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A phase I/II first-in-human study of a novel anti-MAGE-A4 TCR/anti-CD3 bispecific (IMC-C103C) as monotherapy and in combination with atezolizumab in HLA-A*02:01-positive patients with MAGE-A4-positive advanced solid tumors (IMC-C103C-101). |
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George R. Blumenschein, Jr. |
Employment - Janssen (I); Johnson & Johnson (I) |
Stock and Other Ownership Interests - Virogin Biotech |
Consulting or Advisory Role - Abbvie; Adicet Bio; Amgen; ARIAD; AstraZeneca; Bayer; Bristol-Myers Squibb; Celgene; Clovis Oncology; Genentech; Johnson & Johnson (I); Maverick Therapeutics; MedImmune; Merck; Novartis; Roche; Virogin Biotech; Xcovery |
Research Funding - Adaptimmune; AstraZeneca; Bayer; Bristol-Myers Squibb; Celgene; Exelixis; Genentech; GlaxoSmithKline; Immatics; Immunocore; Incyte; Kite, a Gilead company; Macrogenics; MedImmune; Merck; Novartis; Roche; Tmunity Therapeutics, Inc.; Torque; Xcovery |
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Honoraria - Array BioPharma; Immunocore; Instil Bio; Instil Bio; Merck; Tesaro; Vedanta Biosciences |
Consulting or Advisory Role - Instil Bio; Merck |
Research Funding - Bristol-Myers Squibb; CellSight Technologies; CellSight Technologies; Checkmate Pharmaceuticals; medpacto; Merck; Tesaro |
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Research Funding - Immunocore (Inst); Immunocore (Inst) |
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Consulting or Advisory Role - Aduro Biotech; Amgen; AstraZeneca/MedImmune; Bristol-Myers Squibb; CStone Pharmaceuticals; GlaxoSmithKline; Gritstone Bio; Immunocore; Kyn therapeutics; Pieris Pharmaceuticals; PsiOxus Therapeutics; PureTech; Roche/Genentech; Synlogic; TRM Oncology |
Research Funding - AstraZeneca; Bristol-Myers Squibb; Immunocore; Incyte; Merck; Pfizer; Roche/Genentech |
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Consulting or Advisory Role - Abbvie (Inst); Achilles Therapeutics (Inst); Association of Community Cancer Centers (ACCC) (Inst); Astellas Pharma (I); AstraZeneca (Inst); Atreca (Inst); Boehringer Ingelheim (Inst); Calithera Biosciences (Inst); Genentech/Roche (Inst); GlaxoSmithKline (Inst); Gritstone Bio (Inst); Guardant Health (Inst); Incyte (Inst); Janssen Oncology (Inst); Lilly (Inst); Loxo (Inst); Merck (Inst); Mirati Therapeutics (Inst); Novartis (Inst); Otsuka (I); Pfizer (Inst); Ribon Therapeutics (Inst); Sanofi (Inst) |
Research Funding - Abbvie (Inst); Acerta Pharma (Inst); Adaptimmune (Inst); Amgen (Inst); Apexigen (Inst); Arcus Biosciences (Inst); Array BioPharma (Inst); AstraZeneca (Inst); Atreca (Inst); BeiGene (Inst); Birdie (Inst); Boehringer Ingelheim (Inst); Checkpoint Therapeutics (Inst); Corvus Pharmaceuticals (Inst); CytomX Therapeutics (Inst); Daiichi Sankyo (Inst); Dynavax Technologies (Inst); EMD Serono (Inst); Genentech/Roche (Inst); Genmab (Inst); Genocea Biosciences (Inst); GlaxoSmithKline (Inst); Gritstone Bio (Inst); Guardant Health (Inst); Hengrui Pharmaceutical (Inst); Immunocore (Inst); Incyte (Inst); Janssen (Inst); Jounce Therapeutics (Inst); Kadmon (Inst); Lilly (Inst); Loxo (Inst); Lycera (Inst); Merck (Inst); Mirati Therapeutics (Inst); Neovia Oncology (Inst); Novartis (Inst); OncoMed (Inst); Pfizer (Inst); Regeneron (Inst); Ribon Therapeutics (Inst); Sanofi (Inst); Shattuck Labs (Inst); Stem CentRx (Inst); Syndax (Inst); Takeda (Inst); Tarveda Therapeutics (Inst); TCR2 Therapeutics (Inst); University of Michigan (Inst); WindMIL (Inst) |
Travel, Accommodations, Expenses - Abbvie; Astellas Pharma; AstraZeneca; Boehringer Ingelheim; Bristol-Myers Squibb; Clovis Oncology; Daiichi Sankyo; EMD Serono; Exelixis; Genentech; Incyte; Janssen Oncology; Lilly; Merck; Novartis; Pfizer; Sanofi; Sysmex; Vapotherm |
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Employment - Immunocore; MedImmune |
Leadership - Immunocore; MedImmune |
Stock and Other Ownership Interests - Immunocore; MedImmune |
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No Relationships to Disclose |