The following represents disclosure information provided by authors of this abstract. The program committee has reviewed all presenting author disclosure reports, identified potential conflicts of interest, and implemented strategies to manage those areas of conflict, where appropriate. All relationships are considered compensated. Relationships are self-held unless otherwise noted. I = Immediate Family Member, Inst = My Institution
 
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A phase 1, open-label, multicenter study to assess the safety, tolerability, and immunogenicity of mRNA-4157 alone in subjects with resected solid tumors and in combination with pembrolizumab in subjects with unresectable solid tumors (Keynote-603).
 
Howard A. Burris III
Employment - HCA Healthcare
Leadership - HCA Healthcare
Stock and Other Ownership Interests - HCA Healthcare
Consulting or Advisory Role - AstraZeneca (Inst); Boehringer Ingelheim (Inst); Bristol-Myers Squibb (Inst); Celgene (Inst); Celgene (Inst); Eisai (Inst); FORMA Therapeutics (Inst); Incyte (Inst); Janssen (Inst); MedImmune (Inst); Mersana (Inst); Novartis (Inst); Roche/Genentech (Inst); Tolero Pharmaceuticals (Inst)
Research Funding - Agios (Inst); Archer (Inst); Arvinas (Inst); AstraZeneca (Inst); BioAtla (Inst); BioMed Valley Discoveries (Inst); Boehringer Ingelheim (Inst); Bristol-Myers Squibb (Inst); Celgene (Inst); CicloMed (Inst); CytomX Therapeutics (Inst); eFFECTOR Therapeutics (Inst); Gilead Sciences (Inst); GlaxoSmithKline (Inst); Harpoon therapeutics (Inst); Immunocore (Inst); Incyte (Inst); Janssen (Inst); Jiangsu Hengrui Medicine (Inst); Jounce Therapeutics (Inst); Kyocera (Inst); Lilly (Inst); Loxo (Inst); Macrogenics (Inst); MedImmune (Inst); Merck (Inst); Millennium (Inst); Moderna Therapeutics (Inst); Novartis (Inst); Revolution Medicines (Inst); Roche/Genentech (Inst); Seagen (Inst); Takeda (Inst); Tesaro (Inst); TG Therapeutics (Inst); Verastem (Inst); Vertex (Inst)
Expert Testimony - Novartis
 
Manish R. Patel
Consulting or Advisory Role - Pfizer/EMD Serono; Pharmacyclics/Janssen
Speakers' Bureau - Celgene; Exelixis; Genentech/Roche; Taiho Pharmaceutical
 
Daniel C. Cho
Consulting or Advisory Role - HUYA Bioscience International; Nektar; PureTech; Torque
Expert Testimony - Abbott/AbbVie; Genentech
 
Jeffrey Melson Clarke
Consulting or Advisory Role - AstraZeneca; Guardant Health
Speakers' Bureau - Guardant Health; Lilly; Merck
Research Funding - Abbvie; Adaptimmune; Bristol-Myers Squibb; Genentech/Roche; medpacto; Moderna Therapeutics; Spectrum Pharmaceuticals
 
Martin Gutierrez
Stock and Other Ownership Interests - COTA
Consulting or Advisory Role - Bayer; Karyopharm Therapeutics; Lilly
Speakers' Bureau - Bristol-Myers Squibb; Foundation One Inc; Lilly; Merck
Research Funding - Abbvie (Inst); Acceleron Pharma (Inst); Bayer (Inst); Bayer (Inst); Bristol-Myers Squibb (Inst); Celgene (Inst); Daiichi Sankyo (Inst); Eisai (Inst); EMD Serono (Inst); Esanex (Inst); Genentech/Roche (Inst); Gilead Sciences (Inst); Incyte (Inst); Karyopharm Therapeutics (Inst); Lilly (Inst); Loxo (Inst); MedImmune (Inst); Merck (Inst); Mirati Therapeutics (Inst); Moderna Therapeutics (Inst); Novartis (Inst); Regeneron (Inst); Rexahn Pharmaceuticals (Inst); Sanofi (Inst); Seagen (Inst); Tesaro (Inst); TG Therapeutics (Inst)
 
Tal Z. Zaks
Employment - Moderna Therapeutics
Leadership - Adaptimmune
Stock and Other Ownership Interests - Moderna Therapeutics
 
Joshua Frederick
Employment - Moderna Therapeutics
Stock and Other Ownership Interests - Moderna Therapeutics
Patents, Royalties, Other Intellectual Property - Moderna Therapeutics
 
Kristen Hopson
Employment - Moderna Therapeutics
Stock and Other Ownership Interests - Moderna Therapeutics
Patents, Royalties, Other Intellectual Property - Moderna Therapeutics
 
Kinjal Mody
Employment - Moderna Therapeutics
Stock and Other Ownership Interests - Moderna Therapeutics
 
Alverina Binanti-Berube
Employment - Moderna Therapeutics
Stock and Other Ownership Interests - Moderna Therapeutics
 
Celine Robert-Tissot
Employment - Moderna Therapeutics
Stock and Other Ownership Interests - Moderna Therapeutics
 
Kristen Cowens
Employment - Moderna Therapeutics
Stock and Other Ownership Interests - Moderna Therapeutics
 
Ben Breton
Employment - Moderna Therapeutics
Stock and Other Ownership Interests - Moderna Therapeutics
 
Shan Zhong
Employment - Moderna Therapeutics
Stock and Other Ownership Interests - Moderna Therapeutics
 
Honghong Zhou
Employment - Moderna Therapeutics
Stock and Other Ownership Interests - Moderna Therapeutics
 
Pamela Sarah Cohen
Employment - Blueprint Medicines; Moderna Therapeutics
Stock and Other Ownership Interests - Moderna Therapeutics
 
Karen Keating
Employment - Moderna Therapeutics
Stock and Other Ownership Interests - Moderna Therapeutics
 
Robert S. Meehan
Employment - Moderna Therapeutics
Stock and Other Ownership Interests - Moderna Therapeutics
 
Justin F. Gainor
Employment - Ironwood Pharmaceuticals (I)
Honoraria - ARIAD; Incyte; Merck; Novartis; Pfizer; Takeda
Consulting or Advisory Role - Agios; Amgen; Array BioPharma; Blueprint Medicines; Bristol-Myers Squibb; Genentech; Jounce Therapeutics; Loxo; Merck; Oncorus; Regeneron; Takeda; Theravance
Research Funding - Adaptimmune (Inst); Alexo Therapeutics (Inst); ARIAD; Array BioPharma (Inst); AstraZeneca (Inst); Blueprint Medicines (Inst); Bristol-Myers Squibb (Inst); Genentech; Jounce Therapeutics (Inst); Merck (Inst); Moderna Therapeutics (Inst); Novartis (Inst); Tesaro (Inst)