The following represents disclosure information provided by authors of this abstract. The program committee has reviewed all presenting author disclosure reports, identified potential conflicts of interest, and implemented strategies to manage those areas of conflict, where appropriate. All relationships are considered compensated. Relationships are self-held unless otherwise noted. I = Immediate Family Member, Inst = My Institution
 
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A phase I, first-in-human, open-label, dose-escalation, safety, pharmacokinetic, and pharmacodynamic study of oral TP-1287 administered daily to patients with advanced solid tumors.
 
Ben George
Honoraria - Newlink Genetics
Consulting or Advisory Role - Bayer; Bristol-Myers Squibb; Celgene; Cook Medical; Eisai; Exelixis; Foundation Medicine; Ipsen; Merrimack; Taiho Pharmaceutical; TERUMO
Research Funding - Boehringer Ingelheim (Inst); CeGaT (Inst); Celgene (Inst); Eisai (Inst); Foundation Medicine (Inst); Roche (Inst); Roche/Genentech (Inst); Taiho Pharmaceutical (Inst)
 
Donald A. Richards
Consulting or Advisory Role - Ipsen; Seattle Genetics/Astellas; Taiho Pharmaceutical
 
William Jeffery Edenfield
Consulting or Advisory Role - Chimerix
 
Steven L Warner
Employment - Tolero Pharmaceuticals
Leadership - Tolero Pharmaceuticals
Patents, Royalties, Other Intellectual Property - Tolero Pharmaceuticals
 
Lars Mouritsen
Employment - Tolero Pharmaceuticals
 
Reyna Bishop
Employment - Tolero Pharmaceuticals
 
Stephen Patrick Anthony
Employment - Tolero Pharmaceuticals
Patents, Royalties, Other Intellectual Property - Tolero Pharmaceuticals
 
David Bearss
Employment - Tolero Pharmaceuticals
Leadership - Tolero Pharmaceuticals
Patents, Royalties, Other Intellectual Property - Tolero Pharmaceuticals
 
Nicholas J. Vogelzang
Employment - US Oncology
Stock and Other Ownership Interests - Caris Life Sciences
Honoraria - Novartis; Pfizer; UpToDate
Consulting or Advisory Role - Astellas Pharma; AstraZeneca; Bayer; Boehringer Ingelheim; Caris Life Sciences; Clovis Oncology; Corvus Pharmaceuticals; Eisai; Genentech/Roche; Janssen Oncology; Merck; Modra Pharmaceuticals; Pfizer; Tolero Pharmaceuticals
Speakers' Bureau - Bayer; Bristol-Myers Squibb; Genentech/Roche; Sanofi
Research Funding - Endocyte (Inst); Merck (Inst); Suzhou Kintor Pharmaceuticals (Inst); US Oncology (Inst)
Expert Testimony - Novartis
Travel, Accommodations, Expenses - AstraZeneca/MedImmune; Bayer/Onyx; Exelixis; Genentech/Roche; Pfizer; Sanofi/Aventis; US Oncology
 
Clifford Whatcott
Employment - Tolero Pharmaceuticals
Patents, Royalties, Other Intellectual Property - Tolero Pharmaceuticals