The following represents disclosure information provided by authors of this abstract. The program committee has reviewed all presenting author disclosure reports, identified potential conflicts of interest, and implemented strategies to manage those areas of conflict, where appropriate. All relationships are considered compensated. Relationships are self-held unless otherwise noted. I = Immediate Family Member, Inst = My Institution
 
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Time-to-treatment discontinuation (TTD) and real-world progression-free survival (rwPFS) as endpoints for comparative efficacy analysis between entrectinib trial and crizotinib real-world ROS1 fusion-positive (ROS1+) NSCLC patients.

Robert Charles  Doebele

Stock and Other Ownership Interests  - Rain Therapeutics

Consulting or Advisory Role - AstraZeneca; Bayer; GreenPeptide; Ignyta; OncoMed; Rain Therapeutics; Roche/Genentech; Takeda

Research Funding - Ignyta (Inst)

Patents, Royalties, Other Intellectual Property - Licensing fees for biologic materials from Genentech (Inst); Licensing fees for patent from Rain Therapeutics; Licensing Fees from Abbott Molecular for Patent PCT/US2013/057495; Licensing fees from Ignyta for biologic materials (Inst)

Travel, Accommodations, Expenses - Ignyta; Rain Therapeutics; Roche/Genentech

Laura  Perez

Employment - Roche

Stock and Other Ownership Interests  - Roche

Travel, Accommodations, Expenses - Roche

Huong  Trinh

Employment - Genentech

Stock and Other Ownership Interests  - Genentech

Travel, Accommodations, Expenses - Genentech (I)

Michael  Martinec

Employment - Roche

Stock and Other Ownership Interests  - Roche

Research Funding - Roche

Travel, Accommodations, Expenses - Roche

Reynaldo  Martina

Consulting or Advisory Role - Dompé Farmaceutici; Roche

Todd  Riehl

Employment - Genentech

Stock and Other Ownership Interests  - Genentech

Matthew  Krebs

Honoraria - Roche

Consulting or Advisory Role - Achilles Therapeutics; Janssen; Octimet; Roche

Research Funding - Roche (Inst)

Travel, Accommodations, Expenses - AstraZeneca; BerGenBio

Neal J.  Meropol

Employment - Flatiron Health

Stock and Other Ownership Interests  - Flatiron Health

Patents, Royalties, Other Intellectual Property - US Patent (20020031515): Methods of therapy for cancers characterized by over expression of the HER2 receptor protein

William Bruce  Wong

Employment - Genentech/Roche

Stock and Other Ownership Interests  - Allergan; Roche

Research Funding - Genentech/Roche

Gracy  Crane

Employment - Roche/Genentech

Stock and Other Ownership Interests  - Roche/Genentech

Travel, Accommodations, Expenses - Roche/Genentech