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BET inhibitor molibresib for the treatment of advanced solid tumors: Final results from an open-label phase I/II study. |
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No Relationships to Disclose |
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Leadership - Innate Pharma |
Honoraria - AstraZeneca; Bristol-Myers Squibb; MSD; PharmaMar; Roche |
Consulting or Advisory Role - Bayer; Blueprint Medicines; Deciphera; Pharmamar; Roche |
Research Funding - Bayer (Inst); GlaxoSmithKline (Inst); Novartis (Inst); Pharmamar (Inst); Roche (Inst) |
Travel, Accommodations, Expenses - Roche |
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No Relationships to Disclose |
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Honoraria - Astellas Pharma; AstraZeneca; BioExcel; Daiichi Sankyo; Genentech/Roche; Janssen Oncology; Menarini Silicon Biosystems; Pfizer; Sanofi; Sierra Oncology |
Consulting or Advisory Role - Astellas Pharma; AstraZeneca; Bayer; BioXCel therapeutics; Boehringer Ingelheim; Celgene; Daiichi Sankyo; Eisai; Genentech/Roche; Genmab; GlaxoSmithKline; Janssen Oncology; Menarini Silicon Biosystems; Merck Serono; Merck Sharp & Dohme; Orion; Pfizer; Sanofi; Sierra Oncology; Taiho Pharmaceutical |
Research Funding - Astex Pharmaceuticals (Inst); AstraZeneca (Inst); Bayer (Inst); Celgene (Inst); CellCentric (Inst); Daiichi Sankyo (Inst); Genentech (Inst); GlaxoSmithKline (Inst); MedImmune (Inst); Medivation (Inst); Merck Serono (Inst); Merck Sharp & Dohme (Inst); Orion (Inst); Sanofi (Inst); Sierra Oncology (Inst); Taiho Pharmaceutical (Inst) |
Patents, Royalties, Other Intellectual Property - Abiraterone Rewards to Inventors (Inst); CHK1 inhibitor (Inst); PARP inhibitors and DNA repair defects (Inst); Targeting of IL23 in prostate cancer (Inst) |
Travel, Accommodations, Expenses - Astellas Pharma; AstraZeneca; Genmab; GlaxoSmithKline; Orion; Qiagen; Sanofi; Taiho Pharmaceutical; Vertex |
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Honoraria - Bristol-Myers Squibb; Celgene; GlaxoSmithKline; Merck Serono; MSD; Nanobiotix; Novartis; Rakuten Medical; Roche |
Consulting or Advisory Role - Amgen; AstraZeneca; AstraZeneca; Bristol-Myers Squibb; GlaxoSmithKline; Merck Serono; MSD; Nanobiotix; Roche |
Travel, Accommodations, Expenses - AstraZeneca; Bristol-Myers Squibb; MSD |
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Consulting or Advisory Role - Bayer; Bristol-Myers Squibb; Janssen Oncology; Merck |
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Research Funding - Abbvie (Inst); ACEA Biosciences (Inst); Adaptimmune (Inst); Amgen (Inst); AstraZeneca (Inst); Bayer (Inst); BeiGene (Inst); Boehringer Ingelheim (Inst); Bristol-Myers Squibb (Inst); Celgene (Inst); E-therapeutics (Inst); Eisai (Inst); GlaxoSmithKline (Inst); Janssen (Inst); Menarini (Inst); Merck (Inst); Nanobiotix (Inst); Novartis (Inst); Pfizer (Inst); PharmaMar (Inst); PsiOxus Therapeutics (Inst); Puma Biotechnology (Inst); Regeneron (Inst); RigonTEC (Inst); Roche (Inst); Sanofi (Inst); Sierra Oncology (Inst); Synthon (Inst); Taiho Pharmaceutical (Inst); Takeda (Inst); Tesaro (Inst); Transgene (Inst) |
Expert Testimony - Medscape/Bayer; Nanobiotix |
Travel, Accommodations, Expenses - Sanofi/Regeneron |
Other Relationship - Bristol-Myers Squibb |
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Consulting or Advisory Role - Bristol-Myers Squibb; Eisai; MSD; Takeda |
Speakers' Bureau - AstraZeneca; Bayer; Eisai; MSD |
Travel, Accommodations, Expenses - Bristol-Myers Squibb; MSD |
