The following represents disclosure information provided by authors of this abstract. The program committee has reviewed all presenting author disclosure reports, identified potential conflicts of interest, and implemented strategies to manage those areas of conflict, where appropriate. All relationships are considered compensated. Relationships are self-held unless otherwise noted. I = Immediate Family Member, Inst = My Institution
 
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A phase I, first-in-human, open-label, dose-escalation, safety, pharmacokinetic, and pharmacodynamic study of oral TP-3654 administered daily for 28 days to patients with advanced solid tumors.
 
Ignacio Garrido-Laguna
Consulting or Advisory Role - Array BioPharma; Eisai
Research Funding - ARMO BioSciences (Inst); Bayer (Inst); Bristol-Myers Squibb (Inst); GlaxoSmithKline (Inst); Glenmark (Inst); Halozyme (Inst); Ignyta (Inst); Incyte (Inst); Lilly (Inst); MedImmune (Inst); Newlink Genetics (Inst); Novartis (Inst); OncoMed (Inst); Pfizer (Inst)
 
Patrick Michael Dillon
Research Funding - Abbvie (Inst); Merck (Inst); Nektar (Inst); Newlink Genetics (Inst); Novartis (Inst); Pfizer (Inst); Tesaro (Inst); Tolero Pharmaceuticals (Inst)
 
Stephen Patrick Anthony
Employment - Tolero Pharmaceuticals
Patents, Royalties, Other Intellectual Property - Tolero Pharmaceuticals
Travel, Accommodations, Expenses - Tolero Pharmaceuticals
 
Margit Janat-Amsbury
Employment - Tolero Pharmaceuticals
Patents, Royalties, Other Intellectual Property - Tolero Pharmaceuticals
Travel, Accommodations, Expenses - Tolero Pharmaceuticals
 
Nissa Ashenbramer
Employment - Tolero Pharmaceuticals
 
Steven L Warner
Employment - Tolero Pharmaceuticals
Leadership - Tolero Pharmaceuticals
Patents, Royalties, Other Intellectual Property - Tolero Pharmaceuticals
 
Lars Mouritsen
Employment - Tolero Pharmaceuticals
 
Mark L. Wade
Employment - Tolero Pharmaceuticals
Stock and Other Ownership Interests - Amgen
Travel, Accommodations, Expenses - Tolero Pharmaceuticals
 
Clifford Whatcott
Employment - Tolero Pharmaceuticals
Patents, Royalties, Other Intellectual Property - Tolero Pharmaceuticals
 
David Bearss
Patents, Royalties, Other Intellectual Property - Tolero Pharmaceuticals
Travel, Accommodations, Expenses - Tolero Pharmaceuticals
 
Siqing Fu
Research Funding - Abbisko (Inst); Anaeropharma (Inst); Arrien Pharmaceuticals (Inst); AstraZeneca (Inst); BeiGene (Inst); BioAtla (Inst); Boehringer Ingelheim (Inst); Hookipa Pharma (Inst); Huya Bioscience International (Inst); Immune Cell Therapy (Inst); Innovent Biologics (Inst); Lilly (Inst); Lyvgen Biopharma (Inst); MacroGenics (Inst); Medivir (Inst); Millennium (Inst); Nerviano Medical Sciences (Inst); NeuPharma, Inc. (Inst); NIH/NCI (Inst); Novartis (Inst); OncoMed (Inst); Parexel International, LLC (Inst); Sellas Life Sciences (Inst); Soricimed (Inst); Takeda (Inst); Tolero Pharmaceuticals (Inst)