The following represents disclosure information provided by authors of this abstract. The program committee has reviewed all presenting author disclosure reports, identified potential conflicts of interest, and implemented strategies to manage those areas of conflict, where appropriate. All relationships are considered compensated. Relationships are self-held unless otherwise noted. I = Immediate Family Member, Inst = My Institution
 
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A phase I multicenter study to assess the safety, tolerability, and immunogenicity of mRNA-4157 alone in patients with resected solid tumors and in combination with pembrolizumab in patients with unresectable solid tumors.
 
Howard A. Burris
Employment - HCA Healthcare
Leadership - HCA Healthcare
Stock and Other Ownership Interests - HCA Healthcare
Consulting or Advisory Role - AstraZeneca (Inst); Bristol-Myers Squibb (Inst); FORMA Therapeutics (Inst); Janssen (Inst); MedImmune (Inst); Mersana (Inst); Novartis (Inst); Roche/Genentech (Inst); TG Therapeutics (Inst)
Research Funding - Abbvie (Inst); Agios (Inst); AstraZeneca (Inst); Bayer (Inst); BioAtla (Inst); BioMed Valley Discoveries (Inst); Boehringer Ingelheim (Inst); Bristol-Myers Squibb (Inst); Celgene (Inst); Celldex (Inst); CicloMed (Inst); CytomX Therapeutics (Inst); Daiichi Sankyo (Inst); eFFECTOR Therapeutics (Inst); Gilead Sciences (Inst); GlaxoSmithKline (Inst); H3 Biomedicine (Inst); Harpoon therapeutics (Inst); Immunocore (Inst); Incyte (Inst); Janssen (Inst); Jiangsu Hengrui Medicine (Inst); Jounce Therapeutics (Inst); Lilly (Inst); Loxo (Inst); Macrogenics (Inst); MedImmune (Inst); Merck (Inst); Mersana (Inst); Millennium (Inst); Moderna Therapeutics (Inst); Neon Therapeutics (Inst); Novartis (Inst); OncoMed (Inst); Pfizer (Inst); PTC Therapeutics (Inst); Regeneron (Inst); Revolution Medicines (Inst); Roche/Genentech (Inst); Sanofi (Inst); Seagen (Inst); Takeda (Inst); Tarveda Therapeutics (Inst); Tesaro (Inst); TG Therapeutics (Inst); Valent Technologies (Inst); Verastem (Inst); Vertex (Inst)
Expert Testimony - Novartis
 
Manish R. Patel
Consulting or Advisory Role - Pfizer/EMD Serono; Pharmacyclics/Janssen
Speakers' Bureau - Celgene; Exelixis; Genentech/Roche; Taiho Pharmaceutical
 
Daniel C. Cho
Consulting or Advisory Role - Bristol-Myers Squibb; Exelis; Genentech; HUYA Bioscience International; Nektar; Pfizer; Prometheus; PureTech
 
Jeffrey Melson Clarke
Consulting or Advisory Role - AstraZeneca; Guardant Health
Speakers' Bureau - Guardant Health; Lilly; Merck
Research Funding - Abbvie; Adaptimmune; Bristol-Myers Squibb; Genentech/Roche; medpacto; Moderna Therapeutics; Spectrum Pharmaceuticals
 
Martin Gutierrez
Stock and Other Ownership Interests - COTA
Consulting or Advisory Role - Bayer; Karyopharm Therapeutics; Lilly
Speakers' Bureau - Bristol-Myers Squibb; Foundation One Inc; Lilly; Merck
Research Funding - Abbvie (Inst); Acceleron Pharma (Inst); Bayer (Inst); Bayer (Inst); Bristol-Myers Squibb (Inst); Celgene (Inst); Daiichi Sankyo (Inst); Eisai (Inst); EMD Serono (Inst); Esanex (Inst); Genentech/Roche (Inst); Gilead Sciences (Inst); Incyte (Inst); Karyopharm Therapeutics (Inst); Lilly (Inst); Loxo (Inst); MedImmune (Inst); Merck (Inst); Mirati Therapeutics (Inst); Moderna Therapeutics (Inst); Novartis (Inst); Regeneron (Inst); Rexahn Pharmaceuticals (Inst); Sanofi (Inst); Seagen (Inst); Tesaro (Inst); TG Therapeutics (Inst)
 
Tal Z. Zaks
Employment - Moderna Therapeutics
Leadership - Adaptimmune; Moderna Therapeutics
Stock and Other Ownership Interests - Moderna Therapeutics
 
Joshua Frederick
Employment - Moderna Therapeutics
Stock and Other Ownership Interests - Moderna Therapeutics
 
Kristen Hopson
Employment - Moderna Therapeutics
Stock and Other Ownership Interests - Moderna Therapeutics
 
Kinjal Mody
Employment - Moderna Therapeutics
Stock and Other Ownership Interests - Moderna Therapeutics
 
Alverina Binanti-Berube
Employment - Moderna Therapeutics
Stock and Other Ownership Interests - Moderna Therapeutics
 
Celine Robert-Tissot
Employment - Moderna Therapeutics
Stock and Other Ownership Interests - Moderna Therapeutics
 
Bree Goldstein
Employment - Moderna Therapeutics
Stock and Other Ownership Interests - Moderna Therapeutics
 
Ben Breton
Employment - Moderna Therapeutics
Stock and Other Ownership Interests - Moderna Therapeutics
 
Jing Sun
Employment - Moderna Therapeutics
Stock and Other Ownership Interests - Moderna Therapeutics
 
Shan Zhong
Employment - Moderna Therapeutics
Stock and Other Ownership Interests - Moderna Therapeutics
 
Scott K. Pruitt
Employment - Merck Sharp & Dohme
Stock and Other Ownership Interests - Merck Sharp & Dohme
 
Karen Keating
Employment - Moderna Therapeutics
Stock and Other Ownership Interests - Moderna Therapeutics
 
Robert S. Meehan
Employment - Moderna Therapeutics
Stock and Other Ownership Interests - Moderna Therapeutics
 
Justin F. Gainor
Honoraria - ARIAD; Incyte; Merck; Novartis; Pfizer; Takeda
Consulting or Advisory Role - Agios; Amgen; Array BioPharma; Bristol-Myers Squibb; Genentech; Jounce Therapeutics; Loxo; Merck; Oncorus; Regeneron; Takeda; Theravance
Research Funding - Adaptimmune (Inst); Alexo Therapeutics (Inst); ARIAD; Array BioPharma (Inst); AstraZeneca (Inst); Blueprint Medicines (Inst); Bristol-Myers Squibb (Inst); Genentech; Jounce Therapeutics (Inst); Merck (Inst); Moderna Therapeutics (Inst); Novartis (Inst); Tesaro (Inst)