The following represents disclosure information provided by authors of this abstract. The program committee has reviewed all presenting author disclosure reports, identified potential conflicts of interest, and implemented strategies to manage those areas of conflict, where appropriate. All relationships are considered compensated. Relationships are self-held unless otherwise noted. I = Immediate Family Member, Inst = My Institution
 
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First-in-human study of palcitoclax (APG-1252), a novel dual Bcl-2/Bcl-xL inhibitor, demonstrated advantages in platelet safety while maintaining anticancer effect in U.S. patients with metastatic solid tumors.
 
Nehal J. Lakhani
Consulting or Advisory Role - Innovent Biologics
Research Funding - Alexion Pharmaceuticals (Inst); Alexo Therapeutics (Inst); Apexian Pharmaceuticals (Inst); Asana Biosciences (Inst); Ascentage Pharma (Inst); BeiGene (Inst); Cerulean Pharma (Inst); Constellation Pharmaceuticals (Inst); Coordination Therapeutics (Inst); CytomX Therapeutics (Inst); Formation Biologics (Inst); Forty Seven (Inst); Incyte (Inst); InhibRx (Inst); Innovent Biologics (Inst); Jounce Therapeutics (Inst); Livzon (Inst); Loxo (Inst); Macrogenics (Inst); Merck (Inst); Northern Biologics (Inst); Pfizer (Inst); Regeneron (Inst); Symphogen (Inst); TaiRx, Inc. (Inst); Tesaro (Inst)
 
Drew W. Rasco
Research Funding - Abbvie (Inst); Apexian Pharmaceuticals (Inst); Asana Biosciences (Inst); Ascentage Pharma (Inst); Astex Pharmaceuticals (Inst); Celgene (Inst); Compugen (Inst); Constellation Pharmaceuticals (Inst); Coordination Therapeutics (Inst); Eisai (Inst); Five Prime Therapeutics (Inst); GlaxoSmithKline (Inst); Gossamer Bio (Inst); Incyte (Inst); Macrogenics (Inst); Merck (Inst); Seven and Eight Biopharmaceuticals (Inst); Syndax (Inst)
Travel, Accommodations, Expenses - Asana Biosciences
 
Qi Zeng
Employment - Ascentage Pharma
 
Yuefen Tang
Employment - Ascentage Pharma
 
ZHIYAN LIANG
Employment - Ascentage Pharma
 
Hengbang Wang
Employment - Ascentage Pharma
 
Ming Lu
Employment - Ascentage Pharma
 
Jason Chen
Employment - Ascentage Pharma
 
Lei Fu
Employment - Ascentage Pharma
 
Cunlin Wang
Employment - Ascentage Pharma
 
Dajun Yang
Employment - Ascentage Pharma; Ascentage Pharma; Ascentage Pharma
Leadership - Ascentage Pharma; Ascentage Pharma; Ascentage Pharma
Stock and Other Ownership Interests - Ascentage Pharma
 
Yifan Zhai
Employment - Ascentage Pharma; Ascentage Pharma; HealthQuest Pharma
Leadership - Ascentage Pharma; Ascentage Pharma; HealthQuest Pharma
Stock and Other Ownership Interests - Ascentage Pharma