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Evaluation of predictive biomarkers for nivolumab in patients (pts) with metastatic clear cell renal cell carcinoma (mccRCC) from the CheckMate-025 (CM-025) trial. |
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No Relationships to Disclose |
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No Relationships to Disclose |
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No Relationships to Disclose |
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No Relationships to Disclose |
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Honoraria - LM Education/Exchange Service |
Consulting or Advisory Role - Adept Field Solutions; Blueprint Partnership; Bristol-Myers Squibb; Charles River Associates; Dedham Group; Defined Health; Insight Strategy; Octane Co.; Schlesinger Associates; Slingshot Insights; Trinity Group |
Travel, Accommodations, Expenses - Bristol-Myers Squibb |
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Employment - ApotheCom (I); Bristol-Myers Squibb |
Stock and Other Ownership Interests - Bristol-Myers Squibb |
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Employment - Pyramid Consulting Group |
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Consulting or Advisory Role - Lilly |
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No Relationships to Disclose |
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Stock and Other Ownership Interests - ervaxx; Genome Medical; Microsoft; Syapse; Tango Therapeutics |
Consulting or Advisory Role - ervaxx; Genome Medical; Illumina; InVitae; Janssen; Novartis; Roche; Syapse; Takeda; Tango Therapeutics; Third Rock Ventures |
Speakers' Bureau - Illumina |
Research Funding - Bristol-Myers Squibb; Novartis |
Patents, Royalties, Other Intellectual Property - Patent on clinical interpretation algorithms using cancer molecular data (Inst); Patent on discovery of chromatin regulators as biomarkers of response to cancer immunotherapy (Inst); Patent on discovery of retained intron as source of cancer neoantigens (Inst) |
Travel, Accommodations, Expenses - Roche/Genentech |
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Honoraria - Bristol-Myers Squibb |
Consulting or Advisory Role - Adaptimmune (I); Elpiscience (I); Elstar Therapeutics (I); ITeos Therapeutics; Jubilant Therapeutics; Monopteros Therapeutics (I); Monopteros Therapeutics (I); Nextpoint; Origimed; Selecta Biosciences (I); SQZ Biotech (I); Surface Oncology (I); Triursus Therapeutics; Xios Therapeutics |
Research Funding - Bristol-Myers Squibb; Ipsen (I); Merck Sharp & Dohme (I); Novartis (I); Quark (I); Roche/Genentech (I); UCB (I) |
Patents, Royalties, Other Intellectual Property - Amplimmune/Astrazeneca; Boehringer Ingelheim; Bristol-Myers Squibb/Medarex; Dako; EMD Serono; Leica Biosystems; Mayo Clinic; Merck; Novartis; Novartis (I); Pfizer (I); Pfizer (I); Roche/Genentech; Roche/Genentech (I) |
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Consulting or Advisory Role - Adaptimmune; BB Biotech Ventures; Bristol-Myers Squibb; Elpiscience; Elstar Therapeutics; igm; ITeos Therapeutics; Jubilant Pharmaceuticals; Monopteros Therapeutics; NextPoint; Origimed; Roche; Selecta Biosciences; SQZ Biotech; Surface Oncology; Triursus Therapeutics; Xios Therapeutics |
Research Funding - Bristol-Myers Squibb; Ipsen; Merck; Novartis; Quark; Roche; UCB |
Patents, Royalties, Other Intellectual Property - AstraZeneca; Boehringer Ingelheim; Bristol-Myers Squibb; DAKO; Leica Biosystems; Mayo Clinic; Merck; Merck Serono; Novartis; Pfizer; Roche |
Other Relationship - Journal of Experimental Medicine |
(OPTIONAL) Uncompensated Relationships - Novartis |
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Employment - Dana-Farber Cancer Institute |
Stock and Other Ownership Interests - Apricity Health; Torque |
Consulting or Advisory Role - 7 Hills Pharma; Aduro Biotech; Amgen; Bayer; Boston Pharmaceuticals; Bristol-Myers Squibb; Compass Therapeutics; EMD Serono; Genentech/Roche; Merck Sharp & Dohme; Novartis; Partners Therapeutics; Pfizer; Pionyr; Rheos Medicines; Sanofi; Surface Oncology; Takeda; Torque; Verastem |
Research Funding - bristol-myers squibb (Inst); Genentech/Roche (Inst); Merck Sharp & Dohme (Inst); novartis (Inst) |
Patents, Royalties, Other Intellectual Property - Angiopoietin-2 Biomarkers Predictive of Anti-immune checkpoint response (Inst); Compositions and Methods for Identification, Assessment, Prevention, and Treatment of Melanoma using PD-L1 Isoforms; Methods of Using Pembrolizumab and Trebananib (Inst); patent pending as per institutional policy; patent pending royalties received on MICA related disorders application to institution per institutional IP policy |
Travel, Accommodations, Expenses - Bristol-Myers Squibb; Novartis |
Other Relationship - Bristol-Myers Squibb; Genentech/Roche |
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Consulting or Advisory Role - Eisai; Exelixis; Genentech/Roche; Incyte; Lilly; Merck; Novartis; Pfizer |
