The following represents disclosure information provided by authors of this abstract. The program committee has reviewed all presenting author disclosure reports, identified potential conflicts of interest, and implemented strategies to manage those areas of conflict, where appropriate. All relationships are considered compensated. Relationships are self-held unless otherwise noted. I = Immediate Family Member, Inst = My Institution
 
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Dabrafenib + trametinib combination therapy in pediatric patients with BRAF V600-mutant low-grade glioma: Safety and efficacy results.
 
Birgit Geoerger
Consulting or Advisory Role - AZD; Bayer; Boehringer Ingelheim; Merck KGaA (Inst); Roche/Genentech
 
Eric Bouffet
Research Funding - Bristol-Myers Squibb (Inst); Roche (Inst)
 
James A. Whitlock
Consulting or Advisory Role - Amgen; Jazz Pharmaceuticals; Shire
Research Funding - Daiichi Sankyo; Novartis
 
Christopher L. Moertel
Stock and Other Ownership Interests - OX2 Therapeutics
Patents, Royalties, Other Intellectual Property - Patents related to intellectual property held by OX2 Therapeutics and the University of Minnesota
 
Darren R. Hargrave
Consulting or Advisory Role - AstraZeneca; Bayer; Boehringer Ingelheim; Janssen; Novartis; PureTech; Roche/Genentech
Research Funding - AstraZeneca
Expert Testimony - AstraZeneca
Travel, Accommodations, Expenses - AstraZeneca; Boehringer Ingelheim; Novartis; Roche/Genentech
Other Relationship - Abbvie; AstraZeneca/MedImmune; Bristol-Myers Squibb; Celgene; Epizyme; Janssen; Novartis
 
Isabelle Aerts
Travel, Accommodations, Expenses - Bayer; Jazz Pharmaceuticals; Roche
 
Kenneth J. Cohen
Consulting or Advisory Role - Bristol-Myers Squibb; DNAtrix; Novartis
Research Funding - Bristol-Myers Squibb; Novartis
 
Lindsay Baker Kilburn
Employment - Kaiser Permanente (I)
Consulting or Advisory Role - Roche/Genentech
Research Funding - Epizyme (Inst); Novartis (Inst)
 
Karen D. Wright
Honoraria - Takeda
Consulting or Advisory Role - Boehringer Ingelheim; Grand Rounds; InfiniteMD
Research Funding - Takeda (Inst)
Travel, Accommodations, Expenses - Takeda
(OPTIONAL) Uncompensated Relationships - Boehringer Ingelheim; Day One Therapeutics; Takeda
 
Jeea Choi
Employment - Novartis
 
Eduard Gasal
Employment - Novartis
Stock and Other Ownership Interests - Novartis
Travel, Accommodations, Expenses - Novartis
 
Mark W. Russo
Employment - Novartis
Stock and Other Ownership Interests - Novartis
 
Elizabeth Fox
Research Funding - Ignyta (Inst); Novartis (Inst)
Other Relationship - Helsinn Therapeutics