The following represents disclosure information provided by authors of this abstract. The program committee has reviewed all presenting author disclosure reports, identified potential conflicts of interest, and implemented strategies to manage those areas of conflict, where appropriate. All relationships are considered compensated. Relationships are self-held unless otherwise noted. I = Immediate Family Member, Inst = My Institution
 
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CONTESSA TRIO: A multinational, multicenter, phase (P) II study of tesetaxel (T) plus three different PD-(L)1 inhibitors in patients (Pts) with metastatic triple-negative breast cancer (TNBC) and tesetaxel monotherapy in elderly pts with HER2-metastatic breast cancer (MBC).
 
Sara M. Tolaney
Consulting or Advisory Role - Abbvie; AstraZeneca; Bristol-Myers Squibb; Celldex; Eisai; G1 Therapeutics; Genentech; Immunomedics; Lilly; Merck; NanoString Technologies; Nektar; Novartis; Odonate Therapeutics; Paxman; Pfizer; Puma Biotechnology; Sanofi; Seagen; Silverback Therapeutics
Research Funding - AstraZeneca (Inst); Bristol-Myers Squibb (Inst); Cyclacel (Inst); Eisai (Inst); Exelixis (Inst); Genentech/Roche (Inst); Immunomedics (Inst); Lilly (Inst); Merck (Inst); NanoString Technologies (Inst); Nektar (Inst); Novartis (Inst); Odonate Therapeutics (Inst); Pfizer (Inst)
Travel, Accommodations, Expenses - AstraZeneca; Celldex; Eisai; Genentech/Roche; Immunomedics; Lilly; Merck; NanoString Technologies; Nektar; Novartis; Pfizer; Puma Biotechnology
 
Igor Bondarenko
No Relationships to Disclose
 
Arlene Chan
Honoraria - Amgen; Eisai; Novartis
Consulting or Advisory Role - Lilly; Pfizer; Specialised Therapeutics
Speakers' Bureau - Prime Oncology
Research Funding - Eisai
Travel, Accommodations, Expenses - Amgen
 
Noshir Anthony Dacosta
No Relationships to Disclose
 
Yann Izarzugaza
Employment - Merck Serono (I)
Honoraria - Novartis; Roche/Genentech
Consulting or Advisory Role - Novartis
Travel, Accommodations, Expenses - Novartis; Pfizer
 
Gun Min Kim
No Relationships to Disclose
 
Mei-Ching Liu
Consulting or Advisory Role - AZD
Travel, Accommodations, Expenses - pfizer
 
Maria EVA Perez
Travel, Accommodations, Expenses - Pfizer (Inst)
 
Yen-Shen Lu
Honoraria - Lilly; Merck Sharp & Dohme; Novartis; Pfizer; Roche
Consulting or Advisory Role - Lilly; Novartis; Pfizer; Roche
Research Funding - Merck Sharp & Dohme (Inst); Novartis (Inst); Roche (Inst)
Travel, Accommodations, Expenses - Eisai; Novartis; Pfizer; Roche
 
Mafalda Oliveira
Honoraria - Novartis; Roche; Seagen
Consulting or Advisory Role - AstraZeneca; GlaxoSmithKline; Puma Biotechnology; Roche/Genentech; Seagen
Research Funding - AstraZeneca (Inst); Bayer (Inst); Boehringer Ingelheim (Inst); Cascadian Therapeutics (Inst); Celldex (Inst); GlaxoSmithKline (Inst); Immunomedics (Inst); Novartis (Inst); Philips Healthcare (Inst); Piqur (Inst); Puma Biotechnology (Inst); Roche/Genentech (Inst); Sanofi (Inst); Seagen (Inst); Zenith Epigenetics (Inst)
Travel, Accommodations, Expenses - Eisai; GP Pharm; Grunenthal; Novartis; Pierre Fabre; Roche
 
Samuel Guan Wei Ow
Honoraria - AstraZeneca; Lilly; Pfizer
 
Michel Pavic
Honoraria - Amgen; Celgene; Lilly; Novartis; Pfizer; Takeda
Travel, Accommodations, Expenses - Janssen
 
