The following represents disclosure information provided by authors of this abstract. The program committee has reviewed all presenting author disclosure reports, identified potential conflicts of interest, and implemented strategies to manage those areas of conflict, where appropriate. All relationships are considered compensated. Relationships are self-held unless otherwise noted. I = Immediate Family Member, Inst = My Institution
 
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Management of adverse events in patients with HER2+ metastatic breast cancer treated with tucatinib, trastuzumab, and capecitabine (HER2CLIMB).
 
Alicia Frances Clare Okines
Stock and Other Ownership Interests - AstraZeneca (I)
Research Funding - Pfizer (Inst)
Travel, Accommodations, Expenses - LEO Pharma
 
Elisavet Paplomata
Honoraria - Mylan; Novartis; Pfizer; Radialogica
Consulting or Advisory Role - Mylan; Novartis; Pfizer; Radialogica
Research Funding - Abbvie (Inst); Cascadian Therapeutics (Inst); Corcept Therapeutics (Inst); Genentech (Inst); Hoosier Cancer Research Network (Inst); Merck (Inst); Novartis (Inst); Seagen (Inst)
Travel, Accommodations, Expenses - Amgen; Genentech; Merck; Novartis; Tesaro
 
Tanya A. Wahl
No Relationships to Disclose
 
Gail Lynn Shaw Wright
Stock and Other Ownership Interests - Macrogenics (I); Odonate Therapeutics; Puma Biotechnology; Roche
Research Funding - Abbvie; Astellas Pharma; AstraZeneca; Boehringer Ingelheim; Bristol-Myers Squibb; Celgene; E.R. Squibb Sons, LLC; G1 Therapeutics; Genentech; H3 Biomedicine; Incyte; Innocrin Pharma; Janssen; Lilly; Medivation; Novartis; Nucana; Pfizer; Seagen; Taiho Pharmaceutical; Tesaro
 
Stephanie Sutherland
Consulting or Advisory Role - Roche
Research Funding - Seagen (Inst)
 
Erik Jakobsen
Consulting or Advisory Role - Novartis; Pfizer; Roche
Travel, Accommodations, Expenses - Roche
 
Frances Valdes
Honoraria - Adverum (I); Allegro Ophthalmics (I); Allergan (I); BVI (I); EyePoint Pharmaceuticals (I); Genentech (I); Janssen Biotech (I); Novartis (I); Santen (I); Valeant Pharmaceuticals International (I)
Research Funding - Merck (Inst); Roche/Genentech (Inst)
 
Arlene Chan
Honoraria - Amgen; Eisai; Novartis
Consulting or Advisory Role - Lilly; Pfizer; Specialised Therapeutics
Speakers' Bureau - Prime Oncology
Research Funding - Eisai
Travel, Accommodations, Expenses - Amgen
 
Amy Sanders Clark
Consulting or Advisory Role - Novartis
Research Funding - Novartis (Inst)
 
Alison Katherine Conlin
Consulting or Advisory Role - bioTheranostics; Novartis; Pfizer; Seattle Genetics/Astellas
 
Maryam B. Lustberg
Consulting or Advisory Role - Disarm Therapeutics; PledPharma
Other Relationship - Cynosure/Hologic
 
Jennifer M. Specht
Honoraria - Daiichi Sankyo; Genomic Health; Nektar
Consulting or Advisory Role - Daiichi Sankyo; Genomic Health; Nektar
Research Funding - Cascadian Therapeutics (Inst); Genentech/Roche (Inst); Merck (Inst); Minerva Biotechnologies (Inst); Myriad Pharmaceuticals (Inst); Nektar (Inst); Novartis (Inst); Pfizer (Inst); Pfizer (Inst)
Travel, Accommodations, Expenses - Nektar
 
Timothy J. Pluard
Consulting or Advisory Role - Genentech; Macrogenics; Pfizer; Seagen
Speakers' Bureau - Genentech/Roche; Novartis; Pfizer; Tempus
Research Funding - Seagen (Inst)
 
Xiaofu Zhu
Consulting or Advisory Role - Amgen; Lilly; Novartis; Pfizer; Taiho Pharmaceutical
Travel, Accommodations, Expenses - Novartis; Taiho Pharmaceutical
 
