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ENGOT-OV44/FIRST study: a randomized, double-blind, adaptive, phase III study of standard of care (SOC) platinum-based therapy ± dostarlimab followed by niraparib ± dostarlimab maintenance as first-line (1L) treatment of stage 3 or 4 ovarian cancer (OC). |
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Anne-Claire Hardy-Bessard |
Consulting or Advisory Role - AstraZeneca; Novartis; Pfizer; Roche; Tesaro |
Travel, Accommodations, Expenses - Roche; Tesaro |
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Honoraria - Prime Oncology; Research To Practice |
Consulting or Advisory Role - Abbvie; Aravive; AstraZeneca (Inst); Clovis Oncology; Eisai; Genentech/Roche; Immunogen; Janssen Oncology; Merck; Mersana (Inst); OncoMed; Pfizer/EMD Serono; Samumed; TESARO (Inst); Vavotar Life Sciences; VBL Therapeutics |
Research Funding - Abbvie/Stemcentrx (Inst); Advaxis (Inst); Agenus (Inst); AstraZeneca (Inst); Bayer (Inst); Bristol-Myers Squibb (Inst); Clovis Oncology (Inst); Forty Seven (Inst); Genentech (Inst); Immunogen (Inst); Lilly (Inst); Lilly Foundation (Inst); Merck (Inst); Novartis Pharmaceuticals UK Ltd. (Inst); Novogen (Inst); PTC Therapeutics (Inst); Regeneron (Inst); Stem CentRx (Inst); Takeda (Inst); Tesaro (Inst); Verastem (Inst) |
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Leadership - Karyopharm Therapeutics; SeraCare |
Stock and Other Ownership Interests - Karyopharm Therapeutics; SeraCare |
Honoraria - Advaxis; AstraZeneca; Cerulean Pharma; Clovis Oncology; Novocure; Pfizer; Roche; tesaro |
Consulting or Advisory Role - AstraZeneca; BioCad; Cerulean Pharma; Clovis Oncology; Genmab; Karyopharm Therapeutics; Novocure; Pfizer; Sotio; Tesaro |
Research Funding - AstraZeneca (Inst); Boehringer Ingelheim (Inst); Clovis Oncology (Inst); Pfizer (Inst); Tesaro (Inst) |
Travel, Accommodations, Expenses - AstraZeneca; Karyopharm Therapeutics; Pfizer; Roche; SeraCare; Tesaro |
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Honoraria - AstraZeneca; Ipsen; Roche; SERVIER |
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Consulting or Advisory Role - Amgen; AstraZeneca; Clovis Oncology; GlaxoSmithKline; PharmaMar; Roche |
Research Funding - Eisai (Inst); Pharmamar (Inst); Roche (Inst) |
Travel, Accommodations, Expenses - AstraZeneca; PharmaMar; Roche |
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Honoraria - Amgen; AstraZeneca; Clovis Oncology; MSD Oncology; Roche Pharma AG; Tesaro |
Consulting or Advisory Role - AstraZeneca; Clovis Oncology; MSD Oncology; Roche Pharma AG; Tesaro |
Research Funding - Roche Pharma AG (Inst); Roche Pharma AG (Inst); Tesaro (Inst) |
Travel, Accommodations, Expenses - Roche Pharma AG; Tesaro |
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Honoraria - AstraZeneca; MSD; pfizer; pharmamar; Roche; Tesaro |
Consulting or Advisory Role - AstraZeneca; Pfizer; PharmaMar; Roche; tesaro |
Research Funding - AstraZeneca (Inst); MSD (Inst); Pfizer (Inst); Roche (Inst) |
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Honoraria - AstraZeneca; Roche/Genentech |
Consulting or Advisory Role - AstraZeneca |
Travel, Accommodations, Expenses - Roche/Genentech |
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Consulting or Advisory Role - AstraZeneca; Roche; Sotio |
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No Relationships to Disclose |
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Honoraria - Clovis Oncology |
Consulting or Advisory Role - AstraZeneca; Clovis Oncology; Clovis Oncology; Clovis Oncology; Clovis Oncology; immunogen; Roche; Sotio; Tesaro; Tesaro; Tesaro |
Research Funding - AstraZeneca (Inst); Boehringer Ingelheim (Inst); Clovis Oncology (Inst); Ignyta (Inst); Immunogen (Inst); Pfizer (Inst); Roche (Inst); Tesaro (Inst) |
Travel, Accommodations, Expenses - AstraZeneca; Roche; TESARO |
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Honoraria - Amgen; AstraZeneca; Genesis Pharma; Merck; MSD; Novartis; Roche |
Consulting or Advisory Role - Amgen; AstraZeneca; Genesis Pharma; Merck; MSD; Novartis; Roche |
Research Funding - Bristol-Myers Squibb; Roche |
Expert Testimony - Bristol-Myers Squibb; Roche |
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No Relationships to Disclose |
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No Relationships to Disclose |
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Consulting or Advisory Role - CUE Biopharma; Genentech/Roche; Inovio Pharmaceuticals; Merck; Morphotek; Tesaro |
Research Funding - Abbvie (Inst); Aduro Biotech (Inst); Advaxis (Inst); Aeterna Zentaris (Inst); Bristol-Myers Squibb (Inst); Cerulean Pharma (Inst); Cerulean Pharma (Inst); Genentech/Roche (Inst); GlaxoSmithKline (Inst); Leap Therapeutics (Inst); Ludwig Institute for Cancer Research (Inst); Merck (Inst); Millennium (Inst); Morab (Inst); Morphotek (Inst); Novartis (Inst); Pfizer (Inst); Syndax (Inst); Syndax (Inst); Tesaro (Inst) |
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Consulting or Advisory Role - AstraZeneca; Clovis Oncology; Deep 6 AI; Genentech/Roche; Tesaro |
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Employment - GlaxoSmithKline |
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Employment - GlaxoSmithKline |
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Honoraria - AstraZeneca; GlaxoSmithKline; Tesaro |
Consulting or Advisory Role - AstraZeneca; Clovis Oncology; Incyte; Merck; Pfizer/EMD Serono; Roche; TESARO |
Travel, Accommodations, Expenses - AstraZeneca; Roche; Tesaro |
Other Relationship - Arcagy-Gineco |