The following represents disclosure information provided by authors of this abstract. The program committee has reviewed all presenting author disclosure reports, identified potential conflicts of interest, and implemented strategies to manage those areas of conflict, where appropriate. All relationships are considered compensated. Relationships are self-held unless otherwise noted. I = Immediate Family Member, Inst = My Institution
 
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Patient-reported outcomes from two global multicenter clinical trials of children and adults with tropomyosin receptor kinase (TRK) fusion cancer receiving larotrectinib.
 
Shivaani Kummar
Stock and Other Ownership Interests - Drishti
Consulting or Advisory Role - Corvus Pharmaceuticals; Genentech; MedTree (I); Nodus Therapeutics; Seagen; ShangPharma Innovation
Research Funding - ADC Therapeutics (Inst); Advenchen Laboratories (Inst); Bristol-Myers Squibb (Inst); Corvus Pharmaceuticals (Inst); Dynavax Technologies (Inst); Incyte (Inst); Jounce Therapeutics (Inst); Loxo (Inst); Pfizer (Inst); Plexxikon (Inst); Taiho Pharmaceutical (Inst)
Travel, Accommodations, Expenses - Bayer
 
Leo Mascarenhas
Honoraria - Bayer
Consulting or Advisory Role - Bayer; Lilly (Inst)
Speakers' Bureau - Bayer
Research Funding - AstraZeneca/MedImmune (Inst)
Travel, Accommodations, Expenses - AstraZeneca/MedImmune; Bayer; Lilly
 
Birgit Geoerger
No Relationships to Disclose
 
Brian Turpin
No Relationships to Disclose
 
Michael Craig Cox
Employment - Amgen; Bayer; Loxo; Merck KGaA
Stock and Other Ownership Interests - Amgen; Bayer; Loxo; Merck KGaA
Patents, Royalties, Other Intellectual Property - US patent 62/318,041 issued to Loxo Oncology. (Inst)
 
Sandie Yu
Employment - Loxo; Medivation; Pfizer
Stock and Other Ownership Interests - Loxo; Medivation
Consulting or Advisory Role - Quorum Consulting
 
Shivani Nanda
Employment - Bayer
 
Florian Hiemeyer
Employment - Bayer
 
Karen N Keating
Employment - Bayer
 
Costel Chirila
Employment - RTI Health Solutions
 
Ari Gnanasakthy
Stock and Other Ownership Interests - Novartis
 
Eric Davenport
Employment - RTI Health Solutions
 
David S. Hong
Stock and Other Ownership Interests - MolecularMatch; Oncorena; Presagia
Honoraria - Adaptimmune; Baxter; Bayer; Merrimack
Consulting or Advisory Role - Adaptimmune; Alphasights; Axiom Biotechnologies; Baxter; Bayer; Eisai; Genentech; Gerson Lehrman Group; GroupH; Guidepoint Global; Janssen; Medscape; Merrimack; Numab; Pfizer; Seagen; Takeda; Trieza Therapeutics
Research Funding - Abbvie; Adaptimmune; Amgen; Amgen; AstraZeneca; Bayer; Bristol-Myers Squibb; Daiichi Sankyo; Eisai; Fate Therapeutics; Genentech; Genmab; Ignyta; Infinity Pharmaceuticals; Kite, a Gilead company; Kyowa Hakko Kirin; Lilly; Loxo; MedImmune; Merck; Mirati Therapeutics; miRNA Therapeutics; Molecular Templates; MOLOGEN; National Cancer Institute; Novartis; Pfizer; Seagen; Takeda
Travel, Accommodations, Expenses - Genmab; Loxo; miRNA Therapeutics
 
Alexander E. Drilon
Honoraria - Foundation Medicine; Medscape; MORE Health; OncLive; Peerview; PeerVoice; Physicans' Education Resource; Research to Practice; Targeted Oncology
Consulting or Advisory Role - AstraZeneca; Bayer; BeiGene; BerGenBio; Blueprint Medicines; Exelixis; Genentech/Roche; Helsinn Therapeutics; Hengrui Therapeutics; Ignyta; Loxo; MORE Health; Pfizer; Takeda/Millennium; TP Therapeutics; Tyra Biosciences; Verastem
Patents, Royalties, Other Intellectual Property - Wolters Kluwer (Royalties for Pocket Oncology)
Other Relationship - GlaxoSmithKline; Merck; Taiho Pharmaceutical; Teva