The following represents disclosure information provided by authors of this abstract. The program committee has reviewed all presenting author disclosure reports, identified potential conflicts of interest, and implemented strategies to manage those areas of conflict, where appropriate. All relationships are considered compensated. Relationships are self-held unless otherwise noted. I = Immediate Family Member, Inst = My Institution
 
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CONTESSA: A multinational, multicenter, randomized, phase III registration study of tesetaxel plus a reduced dose of capecitabine in patients (pts) with HER2-, hormone receptor + (HR+) locally advanced or metastatic breast cancer (LA/MBC) who have previously received a taxane.
 
Joyce O'Shaughnessy
Honoraria - Abbvie; Agendia; Amgen; AstraZeneca; Bristol-Myers Squibb; Celgene; Eisai; Genentech; Genomic Health; GRAIL; HERON; Immunomedics; Ipsen; Jounce Therapeutics; Lilly; Merck; Myriad Pharmaceuticals; Novartis; Odonate Therapeutics; Pfizer; Puma Biotechnology; Roche; Seagen; Syndax
Consulting or Advisory Role - Abbvie; Agendia; Amgen; AstraZeneca; Bristol-Myers Squibb; Celgene; Eisai; Genentech; Genomic Health; GRAIL; HERON; Immunomedics; Ipsen; Jounce Therapeutics; Lilly; Merck; Myriad Pharmaceuticals; Novartis; Odonate Therapeutics; Pfizer; Puma Biotechnology; Roche; Seagen; Syndax
Speakers' Bureau - AstraZeneca; Lilly; Novartis
Research Funding - Seagen (Inst)
Travel, Accommodations, Expenses - Abbvie; Agendia; Amgen; Celgene; Eisai; Eisai; Genomic Health; GRAIL; Ipsen; Jounce Therapeutics; Lilly; Myriad Pharmaceuticals; Novartis; Pfizer; Puma Biotechnology; Seagen
 
Martine Piccart
Honoraria - AstraZeneca; Camel-IDS; Crescendo Biologics; Debiopharm Group; G1 Therapeutics; HUYA Bioscience International; Immunomedics; Lilly; Menarini; MSD; Novartis; Odonate Therapeutics; Oncolytics; Periphagen; Pfizer; PharmaMar; Radius Health; Radius Health; Roche/Genentech; Seagen
Consulting or Advisory Role - AstraZeneca; Camel-IDS; Crescendo Biologics; Debiopharm Group; G1 Therapeutics; HUYA Bioscience International; Immunomedics; Lilly; Menarini; MSD; Novartis; Odonate Therapeutics; Oncolytics; Periphagen; Pfizer; PharmaMar; Roche/Genentech; Seagen
Research Funding - AstraZeneca (Inst); Lilly (Inst); MSD (Inst); Novartis (Inst); Pfizer (Inst); Radius Health (Inst); Roche/Genentech (Inst); SERVIER (Inst); Synthon (Inst)
 
Lee S. Schwartzberg
Stock and Other Ownership Interests - Vector Oncology
Honoraria - Amgen; E.R. Squibb Sons, LLC; Genentech; Helsinn Healthcare; NanoString Technologies; Napo Pharmaceuticals; Novartis; Pfizer; Pfizer; Taiho Pharmaceutical
Consulting or Advisory Role - Amgen; AstraZeneca; Bristol-Myers Squibb; Caris Life Sciences; E.R. Squibb Sons, LLC; Genentech; Genomic Health; Helsinn Therapeutics; Lilly; Novartis; Pfizer; Roche; Spectrum Pharmaceuticals; Tesaro; Vector Oncology
Research Funding - Amgen (Inst); Bayer Health (Inst); E.R. Squibb Sons, LLC (Inst); E.R. Squibb Sons, LLC (Inst); Genentech (Inst); GlaxoSmithKline (Inst); MedImmune (Inst); Medivation (Inst); Novartis (Inst); Pfizer (Inst); Sanofi (Inst); Spectrum Pharmaceuticals (Inst); Tesaro (Inst)
 
Javier Cortes
Stock and Other Ownership Interests - MedSIR
Honoraria - Celgene; Eisai; Novartis; Pfizer; Roche; Samsung
Consulting or Advisory Role - AstraZeneca; Biothera; Celgene; Cellestia Biotech; Daiichi Sankyo; ERYTECH Pharma; Merus; Polyphor; Roche; Seagen
Research Funding - ARIAD (Inst); AstraZeneca (Inst); Baxalta (Inst); Bayer (Inst); Eisai (Inst); Guardant Health (Inst); Merck Sharp & Dohme (Inst); Pfizer (Inst); Pique (Inst); Puma Biotechnology (Inst); Queen Mary university of London (Inst); Roche (Inst)
Travel, Accommodations, Expenses - Eisai; Novartis; Pfizer; Roche
 
Nadia Harbeck
Honoraria - Amgen; Celgene; Genomic Health; NanoString Technologies; Novartis; Pfizer; Roche
Consulting or Advisory Role - Agendia; AstraZeneca; Celgene; Daiichi Sankyo; Lilly; Merck Sharp & Dohme; Novartis; Odonate Therapeutics; Pfizer; Roche/Genentech; Sandoz; Seagen
Research Funding - Lilly (Inst); MSD (Inst); Novartis (Inst); Pfizer (Inst); Roche/Genentech (Inst)
 