Ian E. Krop
Employment - AMAG Pharmaceuticals (I)
Leadership - AMAG Pharmaceuticals (I)
Stock and Other Ownership Interests - AMAG Pharmaceuticals (I)
Honoraria - AstraZeneca; Celltrion; Genentech/Roche
Consulting or Advisory Role - Context Therapeutics; Daiichi Sankyo; Genentech/Roche; ION Pharma; Macrogenics; Merck; Novartis; Seagen; Taiho Pharmaceutical
Research Funding - Genentech (Inst); Pfizer (Inst)
 
Karen A. Gelmon
Honoraria - AstraZeneca; Merck Sharp & Dohme
Consulting or Advisory Role - AstraZeneca; Bristol-Myers Squibb; Genomic Health; Janssen Oncology; Lilly; Merck; Mylan; NanoString Technologies; Novartis; Pfizer; Roche
Research Funding - AstraZeneca (Inst); Bristol-Myers Squibb (Inst); Pfizer (Inst); Roche (Inst)
Expert Testimony - Genentech
 
Dennis J. Slamon
Leadership - Biomarin
Stock and Other Ownership Interests - Amgen; Amgen; BioMarin; Merck Sharp & Dohme; Pfizer; Seagen; Vertex
Honoraria - Novartis
Consulting or Advisory Role - Lilly; Novartis; Pfizer; Seagen
Speakers' Bureau - Novartis
Research Funding - Novartis; Pfizer
Travel, Accommodations, Expenses - Biomarin; Novartis; Pfizer; Pfizer
 
Jorge Ramos
Employment - Seagen
Stock and Other Ownership Interests - Seagen
 
Grace An
Employment - Novartis; Seagen
Stock and Other Ownership Interests - Seagen
 
Erika Paige Hamilton
Consulting or Advisory Role - AstraZeneca (Inst); Black Diamond Therapeutics (Inst); Boehringer Ingelheim (Inst); Daiichi Sankyo (Inst); Genentech/Roche (Inst); Lilly (Inst); Mersana (Inst); Novartis (Inst); Pfizer (Inst); Puma Biotechnology (Inst); Silverback Therapeutics (Inst)
Research Funding - Abbvie (Inst); Acerta Pharma (Inst); Aravive (Inst); ArQule (Inst); Arvinas (Inst); AstraZeneca (Inst); BerGenBio (Inst); Black Diamond Therapeutics (Inst); Boehringer Ingelheim (Inst); Clovis Oncology (Inst); Compugen (Inst); Curis (Inst); CytomX Therapeutics (Inst); Daiichi Sankyo (Inst); Deciphera (Inst); eFFECTOR Therapeutics (Inst); Eisai (Inst); EMD Serono (Inst); Fochon Pharmaceuticals (Inst); Fujifilm (Inst); G1 Therapeutics (Inst); Genentech/Roche (Inst); H3 Biomedicine (Inst); Harpoon (Inst); Hutchison MediPharma (Inst); Immunomedics (Inst); InventisBio (Inst); Karyopharm Therapeutics (Inst); Leap Therapeutics (Inst); Lilly (Inst); Lycera (Inst); Macrogenics (Inst); MedImmune (Inst); Medivation (Inst); Mersana (Inst); Merus (Inst); Millennium (Inst); Molecular Templates (Inst); Novartis (Inst); Nucana (Inst); OncoMed (Inst); Orinove (Inst); Pfizer (Inst); Puma Biotechnology (Inst); Radius Health (Inst); Regeneron (Inst); Rgenix (Inst); Seagen (Inst); Sermonix Pharmaceuticals (Inst); Silverback Therapeutics (Inst); Stem CentRx (Inst); Sutter Medical Group (Inst); Syndax (Inst); Syros Pharmaceuticals (Inst); Taiho Pharmaceutical (Inst); Takeda (Inst); TapImmune Inc. (Inst); Tesaro (Inst); Torque (Inst); Torque (Inst); Unum Therapeutics (Inst); Verastem (Inst); Zenith Epigenetics (Inst); Zymeworks (Inst)
Travel, Accommodations, Expenses - Amgen; AstraZeneca; Bayer; Bristol-Myers Squibb; Clovis Oncology; Eisai; EMD Serono; Foundation Medicine; Genentech; Genentech/Roche; Genzyme; Guardant Health; Helsinn Therapeutics; HERON; Lexicon; Lilly; Lilly; Medivation; Merck; Novartis; Pfizer; Roche; Sysmex; Tesaro