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Phase I study of AMG 757, a half-life extended bispecific T-cell engager (HLE BiTE immune therapy) targeting DLL3, in patients with small cell lung cancer (SCLC). |
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Stock and Other Ownership Interests - CAMBIUM MEDICAL TECHNOLOGIES |
Consulting or Advisory Role - Abbvie; Amgen; ARMO BioSciences; AstraZeneca; Bayer; BerGenBio; Boehringer Ingelheim; Bristol-Myers Squibb; Celgene; Eisai; EMD Serono; G1 Therapeutics; HERON; Lilly; Lilly; MedImmune; Merck; Novartis; PharmaMar; Sandoz; Seagen; Takeda; Xcovery |
Speakers' Bureau - Abbvie |
Research Funding - Abbvie (Inst); Aeglea Biotherapeutics (Inst); Amgen (Inst); Astellas Pharma (Inst); AstraZeneca/MedImmune (Inst); Bayer (Inst); Bristol-Myers Squibb (Inst); Celgene (Inst); Corvus Pharmaceuticals; Fujifilm (Inst); G1 Therapeutics (Inst); Incyte (Inst); Loxo/Lilly (Inst); Merck (Inst); Novartis (Inst); Pfizer (Inst); Regeneron (Inst); Stem CentRx (Inst); United Therapeutics (Inst) |
Patents, Royalties, Other Intellectual Property - DR4 Modulation and its Implications in EGFR-Target Cancer Therapy Ref:18089 PROV (CSP) United States Patent Application No. 62/670,210 June 26, 2018 (Co-Inventor) (Inst); OVERCOMING ACQUIRED RESISTANCE TO CHEMOTHERAPY TREATMENTS THROUGH SUPPRESSION OF STAT3 (Inst); SELECTIVE CHEMOTHERAPY TREATMENTS AND DIAGNOSTIC METHODS RELATED THERETO (Inst); Soluble FAS ligand as a biomarker of recurrence in thyroid cancer; provisional patent 61/727,519 (Inventor) (Inst) |
Other Relationship - EMD Serono; Roche/Genentech |
(OPTIONAL) Uncompensated Relationships - Reflexion Medical |
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Honoraria - Axiom Biotechnologies; Bristol-Myers Squibb; Celgene; Pfizer |
Consulting or Advisory Role - Abbvie; Amgen; AstraZeneca; BioNTech; Boehringer Ingelheim; Bristol-Myers Squibb; Cantargia AB; Celgene; EMD Serono; Genentech; Genmab; HUYA Bioscience International; Lilly; Merck; Novartis; Pfizer; PharmaMar; Regeneron; Rgenix; Sonnet; Takeda; Trovagene |
Research Funding - Bristol-Myers Squibb (Inst); Celgene (Inst); Lilly (Inst); Merck (Inst); Millennium (Inst) |
Travel, Accommodations, Expenses - Amgen; Bristol-Myers Squibb; Celgene; Clovis Oncology; Genentech; Lilly; Merck; Novartis |
Other Relationship - Incyte; Takeda; University of Pennsylvania |
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No Relationships to Disclose |
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Leadership - Altum Sequencing; European Medicines Agency (I); Genomica |
Honoraria - Advanced Accelerator Applications; Amgen; AstraZeneca; Bayer; Blueprint Medicines; Boehringer Ingelheim; Bristol-Myers Squibb; Celgene; Incyte; Ipsen; Lilly; Merck Serono; MSD; Novartis; Pfizer; PharmaMar; Roche/Genentech; Sanofi; Servier; Sysmex |
Research Funding - AstraZeneca; Bristol-Myers Squibb |
Travel, Accommodations, Expenses - AstraZeneca; Bristol-Myers Squibb; MSD; Pfizer; Roche; Takeda |
Other Relationship - Amgen (I); Ipsen (I); Merck (I); Novartis (I); Pfizer (I); Roche; Roche (I); Sanofi (I); SERVIER (I) |
