The following represents disclosure information provided by authors of this abstract. The program committee has reviewed all presenting author disclosure reports, identified potential conflicts of interest, and implemented strategies to manage those areas of conflict, where appropriate. All relationships are considered compensated. Relationships are self-held unless otherwise noted. I = Immediate Family Member, Inst = My Institution
 
Open Payments is a public database containing information reported by companies about payments made to US-licensed physicians (Open Payments)
 
 
Consulting or Advisory Role - AstraZeneca; Novartis; Pfizer; Roche; Tesaro
Research Funding - Tesaro
Travel, Accommodations, Expenses - Novartis; Roche; Tesaro

Clinical activity of MCLA-128 (zenocutuzumab), trastuzumab, and vinorelbine in HER2 amplified metastatic breast cancer (MBC) patients (pts) who had progressed on anti-HER2 ADCs.
 
Erika Paige Hamilton
Consulting or Advisory Role - AstraZeneca (Inst); Black Diamond Therapeutics (Inst); Boehringer Ingelheim (Inst); Daiichi Sankyo (Inst); Genentech/Roche (Inst); Lilly (Inst); Mersana (Inst); Novartis (Inst); Pfizer (Inst); Puma Biotechnology (Inst); Silverback Therapeutics (Inst)
Research Funding - Abbvie (Inst); Acerta Pharma (Inst); Aravive (Inst); ArQule (Inst); Arvinas (Inst); AstraZeneca (Inst); BerGenBio (Inst); Black Diamond Therapeutics (Inst); Boehringer Ingelheim (Inst); Clovis Oncology (Inst); Compugen (Inst); Curis (Inst); CytomX Therapeutics (Inst); Daiichi Sankyo (Inst); Deciphera (Inst); eFFECTOR Therapeutics (Inst); Eisai (Inst); EMD Serono (Inst); Fochon Pharmaceuticals (Inst); Fujifilm (Inst); G1 Therapeutics (Inst); Genentech/Roche (Inst); H3 Biomedicine (Inst); Harpoon (Inst); Hutchison MediPharma (Inst); Immunomedics (Inst); InventisBio (Inst); Karyopharm Therapeutics (Inst); Leap Therapeutics (Inst); Lilly (Inst); Lycera (Inst); Macrogenics (Inst); MedImmune (Inst); Medivation (Inst); Mersana (Inst); Merus (Inst); Millennium (Inst); Molecular Templates (Inst); Novartis (Inst); Nucana (Inst); OncoMed (Inst); Orinove (Inst); Pfizer (Inst); Puma Biotechnology (Inst); Radius Health (Inst); Regeneron (Inst); Rgenix (Inst); Seagen (Inst); Sermonix Pharmaceuticals (Inst); Silverback Therapeutics (Inst); Stem CentRx (Inst); Sutter Medical Group (Inst); Syndax (Inst); Syros Pharmaceuticals (Inst); Taiho Pharmaceutical (Inst); Takeda (Inst); TapImmune Inc. (Inst); Tesaro (Inst); Torque (Inst); Torque (Inst); Unum Therapeutics (Inst); Verastem (Inst); Zenith Epigenetics (Inst); Zymeworks (Inst)
Travel, Accommodations, Expenses - Amgen; AstraZeneca; Bayer; Bristol-Myers Squibb; Clovis Oncology; Eisai; EMD Serono; Foundation Medicine; Genentech; Genentech/Roche; Genzyme; Guardant Health; Helsinn Therapeutics; HERON; Lexicon; Lilly; Lilly; Medivation; Merck; Novartis; Pfizer; Roche; Sysmex; Tesaro
 
Thierry Petit
Consulting or Advisory Role - Ipsen; Lilly; Novartis; Pfizer
Travel, Accommodations, Expenses - Novartis; Novartis; Pfizer
 
Barbara Pistilli
Consulting or Advisory Role - Myriad Genetics; Novartis; Pierre Fabre; Puma Biotechnology
Research Funding - Merus (Inst); Pfizer (Inst); Puma Biotechnology (Inst)
Travel, Accommodations, Expenses - AstraZeneca; MSD Oncology; Novartis; Pfizer
 
