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CodeBreak 100: Phase I study of AMG 510, a novel KRASG12C inhibitor, in patients (pts) with advanced solid tumors other than non-small cell lung cancer (NSCLC) and colorectal cancer (CRC). |
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Stock and Other Ownership Interests - MolecularMatch; Oncorena; Presagia |
Consulting or Advisory Role - Alphasights; Axiom Biotechnologies; Bayer; Genentech; Gerson Lehrman Group; GroupH; Guidepoint Global; Infinity Pharmaceuticals; Medscape; Merrimack; Numab; Pfizer; PrimE Oncology; Seagen; Takeda; Trieza Therapeutics; WebMD |
Research Funding - Abbvie; Adaptimmune; Aldai Norte; Amgen; AstraZeneca/MedImmune; Bayer; Daiichi Sankyo; Fate Therapeutics; Genentech; Infinity Pharmaceuticals; Kite, a Gilead company; Kura Oncology; MedImmune; Mirati Therapeutics; Molecular Templates; National Cancer Institute; Pfizer; Seagen; Shattuck Labs; TCR2 Therapeutics; TP Therapeutics |
Travel, Accommodations, Expenses - AACR; ASCO; Bayer Schering Pharma; Genmab; Society for Immunotherapy of Cancer |
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Travel, Accommodations, Expenses - Bristol-Myers Squibb; MSD; Zucero Therapeutics |
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Honoraria - Amgen; AstraZeneca; Bayer; Bristol-Myers Squibb; Genentech/Roche; KisoJi Biotechnology; Merck; Pfizer; Tesaro |
Consulting or Advisory Role - Amgen; AstraZeneca/MedImmune; Bayer; Bristol-Myers Squibb; Genentech/Roche; KisoJi Biotechnology; Merck; Pfizer |
Research Funding - AstraZeneca; Genentech/Roche |
Travel, Accommodations, Expenses - AstraZeneca; Genentech/Roche; GlaxoSmithKline; Gritstone Bio; Pfizer |
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Honoraria - AstraZeneca; Bayer; Boehringer Ingelheim; Bristol-Myers Squibb; Genentech/Roche; Lilly; Merck Serono; MSD Oncology; Novartis; Pfizer; Pierre Fabre; Pierre Fabre; Takeda |
Consulting or Advisory Role - AstraZeneca/MedImmune; Bayer; Boehringer Ingelheim; Bristol-Myers Squibb; Lilly; Merck Serono; MSD Oncology; Novartis; Pfizer; Pierre Fabre; Roche/Genentech; Takeda |
Research Funding - Abbvie (Inst); Amgen (Inst); AstraZeneca/MedImmune (Inst); Bayer (Inst); Boehringer Ingelheim (Inst); Bristol-Myers Squibb (Inst); Eisai (Inst); Innate Pharma (Inst); Ipsen (Inst); Lilly (Inst); Merck Serono (Inst); MSD Oncology (Inst); Novartis (Inst); Pfizer (Inst); Pierre Fabre (Inst); Roche/Genentech (Inst); Sanofi/Aventis (Inst); Takeda (Inst) |
Travel, Accommodations, Expenses - AstraZeneca/MedImmune; Bristol-Myers Squibb; MSD Oncology; Roche/Genentech |
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Research Funding - Abbvie (Inst); Amgen (Inst); AstraZeneca (Inst); BeiGene (Inst); Blueprint Medicines (Inst); Boehringer Ingelheim (Inst); Bristol-Myers Squibb (Inst); Celgene (Inst); Cristal Therapeutics (Inst); Daiichi Sankyo (Inst); GlaxoSmithKline (Inst); Ignyta (Inst); Inivata (Inst); Ipsen (Inst); Janssen Oncology (Inst); Lilly (Inst); Merck KGaA (Inst); MSD Oncology (Inst); Nektar (Inst); Onxeo (Inst); OSE Immunotherapeutics (Inst); Pfizer (Inst); PharmaMar (Inst); Roche/Genentech (Inst); Sanofi (Inst); SERVIER (Inst); Spectrum Pharmaceuticals (Inst); Takeda (Inst); Tiziana Therapeutics (Inst); Tolero Pharmaceuticals (Inst) |
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Honoraria - Bayer; Lilly Japan; Ono Pharmaceutical; Sanofi; Taiho Pharmaceutical |
Consulting or Advisory Role - Boehringer Ingelheim; Takeda |
Research Funding - Amgen (Inst); AstraZeneca (Inst); Boehringer Ingelheim (Inst); Chugai Pharma (Inst); Daiichi Sankyo (Inst); GlaxoSmithKline (Inst); GlaxoSmithKline (Inst); Incyte (Inst); Ono Pharmaceutical (Inst); Taiho Pharmaceutical (Inst); Takeda (Inst) |
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Honoraria - AstraZeneca/MedImmune; GlaxoSmithKline |
Research Funding - AMGEN (Inst); AstraZeneca (Inst); Bristol-Myers Squibb (Inst); Tesaro (Inst) |
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Stock and Other Ownership Interests - Abbvie; Bristol-Myers Squibb; Johnson & Johnson |
Consulting or Advisory Role - Genentech; Sanofi/Regeneron |
Speakers' Bureau - Bristol-Myers Squibb; Sanofi/Regeneron |
Travel, Accommodations, Expenses - Sanofi/Regeneron |
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Research Funding - Abbvie (Inst); ACCRU (Inst); Amgen (Inst); Boehringer Ingelheim (Inst); Boston Biomedical (Inst); Ignyta (Inst); Isofol Medical (Inst); NSABP Foundation (Inst); NSABP FOUNDATION (Inst); OncoMed (Inst); Shire (Inst); XBiotech (Inst) |
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Consulting or Advisory Role - Abbvie/Stemcentrx; Blueprint Medicines; Novartis; Thermo Fisher Scientific |
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Stock and Other Ownership Interests - Amgen |
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No Relationships to Disclose |
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Stock and Other Ownership Interests - Amgen |
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Consulting or Advisory Role - Guardant Health; Hengrui Therapeutics |
Research Funding - Amgen (Inst); AstraZeneca (Inst); Daiichi Sankyo (Inst); GRAIL (Inst); Guardant Health (Inst); Hengrui Therapeutics (Inst); Lilly (Inst); MORE Health (Inst); Roche/Genentech (Inst) |
Patents, Royalties, Other Intellectual Property - US62/514,661 (Inst); US62/685,057 (Inst) |