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Phase 1 study evaluating the safety, tolerability, pharmacokinetics (PK), and efficacy of AMG 510, a novel small molecule KRASG12C inhibitor, in advanced solid tumors. |
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Consulting or Advisory Role - Amgen; Array BioPharma; Genentech/Roche |
Speakers' Bureau - Amgen; Taiho Pharmaceutical |
Research Funding - Amgen (Inst); AstraZeneca (Inst); Novartis (Inst) |
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Consulting or Advisory Role - Amgen; Bayer; Bristol-Myers Squibb; Genentech/Roche; Merck |
Speakers' Bureau - Celgene |
Travel, Accommodations, Expenses - Bayer; Merck KGaA |
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Consulting or Advisory Role - Amgen; Merck Serono (Inst); Roche (Inst) |
Travel, Accommodations, Expenses - Amgen |
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Employment - HealthONE; Sarah Cannon Research Institute |
Consulting or Advisory Role - EMD Serono; Fujifilm (Inst) |
Research Funding - 3-V Biosciences (Inst); Abbvie (Inst); ADC Therapeutics (Inst); Aileron Therapeutics (Inst); ARMO BioSciences (Inst); AstraZeneca (Inst); BeiGene (Inst); Biothera (Inst); Celgene (Inst); Celldex (Inst); Celldex (Inst); Celldex (Inst); Celldex (Inst); Celldex (Inst); Ciclomed (Inst); Curegenix (Inst); Curis (Inst); DelMar Pharmaceuticals (Inst); eFFECTOR Therapeutics (Inst); EMD Serono (Inst); Fujifilm (Inst); Genmab (Inst); Hutchison MediPharma (Inst); Ignyta (Inst); Incyte (Inst); Jacobio (Inst); Jounce Therapeutics (Inst); Kolltan Pharmaceuticals (Inst); Lilly; Loxo (Inst); MedImmune (Inst); Merck (Inst); Millennium (Inst); miRNA Therapeutics (Inst); Novartis (Inst); OncoMed (Inst); Precision Oncology (Inst); Regeneron (Inst); Rgenix (Inst); Strategia Therapeutics (Inst); Syndax (Inst); Taiho Pharmaceutical (Inst); Takeda (Inst); Tarveda Therapeutics (Inst); Tarveda Therapeutics (Inst); Tesaro (Inst); Tocagen (Inst); Vegenics (Inst) |
Patents, Royalties, Other Intellectual Property - Handbook of Targeted Cancer Therapy |
Travel, Accommodations, Expenses - Bristol-Myers Squibb; EMD Serono; Fujifilm; Millennium; Sarah Cannon Research Institute |
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Consulting or Advisory Role - Amgen; BeiGene; Bionomics; Eisai; Lilly; Novartis |
Research Funding - Bionomics (Inst); GlaxoSmithKline (Inst); Novartis (Inst); Roche (Inst) |
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Travel, Accommodations, Expenses - Bristol-Myers Squibb; MSD; Zucero Therapeutics |
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Honoraria - Abbvie; Genentech; Janssen; Millennium; Roche |
Consulting or Advisory Role - Abbvie; Adaptimmune; AstraZeneca; Bristol-Myers Squibb; Celgene; EMD Serono; Genentech; GlaxoSmithKline; Inivata; Lilly; Merck; Nektar; Pfizer; Phillips Gilmore Oncology; Roche |
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Stock and Other Ownership Interests - Amgen |
Travel, Accommodations, Expenses - Amgen |
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Stock and Other Ownership Interests - Amgen |
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Stock and Other Ownership Interests - Amgen |
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No Relationships to Disclose |
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Stock and Other Ownership Interests - MolecularMatch; Oncorena; Presagia |
Honoraria - Adaptimmune; Baxter; Bayer; Merrimack |
Consulting or Advisory Role - Adaptimmune; Alphasights; Axiom Biotechnologies; Baxter; Bayer; Eisai; Genentech; Gerson Lehrman Group; GroupH; Guidepoint Global; Janssen; Medscape; Merrimack; Numab; Pfizer; Seagen; Takeda; Trieza Therapeutics |
Research Funding - Abbvie; Adaptimmune; Amgen; Amgen; AstraZeneca; Bayer; Bristol-Myers Squibb; Daiichi Sankyo; Eisai; Fate Therapeutics; Genentech; Genmab; Ignyta; Infinity Pharmaceuticals; Kite, a Gilead company; Kyowa Hakko Kirin; Lilly; Loxo; MedImmune; Merck; Mirati Therapeutics; miRNA Therapeutics; Molecular Templates; MOLOGEN; National Cancer Institute; Novartis; Pfizer; Seagen; Takeda |
Travel, Accommodations, Expenses - Genmab; Loxo; miRNA Therapeutics |