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A phase I study of H3B-6527 in hepatocellular carcinoma (HCC) or intrahepatic cholangiocarcinoma (ICC) patients (pts). |
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No Relationships to Disclose |
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Consulting or Advisory Role - Merck |
Research Funding - Abbvie (Inst); ACEA Biosciences (Inst); Adaptimmune (Inst); Amgen (Inst); AstraZeneca (Inst); Bayer (Inst); BeiGene (Inst); Boehringer Ingelheim (Inst); Bristol-Myers Squibb (Inst); Celgene (Inst); E-therapeutics (Inst); Eisai (Inst); GlaxoSmithKline (Inst); Janssen (Inst); Menarini (Inst); Merck (Inst); Nanobiotix (Inst); Novartis (Inst); Pfizer (Inst); PharmaMar (Inst); PsiOxus Therapeutics (Inst); Puma Biotechnology (Inst); Regeneron (Inst); RigonTEC (Inst); Roche (Inst); Sanofi (Inst); Sierra Oncology (Inst); Synthon (Inst); Taiho Pharmaceutical (Inst); Takeda (Inst); Tesaro (Inst); Transgene (Inst) |
Expert Testimony - Medscape/Bayer; Nanobiotix |
Travel, Accommodations, Expenses - Sanofi/Regeneron |
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Consulting or Advisory Role - Bayer; Eisai; Gilead Sciences |
Research Funding - Bayer; BMS Brazil; H3 Biomedicine |
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Speakers' Bureau - Boehringer Ingelheim; Merck |
Patents, Royalties, Other Intellectual Property - National Institutes of Health patent |
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Honoraria - Baxter; Bristol-Myers Squibb; Celgene; Fresenius Kabi; Ipsen; LEO Pharma; Merck; Novartis; nutricia; pfizer; Sanofi; Shire; Taiho Pharmaceutical |
Consulting or Advisory Role - Celgene; Immuneering; LEO Pharma; Nutricia; Pfizer; Yinuoke |
Research Funding - Bayer (Inst); Bristol-Myers Squibb (Inst); Corvus Pharmaceuticals (Inst); Pfizer (Inst); Rexahn Pharmaceuticals (Inst) |
Patents, Royalties, Other Intellectual Property - My lab discovered that all the competitive tyrosine kinase inhibitors such as sunitinib and gefitinib have additional pharmacological properties. This additional pharmacologic property causes intestinal epithelial cells to active their chloride channels l |
Travel, Accommodations, Expenses - Amgen; Ipsen; LEO Pharma; Novartis Canada Pharmaceuticals Inc; Nutricia; pfizer |
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Honoraria - ASLAN Pharmaceuticals; BMS Brazil; MSD |
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Travel, Accommodations, Expenses - Pfizer |
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Stock and Other Ownership Interests - COTA |
Consulting or Advisory Role - Bayer; Karyopharm Therapeutics; Lilly |
Speakers' Bureau - Bristol-Myers Squibb; Foundation One Inc; Lilly; Merck |
Research Funding - Abbvie (Inst); Acceleron Pharma (Inst); Bayer (Inst); Bayer (Inst); Bristol-Myers Squibb (Inst); Celgene (Inst); Daiichi Sankyo (Inst); Eisai (Inst); EMD Serono (Inst); Esanex (Inst); Genentech/Roche (Inst); Gilead Sciences (Inst); Incyte (Inst); Karyopharm Therapeutics (Inst); Lilly (Inst); Loxo (Inst); MedImmune (Inst); Merck (Inst); Mirati Therapeutics (Inst); Moderna Therapeutics (Inst); Novartis (Inst); Regeneron (Inst); Rexahn Pharmaceuticals (Inst); Sanofi (Inst); Seagen (Inst); Tesaro (Inst); TG Therapeutics (Inst) |
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Research Funding - Celgene; H3 Biomedicine; Syndax; Taiho Pharmaceutical |
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Consulting or Advisory Role - Adaptimmune; AstraZeneca; Bayer; Bristol-Myers Squibb; BTG; H3 Biomedicine; Ipsen; Lilly; Merck; Onxeo; Sirtex Medical |
Speakers' Bureau - Bayer; Bristol-Myers Squibb; Sirtex Medical |
Research Funding - Bristol-Myers Squibb (Inst); Sirtex Medical (Inst) |
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Consulting or Advisory Role - Abbvie; Gilead Sciences |
Speakers' Bureau - Abbvie; Gilead Sciences; MSD |
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Employment - H3 Biomedicine |
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Employment - H3 Biomedicine |
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Employment - H3 Biomedicine |
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Employment - H3 Biomedicine |
Travel, Accommodations, Expenses - H3 Biomedicine |
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Employment - H3 Biomedicine |
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Employment - H3 Biomedicine |
Leadership - H3 Biomedicine |
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Employment - H3 Biomedicine |
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Consulting or Advisory Role - AstraZeneca; Bayer; Bristol-Myers Squibb; Eisai; Exelixis; Genentech/Roche; Lilly; Merck; Novartis; Pfizer |
Research Funding - Bayer (Inst); Bristol-Myers Squibb (Inst); Eisai (Inst); Lilly (Inst); Merck (Inst); Novartis (Inst); Pfizer (Inst); Roche/Genentech (Inst) |
Expert Testimony - Novartis |