Anthony Goncalves
Research Funding - Abbvie (Inst); AstraZeneca (Inst); Boehringer Ingelheim (Inst); Bristol-Myers Squibb (Inst); Cascadian Therapeutics (Inst); Lilly (Inst); Merus (Inst); MSD (Inst); Nektar (Inst); Novartis (Inst); Roche (Inst); Roche/Genentech (Inst); Sanofi/Aventis (Inst); Seagen (Inst)
Travel, Accommodations, Expenses - AstraZeneca; Novartis; Pfizer; Roche/Genentech
 
Ana Alexandra Ferreira
No Relationships to Disclose
 
Florence Dalenc
Travel, Accommodations, Expenses - Pfizer; Roche
 
Fatima Cardoso
Consulting or Advisory Role - Amgen; Astellas Pharma; AstraZeneca; Celgene; Daiichi Sankyo; Eisai; GE Healthcare; Genentech; GlaxoSmithKline; Macrogenics; Medscape; Merck Sharp & Dohme; Merus; Mundipharma; Mylan; Novartis; Pfizer; Pierre Fabre; Prime Oncology; Roche; Samsung Bioepis; Sanofi; Seagen; Teva
Travel, Accommodations, Expenses - AstraZeneca; Pfizer; Roche
 
Monica M. Mita
Research Funding - Seagen (Inst)
 
Vincent O. Dezentjé
No Relationships to Disclose
 
Luis Manso
No Relationships to Disclose
 
Stephanie L. Graff
Speakers' Bureau - OncLive
Research Funding - Boehringer Ingelheim (Inst); Celldex (Inst); Dana Farber Cancer Hospital (Inst); Genentech (Inst); GRAIL (Inst); Immunomedics (Inst); Innocrin Pharma (Inst); Lilly (Inst); Merus NV (Inst); Novartis (Inst); Odonate Therapeutics (Inst); TapImmune Inc. (Inst)
 
Francois Clement Bidard
Consulting or Advisory Role - AstraZeneca; Lilly; Pfizer
Speakers' Bureau - Amgen; Amgen; AstraZeneca; Novartis; Pfizer
Research Funding - Menarini Silicon Biosystems (Inst); Novartis (Inst); Pfizer (Inst); Roche (Inst)
Patents, Royalties, Other Intellectual Property - MSI and ESR1 detection by ddPCR (patents pending) (Inst)
Travel, Accommodations, Expenses - Amgen; AstraZeneca; Menarini Silicon Biosystems; Pfizer; Roche
 
Philippe Georges Aftimos
Honoraria - Roche; Synthon
Consulting or Advisory Role - Amcure; Amgen; Boehringer Ingelheim; G1 Therapeutics; Macrogenics; Novartis; Novartis; Radius Health; Roche; Servier
Travel, Accommodations, Expenses - Amgen; MSD Oncology; Pfizer; Roche Belgium
 
Santiago Escrivá
Consulting or Advisory Role - Pierre Fabre; Roche
Speakers' Bureau - Eisai; Pierre Fabre; Roche
Research Funding - Roche (Inst); Synthon (Inst)
Travel, Accommodations, Expenses - Daiichi Sankyo; Pierre Fabre; Roche
 
Noemia Afonso
No Relationships to Disclose
 
Ernesto Wasserman
Employment - Merus NV
Stock and Other Ownership Interests - Merus NV
 
Kees Bol
Employment - Merus NV
 
Viktoriya Stalbovskaya
Employment - Merus NV
 
Anastasia Vliet
Employment - Merus NV
 
Thomas Bachelot
Consulting or Advisory Role - AstraZeneca; MSD Oncology; Novartis; Pfizer; Roche; Seagen
Research Funding - AstraZeneca (Inst); Novartis (Inst); Roche (Inst)
Travel, Accommodations, Expenses - AstraZeneca; pfizer; Roche