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Honoraria - Abbvie; Genentech/Abbvie; Geneplus |
Consulting or Advisory Role - Abbvie; Achilles Therapeutics; Amgen; AstraZeneca/MedImmune; Bristol-Myers Squibb; Celgene; EMD Serono; Genentech/Roche; GlaxoSmithKline; Ignyta; Janssen; Jounce Therapeutics; Lilly; Merck Serono; Nektar; Pfizer; Phillips Gilmore Oncology; Roche |
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Honoraria - AstraZeneca; Boehringer Ingelheim (Inst); Genentech/Roche (Inst); Merck Sharp & Dohme (Inst) |
Consulting or Advisory Role - AstraZeneca (Inst); Bristol-Myers Squibb (Inst); Janssen (Inst); Merck Sharp & Dohme (Inst) |
Research Funding - Amgen (Inst); Ascentage Pharma (Inst); AstraZeneca (Inst); BeiGene (Inst); Benitec Biopharma (Inst); Boehringer Ingelheim (Inst); Bristol-Myers Squibb (Inst); Genentech/Roche (Inst); Janssen (Inst); Lilly (Inst); Merck Sharp & Dohme (Inst); Novartis (Inst); Pfizer (Inst) |
Travel, Accommodations, Expenses - Genentech/Roche; Merck Sharp & Dohme |
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Consulting or Advisory Role - Abbvie (Inst); Achilles Therapeutics (Inst); Association of Community Cancer Centers (ACCC) (Inst); Astellas Pharma (I); AstraZeneca (Inst); Atreca (Inst); Boehringer Ingelheim (Inst); Calithera Biosciences (Inst); Genentech/Roche (Inst); GlaxoSmithKline (Inst); Gritstone Bio (Inst); Guardant Health (Inst); Incyte (Inst); Janssen Oncology (Inst); Lilly (Inst); Loxo (Inst); Merck (Inst); Mirati Therapeutics (Inst); Novartis (Inst); Otsuka (I); Pfizer (Inst); Ribon Therapeutics (Inst); Sanofi (Inst) |
Research Funding - Abbvie (Inst); Acerta Pharma (Inst); Adaptimmune (Inst); Amgen (Inst); Apexigen (Inst); Arcus Biosciences (Inst); Array BioPharma (Inst); AstraZeneca (Inst); Atreca (Inst); BeiGene (Inst); Birdie (Inst); Boehringer Ingelheim (Inst); Checkpoint Therapeutics (Inst); Corvus Pharmaceuticals (Inst); CytomX Therapeutics (Inst); Daiichi Sankyo (Inst); Dynavax Technologies (Inst); EMD Serono (Inst); Genentech/Roche (Inst); Genmab (Inst); Genocea Biosciences (Inst); GlaxoSmithKline (Inst); Gritstone Bio (Inst); Guardant Health (Inst); Hengrui Pharmaceutical (Inst); Immunocore (Inst); Incyte (Inst); Janssen (Inst); Jounce Therapeutics (Inst); Kadmon (Inst); Lilly (Inst); Loxo (Inst); Lycera (Inst); Merck (Inst); Mirati Therapeutics (Inst); Neovia Oncology (Inst); Novartis (Inst); OncoMed (Inst); Pfizer (Inst); Regeneron (Inst); Ribon Therapeutics (Inst); Sanofi (Inst); Shattuck Labs (Inst); Stem CentRx (Inst); Syndax (Inst); Takeda (Inst); Tarveda Therapeutics (Inst); TCR2 Therapeutics (Inst); University of Michigan (Inst); WindMIL (Inst) |
Travel, Accommodations, Expenses - Abbvie; Astellas Pharma; AstraZeneca; Boehringer Ingelheim; Bristol-Myers Squibb; Clovis Oncology; Daiichi Sankyo; EMD Serono; Exelixis; Genentech; Incyte; Janssen Oncology; Lilly; Merck; Novartis; Pfizer; Sanofi; Sysmex; Vapotherm |
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Honoraria - Abbvie; Amco; AstraZeneca; Boehringer Ingelheim; Bristol-Myers Squibb; Chugai Pharma; Daiichi Sankyo; MSD; Ono Pharmaceutical; Taiho Pharmaceutical |
