The following represents disclosure information provided by authors of this abstract. The program committee has reviewed all presenting author disclosure reports, identified potential conflicts of interest, and implemented strategies to manage those areas of conflict, where appropriate. All relationships are considered compensated. Relationships are self-held unless otherwise noted. I = Immediate Family Member, Inst = My Institution
 
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INDIGO: A global, randomized, double-blind, phase III study of vorasidenib (VOR; AG-881) vs placebo in patients (pts) with residual or recurrent grade II glioma with an isocitrate dehydrogenase 1/2 (IDH1/2) mutation.
 
Ingo K. Mellinghoff
Honoraria - Roche
Consulting or Advisory Role - Agios; Black Diamond Therapeutics; Debiopharm Group; Puma Biotechnology; Voyager Therapeutics
Research Funding - Amgen; General Electric; Lilly
Travel, Accommodations, Expenses - Agios; AstraZeneca; Puma Biotechnology; Roche; Voyager Therapeutics
 
Martin J. Van Den Bent
Consulting or Advisory Role - Abbvie; Agios; Bayer; Boehringer Ingelheim; Bristol-Myers Squibb; carthera; Celgene; Daiichi Sankyo; Genenta Science; Nerviano Medical Sciences
Research Funding - Abbvie (Inst)
 
Jennifer Leigh Clarke
Consulting or Advisory Role - Agios
Research Funding - Agios (Inst); Merck (Inst); Novartis (Inst)
 
Elizabeth Anne Maher
Consulting or Advisory Role - Agios; Curadev; Curadev (I); Forma Therapeutics
Research Funding - Curadev; Curadev (I)
Travel, Accommodations, Expenses - Agios; FORMA Therapeutics
 
Katherine B. Peters
Consulting or Advisory Role - Abbvie; Agios; Bayer; Boehringer Ingelheim; Eisai
Research Funding - Abbvie; Agios; BioMimetix; BioMimetix; Bristol-Myers Squibb; Novocure
 
Mehdi Touat
Consulting or Advisory Role - Agios; Integragen; Taiho Pharmaceutical
Travel, Accommodations, Expenses - Merck Sharp & Dohme
 
John Frederick De Groot
Employment - ZIOPHARM Oncology (I)
Leadership - ZIOPHARM Oncology (I)
Stock and Other Ownership Interests - Gilead Sciences; ZIOPHARM Oncology (I)
Consulting or Advisory Role - Abbvie; Agios; AstraZeneca; Blue Earth Diagnostics; Boston Biomedical; CarThera; Deciphera; Five Prime Therapeutics; Foundation Medicine; Genentech/Roche; GenomiCare; GW Pharmaceuticals; Insys Therapeutics; Kadmon; Kairos Ventures; KIYATEC; Merck; Mundipharma Research; Novogen; Vascular Biogenics
Research Funding - Deciphera; EMD Serono; Lilly; Mundipharma; Novartis; Sanofi
Patents, Royalties, Other Intellectual Property - AstraZeneca - Research Support; Deciphera Pharmaceuticals - Research Support; Eli Lilly - Research Support; EMD-Serono - Research Support; Novartis - Research Support; Sanofi-Aventis - Research Support
Travel, Accommodations, Expenses - Blue Earth Diagnostics
 
Macarena Ines De La Fuente
Consulting or Advisory Role - Agios; FORMA Therapeutics; Foundation Medicine; Puma Biotechnology
Other Relationship - OncLIve (I); Oncology Information Group (I); Targeted Oncology (I)
 
Isabel Arrillaga-Romany
Honoraria - Merck
Consulting or Advisory Role - Agios; Boehringer Ingelheim; FORMA Therapeutics; Insys Therapeutics; Karus Therapeutics
Research Funding - Astex Pharmaceuticals
 
Wolfgang Wick
Consulting or Advisory Role - Abbvie; MSD Oncology (Inst); Roche/Genentech (Inst); Roche/Genentech (Inst)
Research Funding - Apogenix (Inst); Pfizer (Inst); Roche (Inst)
 
Benjamin M. Ellingson
Consulting or Advisory Role - Agios; Bristol-Myers Squibb; Imaging Endpoints; Medicenna; MedQIA; Nativis; Northwest Biotherapeutics; Novogen; Omniox; Roche/Genentech; Siemens; Tocagen
Research Funding - Agios; Roche/Genentech; Siemens
Travel, Accommodations, Expenses - Siemens
 
Steven Schoenfeld
Employment - Agios
Stock and Other Ownership Interests - Agios
 
Feng Tai
Employment - Agios
Stock and Other Ownership Interests - Agios
 
Kha Le
Employment - Agios
Stock and Other Ownership Interests - Agios
 
Min Lu
Employment - Agios
Stock and Other Ownership Interests - Agios
 
Lori Steelman
Employment - Agios; Infinity Pharmaceuticals
Stock and Other Ownership Interests - Infinity Pharmaceuticals
 
Islam Hassan
Employment - Agios
Stock and Other Ownership Interests - Agios
 
Shuchi Sumant Pandya
Employment - Agios
Stock and Other Ownership Interests - Agios
Research Funding - Agios
Travel, Accommodations, Expenses - Agios
 
Patrick Y. Wen
Consulting or Advisory Role - Agios; AstraZeneca; Bayer; Blue Earth Diagnostics; Deciphera; deciphera; ElevateBio; Immunomic Therapeutics; Imvax; Integral Health; Karyopharm Therapeutics; KIYATEC; Puma Biotechnology; QED Therapeutics; Taiho Pharmaceutical; Taiho Pharmaceutical; Tocagen; Vascular Biogenics; VBI Vaccines; Voyager Therapeutics
Speakers' Bureau - Merck; Prime Oncology
Research Funding - Abbvie (Inst); Agios (Inst); AstraZeneca (Inst); AstraZeneca (Inst); Bayer (Inst); Beigene (Inst); Celgene (Inst); Kazia Therapeutics (Inst); Lilly (Inst); MediciNova (Inst); Merck (Inst); Novartis (Inst); Oncoceutics (Inst); Puma Biotechnology (Inst); Vascular Biogenics (Inst); VBI Vaccines (Inst)
 
Timothy Francis Cloughesy
Stock and Other Ownership Interests - Katmai Pharmaceuticals; Notable Labs
Consulting or Advisory Role - Abbvie; Agios; Alexion Pharmaceuticals; Amgen; Bayer; Boehringer Ingelheim; Boston Biomedical; Bristol-Myers Squibb; Celgene; cortice; Deciphera; DelMar Pharmaceuticals; Genocea Biosciences; GW Pharmaceuticals; Human Longevity, Inc; Insys Therapeutics; Karyopharm Therapeutics; KIYATEC; Lilly; Merck; NewGen Therapeutics; Notable Labs; Novartis; Novocure; Novogen; Oxigene; Pascal Biosciences; Pfizer; Puma Biotechnology; QED Therapeutics; Roche/Genentech; Sunovion; Tocagen; VBI Vaccines; VBL Therapeutics; wellcome trust
Patents, Royalties, Other Intellectual Property - U.S. Provisional Application No.: 62/819,322 Title: COMPOSITIONS AND METHODS FOR TREATING CANCER Filing Date: March 15, 2019 Inventor(s): David A. Nathanson et al. FH Reference No.: UCH-17760 (32246-17760) Your Reference No.: [UCLA 2019-630-1] US
Other Relationship - Global Coalition for Adaptive Research