Seagen (Inst)

Danielle  Sterrenberg

Consulting or Advisory Role - AstraZeneca

Speakers' Bureau - Puma Biotechnology; Tesaro

Research Funding - Seagen (Inst)

Travel, Accommodations, Expenses - Novartis; Tesaro

Kathy S.  Albain

Consulting or Advisory Role - Agendia; Genentech/Roche; Genentech/Roche; Genomic Health; Myriad Genetics; Novartis; Pfizer

Research Funding - Seagen; Seagen (Inst)

Other Relationship - Puma Biotechnology

Reva K.  Basho

Employment - Alignment Healthcare (I); Castlewood Treatment Center (I); DaVita (I)

Consulting or Advisory Role - HERON (Inst); Puma Biotechnology (Inst)

Research Funding - Seagen (Inst)

David  Biggs

Employment - AstraZeneca (I)

Stock and Other Ownership Interests  - AstraZeneca (I)

Research Funding - Seagen (Inst)

Travel, Accommodations, Expenses - AstraZeneca (I)

Valentina  Boni

Honoraria - Loxo

Consulting or Advisory Role - Guidepoint Global; OncoArt

Speakers' Bureau - Solti

Research Funding - Bayer (Inst); Bristol-Myers Squibb (Inst); CytomX Therapeutics (Inst); Incyte (Inst); Janssen Oncology (Inst); Kura Oncology (Inst); Lilly (Inst); Loxo (Inst); Menarini (Inst); Merck (Inst); Merus (Inst); Novartis (Inst); Pfizer (Inst); Puma Biotechnology (Inst); Roche/Genentech (Inst); Sanofi (Inst); Seagen (Inst); Synthon (Inst); Tesaro (Inst)

Travel, Accommodations, Expenses - START

Sami  Diab

Stock and Other Ownership Interests  - Conatus; Immunogen; Immunomedics; Novocure; Viking Medical

Honoraria - Agendia; AstraZeneca; Genomic Health; Lilly; Myriad Genetics; Novartis; Pfizer

Consulting or Advisory Role - Agendia; Genentech; Genomic Health; Lilly; Myriad Genetics; Novartis; Pfizer; Puma Biotechnology

Speakers' Bureau - Agendia; Genentech; Genomic Health; Lilly; Novartis; Pfizer; Puma Biotechnology

Research Funding - Pfizer (Inst); Seagen (Inst)

Travel, Accommodations, Expenses - Genentech; Lilly; Novartis; Pfizer

Michaela L.  Tsai

Research Funding - Seagen (Inst)

Katherine Hanna  Tkaczuk

Research Funding - Abbott/AbbVie (Inst); Angiochem (Inst); Biomarin (Inst); Cascadian Therapeutics (Inst); Genentech/Roche (Inst); Genentech/Roche (Inst); Novartis (Inst); Puma Biotechnology (Inst); Seagen (Inst); TapImmune Inc. (Inst)

Yinghui  Wang

Employment - Seagen

Stock and Other Ownership Interests  - Seagen

Travel, Accommodations, Expenses - Seagen

Zejing  Wang

Employment - Seagen

Stock and Other Ownership Interests  - Seagen

Travel, Accommodations, Expenses - Seagen

Jane Lowe  Meisel

Honoraria - Total Health Conferencing

Consulting or Advisory Role - Pfizer; Puma Biotechnology

Research Funding - Lilly; Pfizer; Seagen

Travel, Accommodations, Expenses - Pfizer; Puma Biotechnology; Total Health Conferencing