Consulting or Advisory Role - Abbvie; Boehringer Ingelheim |
Research Funding - Abbvie; Amgen; Daiichi Sankyo; MSD |
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Travel, Accommodations, Expenses - Amgen; Boehringer Ingelheim; Janssen-Cilag |
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Consulting or Advisory Role - Abbvie; ARIAD; Iovance Biotherapeutics; Novartis; Octimet |
Speakers' Bureau - AstraZeneca; Merck |
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Consulting or Advisory Role - Abbvie; AstraZeneca; Cell Medica; Ipsen; Medivation; MSD; Regeneron; Roche; Takeda |
Speakers' Bureau - Boehringer Ingelheim |
Research Funding - Amgen (Inst); AstraZeneca (Inst); Bristol-Myers Squibb (Inst); Novartis (Inst); Pfizer (Inst) |
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No Relationships to Disclose |
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Consulting or Advisory Role - G1 Therapeutics; PharmaMar |
Research Funding - Amgen (Inst); Daiichi Sankyo (Inst) |
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Consulting or Advisory Role - Abbvie; AstraZeneca; Bristol-Myers Squibb; Seagen; Takeda |
Research Funding - Abbvie (Inst); Amgen (Inst); Bayer (Inst); Incuron (Inst); Ipsen (Inst); Loxo (Inst); Regeneron (Inst); Seagen (Inst); Symphogen (Inst); Takeda (Inst); Tesaro (Inst) |
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Stock and Other Ownership Interests - Coordination Pharmaceuticals |
Honoraria - Abbvie; Amgen; Ascendis Pharma (I); AstraZeneca; Bristol-Myers Squibb; Celgene; EMD Serono; Genentech; GlaxoSmithKline; Lilly; Merck; Novartis; Radius Health (I); Regeneron; Takeda (I) |
Consulting or Advisory Role - Abbvie; Amgen; Ascendis Pharma (I); AstraZeneca; Bristol-Myers Squibb; Celgene; EMD Serono; Genentech; GlaxoSmithKline; Lilly; Merck; Novartis; Radius Health (I); Regeneron; Takeda (I) |
Research Funding - Abbvie; Bristol-Myers Squibb; Celgene; Novartis |
Travel, Accommodations, Expenses - Abbvie; Amgen; AstraZeneca; Bristol-Myers Squibb; Celgene; EMD Serono; Genentech; GlaxoSmithKline; Lilly; Merck; Novartis; Regeneron |
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Consulting or Advisory Role - Abbvie; Ascentage Pharma; Bristol-Myers Squibb; Genentech/Roche |
Research Funding - Abbvie (Inst); Amgen (Inst); Bristol-Myers Squibb (Inst); GlaxoSmithKline (Inst); Merrimack (Inst) |
Travel, Accommodations, Expenses - Abbvie/Stemcentrx; AstraZeneca; Bristol-Myers Squibb; Bristol-Myers Squibb |
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Consulting or Advisory Role - Abbvie; AstraZeneca; Boehringer Ingelheim; Bristol-Myers Squibb; Genentech; Genentech/Roche |
Research Funding - Abbvie; Amgen; AstraZeneca; Boehringer Ingelheim; Bristol-Myers Squibb; Lilly; Millennium; OncoMed; Onyx; Stem CentRx |
Travel, Accommodations, Expenses - Abbvie; AstraZeneca; Genentech/Roche |
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Stock and Other Ownership Interests - Amgen |
Travel, Accommodations, Expenses - Amgen |
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Stock and Other Ownership Interests - Amgen |