The following represents disclosure information provided by authors of this abstract. The program committee has reviewed all presenting author disclosure reports, identified potential conflicts of interest, and implemented strategies to manage those areas of conflict, where appropriate. All relationships are considered compensated. Relationships are self-held unless otherwise noted. I = Immediate Family Member, Inst = My Institution
 
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Association of an RNA signature (RS) with emergence of ICOS hi CD4 T cells and efficacy outcomes for the ICOS agonist vopratelimab (vopra) and nivolumab (nivo) in patients (pts) on the ICONIC trial.
 
Timothy A Yap
Consulting or Advisory Role - Aduro Biotech; Almac Diagnostics; AstraZeneca; Atrin Pharmaceuticals; Bayer; Bristol-Myers Squibb; Calithera Biosciences; Clovis Oncology; Cybrexa Therapeutics; EMD Serono; Ignyta; Janssen; Merck; Pfizer; Roche; Seagen; Tesaro; Vertex
Research Funding - AstraZeneca; Bayer; Constellation Pharmaceuticals; Jounce Therapeutics; Kyowa Hakko Kirin; Lilly; Pfizer; Seagen; Tesaro; Vertex
Patents, Royalties, Other Intellectual Property - MD Anderson Cancer Center holds the intellectual property rights to IACS-010759 and its designated use. (Inst)
Travel, Accommodations, Expenses - Atrin Pharmaceuticals; Calithera Biosciences; EMD Serono; Leidos Biomedical Research; Lilly; Pfizer; Tesaro
 
Justin F. Gainor
Employment - Ironwood Pharmaceuticals (I)
Honoraria - ARIAD; Incyte; Merck; Novartis; Pfizer; Takeda
Consulting or Advisory Role - Agios; Amgen; Array BioPharma; Blueprint Medicines; Bristol-Myers Squibb; Genentech; Jounce Therapeutics; Loxo; Merck; Oncorus; Regeneron; Takeda; Theravance
Research Funding - Adaptimmune (Inst); Alexo Therapeutics (Inst); ARIAD; Array BioPharma (Inst); AstraZeneca (Inst); Blueprint Medicines (Inst); Bristol-Myers Squibb (Inst); Genentech; Jounce Therapeutics (Inst); Merck (Inst); Moderna Therapeutics (Inst); Novartis (Inst); Tesaro (Inst)
 
Howard A. Burris
No Relationships to Disclose
 
Shivaani Kummar
Stock and Other Ownership Interests - Drishti
Consulting or Advisory Role - Bayer; Boehringer Ingelheim; Corvus Pharmaceuticals; Genentech; Harbour BioMed; MedTree (I); Mundipharma; Nodus Therapeutics; Seagen; ShangPharma Innovation
Research Funding - ADC Therapeutics (Inst); Advenchen Laboratories (Inst); Astex Pharmaceuticals (Inst); Bayer (Inst); Bristol-Myers Squibb (Inst); Corvus Pharmaceuticals (Inst); Dynavax Technologies (Inst); Incyte (Inst); Jounce Therapeutics (Inst); Loxo (Inst); Pfizer (Inst); Plexxikon (Inst); Taiho Pharmaceutical (Inst)
Travel, Accommodations, Expenses - Bayer
 
Russell Kent Pachynski
Consulting or Advisory Role - Bayer; Bristol-Myers Squibb; Dendreon; EMD Serono; Genomic Health; Jounce Therapeutics; Pfizer/EMD Serono; Sanofi
Speakers' Bureau - AstraZeneca; Dendreon; Genentech/Roche; Genomic Health; Merck; Sanofi
Research Funding - Janssen Oncology
Travel, Accommodations, Expenses - Genentech/Roche
 
Margaret K. Callahan
Employment - Bristol-Myers Squibb (I); Bristol-Myers Squibb (I); Celgene (I); Kleo Pharmaceuticals (I)
Consulting or Advisory Role - AstraZeneca; Merck; Moderna Therapeutics
Research Funding - Bristol-Myers Squibb (Inst)
Other Relationship - Clinical Care Options; Potomac Center for Medical Education
 
Patricia LoRusso
Honoraria - Five Prime Therapeutics
Consulting or Advisory Role - Agenus; Agios; Agios; Cybrexa Therapeutics; CytomX Therapeutics; Five Prime Therapeutics; Genentech; Halozyme; Roche/Genentech; Sotio
Research Funding - Genentech (Inst)
Travel, Accommodations, Expenses - Genentech
 
Scott S. Tykodi
Consulting or Advisory Role - Bristol-Myers Squibb
Research Funding - Bristol-Myers Squibb (Inst); Calithera Biosciences (Inst); Genentech (Inst); GlaxoSmithKline (Inst); Jounce Therapeutics (Inst); Merck Sharp & Dohme (Inst); Nektar (Inst); Pfizer (Inst)
Patents, Royalties, Other Intellectual Property - Patent pending (Inst)
 
Geoffrey Thomas Gibney
Consulting or Advisory Role - Array BioPharma; Bristol-Myers Squibb; Genentech/Roche; Incyte; Jounce Therapeutics; Newlink Genetics; Newlink Genetics; Novartis
Speakers' Bureau - Genentech/Roche
 