Seock-Ah Im
Consulting or Advisory Role - AstraZeneca; Eisai; Novartis; Pfizer; Roche/Genentech
Research Funding - AstraZeneca; Pfizer
Travel, Accommodations, Expenses - MSD Oncology; Novartis; Roche/Genentech
Other Relationship - Roche
 
Hope S. Rugo
Research Funding - Daiichi Sankyo (Inst); Eisai (Inst); Genentech (Inst); Immunomedics (Inst); Lilly (Inst); Macrogenics (Inst); Merck (Inst); Novartis (Inst); OBI Pharma (Inst); Odonate Therapeutics (Inst); Pfizer (Inst); Seagen (Inst)
Travel, Accommodations, Expenses - Amgen; Mylan; Novartis; OBI Pharma; Pfizer; Puma Biotechnology; Roche/Genentech; Sanofi
 
Michael Untch
Honoraria - Amgen; AstraZeneca; Celgene; Daiichi Sankyo; Eisai Germany; Lilly; Merck Sharp & Dome; Mundipharma; Myriad Genetics; Pfizer; Roche Pharma AG; Teva
Consulting or Advisory Role - Abbvie (Inst); Amgen (Inst); Daiichi Sankyo (Inst); Eisai (Inst); Lilly (Inst); Merck Sharp & Dome (Inst); Mundipharma (Inst); Pfizer (Inst); Roche Pharma AG (Inst)
 
Denise A. Yardley
Consulting or Advisory Role - Biotheranostics (Inst); Bristol-Myers Squibb (Inst); Celgene (Inst); Daiichi Sankyo/Lilly (Inst); Eisai (Inst); Genentech/Roche (Inst); NanoString Technologies (Inst); Novartis (Inst)
Speakers' Bureau - Genentech/Roche; Genentech/Roche; Novartis
Research Funding - Abbvie (Inst); AstraZeneca (Inst); Clovis Oncology (Inst); Daiichi Sankyo (Inst); Eisai (Inst); Genentech/Roche (Inst); Immunomedics (Inst); InventisBio (Inst); Lilly (Inst); Macrogenics (Inst); MedImmune (Inst); Medivation (Inst); Merck (Inst); Novartis (Inst); Oncothyreon (Inst); Pfizer (Inst); Syndax (Inst); Tesaro (Inst)
Travel, Accommodations, Expenses - Genentech/Roche; Novartis
 
Igor Bondarenko
No Relationships to Disclose
 
Stephen Chan
Employment - GenesisCare
Consulting or Advisory Role - Daiichi Sankyo; Inc Research; Novartis; OpenHealth Communications; Pfizer; PharmaMar
Travel, Accommodations, Expenses - GenesisCare
 
Veronique Dieras
Honoraria - Astellas Medivation; Eisai; Lilly; Nektar; Novartis; Pfizer; Roche
Consulting or Advisory Role - Astellas Medivation; Eisai; Lilly; Nektar; Novartis; Pfizer; Roche/Genentech
Speakers' Bureau - Eisai; Lilly; Novartis; Pfizer; Roche
Travel, Accommodations, Expenses - AstraZeneca; Lilly; Pfizer; Roche
 
Mark D. Pegram
Employment - Loxo (I)
Honoraria - See consulting below
Consulting or Advisory Role - Daiichi Sankyo; Genentech/Roche; Macrogenics; Seagen
 
Stew Kroll
Employment - Odonate Therapeutics
Stock and Other Ownership Interests - Odonate Therapeutics
 
Joseph P. O'Connell
Employment - inVentiv Health; Odonate Therapeutics
Leadership - Odonate Therapeutics
Stock and Other Ownership Interests - inVentiv Health; Odonate Therapeutics
Travel, Accommodations, Expenses - inVentiv Health; Odonate Therapeutics
 
Jeff Vacirca
Employment - New York Cancer and Blood Specialists
Leadership - Odonate Therapeutics
Stock and Other Ownership Interests - Flatiron Health; Odonate Therapeutics
Consulting or Advisory Role - AmerisourceBergen
 
Thomas Wei
Employment - Odonate Therapeutics
Stock and Other Ownership Interests - Acorda Therapeutics; Allergan; Cardiome; HERON; MabVax; Mallinckrodt; Merck; NicOx; Pfizer
Travel, Accommodations, Expenses - Odonate Therapeutics
 
Kevin Tang
Employment - Odonate Therapeutics
Leadership - HERON; La Jolla Pharma; Odonate Therapeutics; Sentier Therapeutics
Stock and Other Ownership Interests - BioCryst; Biomarin; BioReference Laboratories; Celldex; Cyclacel; HERON; Horizon Pharma; Ignyta; Infinity Pharmaceuticals; La Jolla Pharma; Lipocine; Merrimack; Mirati Therapeutics; Nektar; OncoGenex; OPKO Health; RxAnte; Salix; Sarepta Therapeutics; Sentier Therapeutics
Travel, Accommodations, Expenses - Odonate Therapeutics; Sentier Therapeutics
 
Andrew David Seidman
Honoraria - Celgene; Eisai; Genentech/Roche; Genomic Health; Lilly; Novartis/Pfizer
Consulting or Advisory Role - Celgene; Eisai; Genentech/Roche; Lilly; Nektar; Novartis; Odonate Therapeutics
Speakers' Bureau - AstraZeneca/MedImmune; Celgene; Eisai; Genentech/Roche; Genomic Health; Lilly; Novartis/Pfizer
Research Funding - Bayer; Nektar (Inst); Odonate Therapeutics (Inst)
Travel, Accommodations, Expenses - Celgene; Eisai; Genentech/Roche; Genomic Health