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Evaluation of blood TMB (bTMB) in KEYNOTE-189: Pembrolizumab (pembro) plus chemotherapy (chemo) with pemetrexed and platinum versus placebo plus chemo as first-line therapy for metastatic nonsquamous NSCLC. |
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Honoraria - AstraZeneca/MedImmune; Bristol-Myers Squibb; GlaxoSmithKline; MSD Oncology; Roche; Takeda |
Consulting or Advisory Role - AstraZeneca; Bristol-Myers Squibb; Celgene; Daiichi Sankyo; Incyte; Inivata; Lilly; MSD; Novartis; Pfizer; Roche; Sanofi; Seagen; Takeda; Tiziana Life Sciences |
Speakers' Bureau - AstraZeneca; Bristol-Myers Squibb; Celgene; Incyte; Lilly; MSD Oncology; Otsuka; Roche; Takeda |
Research Funding - AstraZeneca (Inst); AstraZeneca/MedImmune (Inst); Blueprint Medicines; Bristol-Myers Squibb (Inst); GlaxoSmithKline (Inst); Incyte (Inst); Lilly (Inst); Merck (Inst); MSD (Inst); Novartis (Inst); Pfizer (Inst); Roche/Genentech (Inst); Spectrum Pharmaceuticals (Inst); Takeda (Inst) |
Travel, Accommodations, Expenses - AstraZeneca; Pfizer; Roche |
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Honoraria - AstraZeneca; Genentech/Roche; Merck |
Consulting or Advisory Role - AstraZeneca; Boehringer Ingelheim; Bristol-Myers Squibb; Genentech/Roche; Novocure; Takeda; Xcovery |
Research Funding - Aeglea Biotherapeutics (Inst); ARIAD/Takeda (Inst); Astellas Pharma (Inst); Blueprint Medicines (Inst); Daiichi Sankyo (Inst); G1 Therapeutics (Inst); Genentech/Roche (Inst); Lycera (Inst); Merck; Merck (Inst); Pfizer (Inst) |
Travel, Accommodations, Expenses - Genentech/Roche; Merck |
Other Relationship - AstraZeneca |
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Consulting or Advisory Role - Bristol-Myers Squibb; MSD; Roche |
Speakers' Bureau - Bristol-Myers Squibb; MSD; Roche |
Travel, Accommodations, Expenses - Bristol-Myers Squibb; MSD; Roche |
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No Relationships to Disclose |
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Travel, Accommodations, Expenses - Pfizer/EMD Serono; Pfizer/EMD Serono |
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No Relationships to Disclose |
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Honoraria - AstraZeneca; Boehringer Ingelheim; Bristol-Myers Squibb; MSD; Roche; Takeda |
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Consulting or Advisory Role - Bristol-Myers Squibb (Inst) |
Research Funding - Actuate Therapeutics (Inst); AstraZeneca/MedImmune (Inst); Bristol-Myers Squibb (Inst); Genentech/Roche (Inst); Incyte (Inst); Merck Sharp & Dohme (Inst); Novartis (Inst); Pfizer (Inst); Vyriad (Inst) |
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Consulting or Advisory Role - Dracen; EMD Serono; GlaxoSmithKline; Novartis |
Research Funding - AstraZeneca (Inst); Bristol-Myers Squibb (Inst); Dynavax Technologies (Inst); EMD Serono (Inst); Genentech (Inst); Iovance Biotherapeutics (Inst); Lilly (Inst); Merck (Inst); Mirati Therapeutics (Inst); Neon Therapeutics (Inst); Novartis (Inst) |
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Honoraria - AstraZeneca; Bristol-Myers Squibb; Lilly; Merck Sharp & Dohme; Novartis; Roche |
Consulting or Advisory Role - AstraZeneca; Bristol-Myers Squibb; Lilly; Merck Sharp & Dohme; Novartis; Roche |
Travel, Accommodations, Expenses - Novartis; Roche |
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No Relationships to Disclose |
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No Relationships to Disclose |
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No Relationships to Disclose |
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Stock and Other Ownership Interests - Merck |
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Stock and Other Ownership Interests - Merck |
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Stock and Other Ownership Interests - Merck |
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Employment - Merck Sharp & Dohme |
Stock and Other Ownership Interests - Merck Sharp & Dohme |
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Stock and Other Ownership Interests - Merck Sharp & Dohme |
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Stock and Other Ownership Interests - Merck |
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No Relationships to Disclose |