Gerald Steven Falchook
Employment - HealthONE; Sarah Cannon Research Institute
Consulting or Advisory Role - EMD Serono; Fujifilm (Inst)
Speakers' Bureau - Total Health Conferencing
Research Funding - 3-V Biosciences (Inst); Abbvie (Inst); ADC Therapeutics (Inst); Aileron Therapeutics (Inst); Amgen (Inst); ARMO BioSciences (Inst); AstraZeneca (Inst); BeiGene (Inst); Bioatla (Inst); Biothera (Inst); Celgene (Inst); Celldex (Inst); Ciclomed (Inst); Curegenix (Inst); Curis (Inst); DelMar Pharmaceuticals (Inst); eFFECTOR Therapeutics (Inst); EMD Serono (Inst); Exelixis (Inst); Fujifilm (Inst); Genmab (Inst); Hutchison MediPharma (Inst); Ignyta (Inst); Incyte (Inst); Jacobio (Inst); Jounce Therapeutics (Inst); Kolltan Pharmaceuticals (Inst); Lilly (Inst); Loxo (Inst); MedImmune (Inst); Merck (Inst); Millennium (Inst); miRNA Therapeutics (Inst); Novartis (Inst); OncoMed (Inst); Precision Oncology (Inst); Regeneron (Inst); Rgenix (Inst); Strategia Therapeutics (Inst); Syndax (Inst); Taiho Pharmaceutical (Inst); Takeda (Inst); Tarveda Therapeutics (Inst); Tesaro (Inst); Tocagen (Inst); Vegenics (Inst)
Patents, Royalties, Other Intellectual Property - Handbook of Targeted Cancer Therapy
Travel, Accommodations, Expenses - Bristol-Myers Squibb; EMD Serono; Fujifilm; Millennium; Sarah Cannon Research Institute
 
Osama E. Rahma
Employment - Outcomes4me
Leadership - Outcomes4me
Honoraria - Alaunus Global; Clinical Care Options; Leerink; Merck; MI Bioresearch; PRMA Consulting
Consulting or Advisory Role - Alcimed; Celgene; Defined Health; Five Prime Therapeutics; Genentech; Gfk; GlaxoSmithKline; Imvax; Leerink; Leerink; Maverick Therapeutics; Merck; PureTech; Putnam Associates
Research Funding - Amgen (Inst); Merck
Patents, Royalties, Other Intellectual Property - PD-1/PD-L1 (Inst); Pending patent (DFCI 2386.010) (Inst)
Travel, Accommodations, Expenses - Clinical Care Options; Genentech; Merck; PRMA Consulting; PureTech
 
Tanguy Y. Seiwert
Honoraria - AstraZeneca; Bristol-Myers Squibb; Merck
Consulting or Advisory Role - Aduro Biotech; AstraZeneca; Bayer; Bristol-Myers Squibb; Celgene; Innate Pharma; Merck; Nanobiotix; Roche Molecular Diagnostics
Research Funding - Bristol-Myers Squibb (Inst); Jounce Therapeutics (Inst); Merck (Inst)
Travel, Accommodations, Expenses - AstraZeneca; Bayer; Bristol-Myers Squibb; Celgene; Innate Pharma; Merck; Nanobiotix; Roche Molecular Diagnostics
 
Kyriakos P. Papadopoulos
Consulting or Advisory Role - ArQule; Bayer
Research Funding - 3D Medicines (Inst); Abbvie (Inst); ADC Therapeutics (Inst); Amgen (Inst); ARMO BioSciences (Inst); ArQule (Inst); Bayer (Inst); Calithera Biosciences (Inst); Curegenix (Inst); Daiichi Sankyo (Inst); EMD Serono (Inst); Formation Biologics (Inst); Incyte (Inst); Jounce Therapeutics (Inst); MabSpace Biosciences (Inst); MedImmune (Inst); Merck (Inst); Mersana (Inst); OncoMed (Inst); Peloton Therapeutics (Inst); Regeneron (Inst); Sanofi (Inst); Syros Pharmaceuticals (Inst)
 
James Walter Mier
No Relationships to Disclose
 
Yasmin Hashambhoy-Ramsay
Employment - Jounce Therapeutics
Stock and Other Ownership Interests - Jounce Therapeutics
Travel, Accommodations, Expenses - Jounce Therapeutics
 
Daniel Felitsky
Employment - Jounce Therapeutics
Stock and Other Ownership Interests - Jounce Therapeutics
Travel, Accommodations, Expenses - Jounce Therapeutics
 
David Y. Lee
Employment - Jounce Therapeutics
Stock and Other Ownership Interests - Jounce Therapeutics
Travel, Accommodations, Expenses - Jounce Therapeutics
 
Lara McGrath
Employment - Jounce Therapeutics
Stock and Other Ownership Interests - Jounce Therapeutics
Travel, Accommodations, Expenses - Jounce Therapeutics
 
Christopher Harvey
Employment - Jounce Therapeutics
Stock and Other Ownership Interests - Jounce Therapeutics
Travel, Accommodations, Expenses - Jounce Therapeutics
 
Ellen Hooper
Employment - Jounce Therapeutics
Stock and Other Ownership Interests - Jounce Therapeutics
Travel, Accommodations, Expenses - Jounce Therapeutics