Hope S. Rugo
Consulting or Advisory Role - Celltrion; Ionis Pharmaceuticals
Research Funding - Daiichi Sankyo (Inst); Eisai (Inst); Genentech (Inst); Immunomedics (Inst); Lilly (Inst); Macrogenics (Inst); Merck (Inst); Novartis (Inst); OBI Pharma (Inst); Odonate Therapeutics (Inst); Pfizer (Inst); Seagen (Inst)
Travel, Accommodations, Expenses - Amgen; AstraZeneca; Daiichi Sankyo; Macrogenics; Merck; Mylan; Novartis; OBI Pharma; Pfizer; Puma Biotechnology
 
Lee S. Schwartzberg
Stock and Other Ownership Interests - Vector Oncology
Honoraria - Amgen; AstraZeneca; E.R. Squibb Sons, LLC; Genentech; Genomic Health; Helsinn Healthcare; Myriad Genetics; NanoString Technologies; Napo Pharmaceuticals; Novartis; Pfizer; Taiho Pharmaceutical
Consulting or Advisory Role - Abbvie; Amgen; AstraZeneca; Athenex; Biocept; bioTheranostics; Bristol-Myers Squibb; Caris Life Sciences; Coherus Biosciences; E.R. Squibb Sons, LLC; Genentech; Genomic Health; Helsinn Therapeutics; Lilly; Merck; Novartis; Pfizer; Roche; Spectrum Pharmaceuticals; Tesaro
Speakers' Bureau - Coherus Biosciences; Puma Biotechnology
Research Funding - Amgen (Inst); Bayer Health (Inst); E.R. Squibb Sons, LLC (Inst); E.R. Squibb Sons, LLC (Inst); Genentech (Inst); GlaxoSmithKline (Inst); Helsinn Therapeutics; MedImmune (Inst); Medivation (Inst); Novartis (Inst); Pfizer (Inst); Sanofi (Inst); Spectrum Pharmaceuticals (Inst); Tesaro (Inst)
 
Agostina Stradella
Consulting or Advisory Role - Roche
Speakers' Bureau - Eisai; Roche
Expert Testimony - Eisai; Roche
Travel, Accommodations, Expenses - Pfizer; Roche
 
Tira Jing Ying Tan
Stock and Other Ownership Interests - Immunomedics
Honoraria - AstraZeneca; Roche/Genentech
Consulting or Advisory Role - AstraZeneca; Lilly
Research Funding - AstraZeneca (Inst); Bayer (Inst); Novartis (Inst); Odonate Therapeutics (Inst); Synthon (Inst)
Travel, Accommodations, Expenses - AstraZeneca; Eisai
 
Vance Wright-Browne
Stock and Other Ownership Interests - Sun BioPharma
 
Joseph P. O'Connell
Employment - inVentiv Health; Odonate Therapeutics
Leadership - Odonate Therapeutics
Stock and Other Ownership Interests - inVentiv Health; Odonate Therapeutics
Travel, Accommodations, Expenses - inVentiv Health; Odonate Therapeutics
 
Thomas Wei
Employment - Odonate Therapeutics
Stock and Other Ownership Interests - Acorda Therapeutics; Allergan; Cardiome; HERON; MabVax; Mallinckrodt; Merck; NicOx; Pfizer
Patents, Royalties, Other Intellectual Property - I am listed as an inventor on patents for tesetaxel that have been assigned to Odonate Therapeutics. I receive no direct royalty income if these patents are issued. (Inst); I am listed as an inventor on patents for tesetaxel that have been assigned to Odonate Therapeutics. I receive no direct royalty income if these patents are issued. (Inst)
Travel, Accommodations, Expenses - Odonate Therapeutics
 
Elizabeth A. Mittendorf
Honoraria - Physicans' Education Resource
Consulting or Advisory Role - Genomic Health; Merck; Merck; Peregrine Pharmaceuticals; Sellas Life Sciences; TapImmune Inc.
Research Funding - AstraZeneca (Inst); EMD Serono (Inst); Galena Biopharma (Inst); Genentech/Roche (Inst); GlaxoSmithKline