The following represents disclosure information provided by authors of this abstract. The program committee has reviewed all presenting author disclosure reports, identified potential conflicts of interest, and implemented strategies to manage those areas of conflict, where appropriate. All relationships are considered compensated. Relationships are self-held unless otherwise noted. I = Immediate Family Member, Inst = My Institution
 
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First-in-human first-in-class phase I trial of murlentamab, an anti-Mullerian-hormone receptor II (AMHRII) monoclonal antibody acting through tumor-associated macrophage (TAM) engagement, as single agent and in combination with carboplatin (C) and paclitaxel (P) in AMHRII-expressing advanced/metastatic gynecological cancer patients (pts).
 
Alexandra Leary
Honoraria - AstraZeneca; Clovis Oncology; Pharmamar; Tesaro
Consulting or Advisory Role - AstraZeneca; Biocad; Clovis Oncology; GamaMabs Pharma; Gritstone Bio; pfizer; Seagen; Tesaro
Research Funding - AstraZeneca (Inst); Clovis Oncology (Inst); Genentech (Inst); inivata (Inst); Merus (Inst); MSD Oncology (Inst)
Travel, Accommodations, Expenses - AstraZeneca
 
Ahmad Awada
Consulting or Advisory Role - Amgen; Bristol-Myers Squibb; Eisai; Ipsen; Leo Pharma; Lilly; MSD; Novartis; Pfizer; Roche
Travel, Accommodations, Expenses - Ipsen; Pfizer; Roche
 
Jean-Pierre Delord
Consulting or Advisory Role - Bristol-Myers Squibb; MSD Oncology; Novartis; Roche/Genentech
Research Funding - Bristol-Myers Squibb (Inst); Genentech (Inst); MSD Oncology (Inst)
 
Anne Floquet
Consulting or Advisory Role - AstraZeneca; Clovis Oncology; Roche; Tesaro
Travel, Accommodations, Expenses - AstraZeneca; PharmaMar; Roche; Tesaro
 
Isabelle Laure Ray-Coquard
Honoraria - AstraZeneca; Clovis Oncology; MSD Oncology; PharmaMar; Roche; Tesaro
Consulting or Advisory Role - Abbvie; Amgen; Genmab; Pfizer
Travel, Accommodations, Expenses - Roche
 
Cyril Abdeddaim
No Relationships to Disclose
 
Michel Fabbro
Honoraria - AstraZeneca
Travel, Accommodations, Expenses - Roche
 
Elsa Kalbacher
Consulting or Advisory Role - Roche
Travel, Accommodations, Expenses - Roche
 
Ignace Vergote
Consulting or Advisory Role - Advaxis (Inst); AstraZeneca (Inst); Clovis Oncology (Inst); Eisai (Inst); Genmab (Inst); Immunogen (Inst); Millennium (Inst); MSD Belgium (Inst); Oncoinvent (Inst); PharmaMar (Inst); Roche (Inst); Roche (Inst); Sotio (Inst); Tesaro (Inst)
Research Funding - Amgen (Inst); Genmab (Inst); Oncoinvent (Inst); Roche (Inst); Stichting tegen kanker (Inst)
Travel, Accommodations, Expenses - AstraZeneca; Genmab; PharmaMar; Roche; Takeda; Tesaro
 
Susana N. Banerjee
Honoraria - Roche
Consulting or Advisory Role - AstraZeneca (Inst); AstraZeneca/MedImmune; Clovis Oncology; Clovis Oncology (Inst); GamaMabs Pharma; Merck; Roche (Inst); Seagen; Tesaro; Tesaro (Inst)
Research Funding - AstraZeneca (Inst); Janssen-Cilag (Inst)
Travel, Accommodations, Expenses - AstraZeneca; Clovis Oncology; Tesaro
 
François-Xavier Frenois
No Relationships to Disclose
 
Grégory Noël
No Relationships to Disclose
 
Olivier Lantz
No Relationships to Disclose
 
Lydie Cassard
No Relationships to Disclose
 
Agnès Coste
No Relationships to Disclose
 
Marine Villard
No Relationships to Disclose
 
Fanny Lemee
Employment - GamaMabs Pharma
Patents, Royalties, Other Intellectual Property - Genomic Vision
 
Isabelle Marie Tabah-Fisch
Employment - GamaMabs Pharma
Stock and Other Ownership Interests - GamaMabs Pharma
 
Christophe Le Tourneau
Honoraria - Bristol-Myers Squibb; Merck Serono; MSD; Nanobiotix; Novartis; Roche
Consulting or Advisory Role - Amgen; AstraZeneca; Bristol-Myers Squibb; GlaxoSmithKline; Merck Serono; MSD; Nanobiotix; Roche
Travel, Accommodations, Expenses - AstraZeneca; Bristol-Myers Squibb; MSD