Research Funding - Bristol-Myers Squibb (Inst); Eisai (Inst); Genentech/Roche (Inst); Novartis (Inst); Pfizer (Inst) |
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Stock and Other Ownership Interests - Neon Therapeutics; Neon Therapeutics (I) |
Research Funding - Pharmacyclics |
Patents, Royalties, Other Intellectual Property - Neon Therapeutics; Neon Therapeutics (I) |
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Consulting or Advisory Role - Agenus; Array BioPharma; Arrowhead Pharmaceuticals; Aveo; Bristol-Myers Squibb; Cota Healthcare; Eisai; Exelixis; Fathom Biotechnology; Genentech; Glactone Pharma; Immunocore; Iovance Biotherapeutics; Leads Biolabs; Merck; Neoleukin Therapeutics; Novartis; Oncolys BioPharma; Pfizer; Pneuma Respiratory; Pyxis; Surface Oncology; Werewolf Pharma; X4 Pharma |
Research Funding - Bristol-Myers Squibb (Inst) |
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Consulting or Advisory Role - alkermes; Array BioPharma; Bristol-Myers Squibb; EMD Serono; exelixis; Genentech/Roche; Jounce Therapeutics; Lilly; Merck; Novartis; Peloton Therapeutics; Pfizer |
Research Funding - alkermes (Inst); Bristol-Myers Squibb (Inst); Genentech (Inst); Merck (Inst); Novartis (Inst); Peloton Therapeutics (Inst); Prometheus (Inst) |
Other Relationship - Beth Israel Deaconess Medical Center |
(OPTIONAL) Uncompensated Relationships - AVEO; X4 Pharma |
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Stock and Other Ownership Interests - Agenus; Agios; BreakBio Corp.; Bristol-Myers Squibb; Newlink Genetics |
Patents, Royalties, Other Intellectual Property - Dana Farber Cancer Hospital |
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Employment - Dana Farber Cancer Hospital |
Leadership - ASCO; Dana Farber Cancer Hospital; Kidney Cancer Association; KidneyCan; NCCN |
Stock and Other Ownership Interests - Pionyr; Tempest Therapeutics |
Honoraria - Alexion Pharmaceuticals; alligent; Analysis Group; ASCO; AstraZeneca; Bayer; Bristol-Myers Squibb; Cerulean Pharma; Clinical Care Options; Corvus Pharmaceuticals; Eisai; EMD Serono; Exelixis; Foundation Medicine; Genentech/Roche; GlaxoSmithKline; Harborside Press; HERON; Ipsen; Kidney Cancer Association; Lancet Oncology; Lilly; Lpath; Merck; Michael J. Hennessy Associates; Navinata Health; NCCN; Novartis; Peloton Therapeutics; Pfizer; PlatformQ Health; Prometheus; Sanofi/Aventis; The New England Journal of Medicine; UpToDate |
Consulting or Advisory Role - Alexion Pharmaceuticals; alligent; Analysis Group; ASCO; AstraZeneca; Bayer; Bristol-Myers Squibb; Cerulean Pharma; Clinical Care Options; Corvus Pharmaceuticals; Eisai; EMD Serono; ESMO; Exelixis; Foundation Medicine; GlaxoSmithKline; Harborside Press; HERON; Ipsen; Kidney Cancer Association; Lancet Oncology; Lilly; Lpath; Merck; Michael J. Hennessy Associates; Navinata Health; NCCN; Novartis; Peloton Therapeutics; Pfizer; PlatformQ Health; Prometheus; Roche/Genentech; Sanofi/Aventis; The New England Journal of Medicine; UpToDate |
Research Funding - Agensys (Inst); Analysis Group (Inst); AstraZeneca (Inst); Bayer (Inst); Bristol-Myers Squibb (Inst); Calithera Biosciences (Inst); Celldex (Inst); Cerulean Pharma (Inst); Congressionally Directed Medical Research Programs (DOD) (Inst); Corvus Pharmaceuticals (Inst); Eisai (Inst); Exelixis (Inst); Foundation Medicine (Inst); Gateway for Cancer Research (Inst); GlaxoSmithKline (Inst); Ipsen (Inst); Merck (Inst); NCI (Inst); Novartis (Inst); Peloton Therapeutics (Inst); Pfizer (Inst); Prometheus (Inst); Roche (Inst); Roche/Genentech (Inst); Seattle Genetics/Astellas (Inst); Takeda (Inst); TRACON Pharma (Inst) |
Patents, Royalties, Other Intellectual Property - -International Patent Application No. PCT/US2018/058430, entitled “Biomarkers of Clinical Response and Benefit to Immune Checkpoint Inhibitor Therapy; International Patent Application No. PCT/US2018/12209, entitled “PBRM1 Biomarkers Predictive of Anti-Immune Checkpoint Response |
Travel, Accommodations, Expenses - Alexion Pharmaceuticals; alligent; Analysis Group; AstraZeneca; Bayer; Bristol-Myers Squibb; Cerulean Pharma; Clinical Care Options; Corvus Pharmaceuticals; Eisai; EMD Serono; ESMO; Exelixis; Foundation Medicine; GlaxoSmithKline; Harborside Press; HERON; Ipsen; Kidney Cancer Association; Lancet Oncology; Lilly; Lpath; Merck; Michael J. Hennessy Associates; Navinata Health; NCCN; Novartis; Peloton Therapeutics; Pfizer; PlatformQ Health; Prometheus; Roche/Genentech; Sanofi/Aventis; The New England Journal of Medicine; UpToDate |
Other Relationship - Medical writing and editorial assistance support may have been funded by Communications companies funded by pharmaceutical companies such as ClinicalThinking, Health Interactions, Envision Pharma Group, Fishawack Group of Companies, Parexel |
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Consulting or Advisory Role - AstraZeneca/MedImmune; Bristol-Myers Squibb; Merck |
Research Funding - AstraZeneca (Inst); Bristol-Myers Squibb (Inst); Exelixis (Inst); Novartis (Inst) |
Patents, Royalties, Other Intellectual Property - Receives royalties from Biogenex |
Other Relationship - AACR; NCI |