The following represents disclosure information provided by authors of this abstract. The program committee has reviewed all presenting author disclosure reports, identified potential conflicts of interest, and implemented strategies to manage those areas of conflict, where appropriate. All relationships are considered compensated. Relationships are self-held unless otherwise noted. I = Immediate Family Member, Inst = My Institution
 
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A phase I study of the APE1 protein inhibitor APX3330 in patients with advanced solid tumors.
 
Safi Shahda
Consulting or Advisory Role - AstraZeneca; Bayer; Eisai; Exelixis; Ipsen
Research Funding - Apexian Pharmaceuticals (Inst); Incyte (Inst); Merck (Inst)
 
Nehal J. Lakhani
Research Funding - Alexion Pharmaceuticals (Inst); Alexo Therapeutics (Inst); Apexian Pharmaceuticals (Inst); Asana Biosciences (Inst); Ascentage Pharma (Inst); BeiGene (Inst); Cerulean Pharma (Inst); Constellation Pharmaceuticals (Inst); Coordination Therapeutics (Inst); CytomX Therapeutics (Inst); Formation Biologics (Inst); Forty Seven (Inst); Incyte (Inst); InhibRx (Inst); Jounce Therapeutics (Inst); Livzon (Inst); Loxo (Inst); Macrogenics (Inst); Merck (Inst); Northern Biologics (Inst); Pfizer (Inst); Regeneron (Inst); Symphogen (Inst); TaiRx, Inc. (Inst); Tesaro (Inst)
 
Bert O'Neil
Consulting or Advisory Role - Amgen; Bayer; Bristol-Myers Squibb; Genentech/Roche; Merck
Speakers' Bureau - Celgene
Travel, Accommodations, Expenses - Bayer; Merck KGaA
 
Drew W. Rasco
Consulting or Advisory Role - Boehringer Ingelheim; Lilly
Research Funding - Abbvie (Inst); Aeglea Biotherapeutics (Inst); Apexian Pharmaceuticals (Inst); Asana Biosciences (Inst); Ascentage Pharma (Inst); Astex Pharmaceuticals (Inst); Birdie (Inst); Celgene (Inst); Compugen (Inst); Constellation Pharmaceuticals (Inst); Coordination Therapeutics (Inst); Eisai (Inst); Five Prime Therapeutics (Inst); GlaxoSmithKline (Inst); Incyte (Inst); Macrogenics (Inst); Merck (Inst); Millennium (Inst); Pharmacyclics (Inst); Rexahn Pharmaceuticals (Inst); Syndax (Inst)
Travel, Accommodations, Expenses - Asana Biosciences
 
Jun Wan
No Relationships to Disclose
 
Amber L Mosley
No Relationships to Disclose
 
Hao Liu
No Relationships to Disclose
 
Mark R. Kelley
Leadership - Apexian Pharmaceuticals
Stock and Other Ownership Interests - Apexian Pharmaceuticals
Consulting or Advisory Role - Apexian Pharmaceuticals
Patents, Royalties, Other Intellectual Property - I have a number of antibodies that have been licensed from Indiana University School of Medicine that are sold by various companies. The royalties come back to the school and I share in some of them.
 
Richard Adam Messmann
Employment - Endocyte
Leadership - Endocyte
Stock and Other Ownership Interests - Apexian Pharmaceuticals; Endocyte
Patents, Royalties, Other Intellectual Property - I old patents with both Endocyte Inc., and Apexian Pharmaceuticals, Inc. In both cases, all rights and royalties have been transferred to the respective companies.
Travel, Accommodations, Expenses - Apexian Pharmaceuticals; Endocyte