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Consulting or Advisory Role - Abbvie; Ascentage Pharma; Bristol-Myers Squibb; Genentech/Roche |
Research Funding - Abbvie (Inst); Amgen (Inst); Bristol-Myers Squibb (Inst); GlaxoSmithKline (Inst); Merrimack (Inst) |
Travel, Accommodations, Expenses - Abbvie/Stemcentrx; AstraZeneca; Bristol-Myers Squibb; Bristol-Myers Squibb |
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Honoraria - Amgen; Astellas Pharma; Bayer; Janssen; Novartis; Pfizer; Telix Pharmaceuticals; Tolmar |
Consulting or Advisory Role - Astellas Pharma; AstraZeneca; Bristol-Myers Squibb; Janssen; Novartis; Pfizer; Sanofi; Telix Pharmaceuticals; Tolmar |
Speakers' Bureau - Amgen; Astellas Pharma; Bayer; Novartis |
Research Funding - Aptevo Therapeutics (Inst); Astellas Pharma; AstraZeneca (Inst); Bionomics (Inst); Bristol-Myers Squibb (Inst); GlaxoSmithKline (Inst); MedImmune (Inst); Merck Serono (Inst); Novartis (Inst); Pfizer (Inst); Sanofi (Inst); Synthorx (Inst) |
Travel, Accommodations, Expenses - Astellas Pharma; Merck Serono; Sanofi |
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Consulting or Advisory Role - Amgen; AstraZeneca; Eisai; Hanmi; Lilly; medpacto; Novartis; Pfizer; Roche/Genentech |
Research Funding - AstraZeneca; Pfizer; Roche/Genentech |
Travel, Accommodations, Expenses - Novartis; Roche/Genentech |
Other Relationship - Roche |
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Employment - GlaxoSmithKline |
Stock and Other Ownership Interests - GlaxoSmithKline; GlaxoSmithKline |
Travel, Accommodations, Expenses - GlaxoSmithKline |
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Employment - GlaxoSmithKline; Merck (I) |
Stock and Other Ownership Interests - GlaxoSmithKline; Merck |
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Employment - GlaxoSmithKline |
Stock and Other Ownership Interests - GlaxoSmithKline |
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Employment - GlaxoSmithKline |
Stock and Other Ownership Interests - GlaxoSmithKline |
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Employment - GlaxoSmithKline |
Stock and Other Ownership Interests - GlaxoSmithKline |
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Employment - GlaxoSmithKline; PRA Health Sciences (I) |
Stock and Other Ownership Interests - GlaxoSmithKline |
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Consulting or Advisory Role - Array BioPharma; Genentech |
Research Funding - Amgen; Array BioPharma (Inst); Bayer; BBI Healthcare; Bristol-Myers Squibb; Celgene; Five Prime Therapeutics; Forty Seven; Genentech; GlaxoSmithKline; H3 Biomedicine (Inst); Lilly/ImClone (Inst); Merck; Mirati Therapeutics; Novartis; Pfizer; Pharmacyclics; Taiho Pharmaceutical (Inst) |
Expert Testimony - Bayer; Lilly |
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Consulting or Advisory Role - Almac Diagnostics; Angiex; Artios; Astex Pharmaceuticals; Atrin Pharmaceuticals; Bayer; Bicycle Therapeutics; Boehringer Ingelheim; Boehringer Ingelheim; Concarlo; Cybrexa Therapeutics; Daiichi Sankyo; Fusion Pharmaceuticals; G1 Therapeutics; Ipsen; Lilly; Merck Serono; Pfizer; Roche; Seagen; Sierra Oncology |
Research Funding - Aileron Therapeutics (Inst); Amgen (Inst); Array BioPharma (Inst); AstraZeneca (Inst); AstraZeneca (Inst); Bayer (Inst); Boehringer Ingelheim (Inst); Bristol-Myers Squibb (Inst); CanBas (Inst); Cellceutix (Inst); Clovis Oncology (Inst); Covidien (Inst); Curis (Inst); Cyclacel (Inst); Esperas Pharma (Inst); Exelixis (Inst); Genentech (Inst); GlaxoSmithKline (Inst); Immune Design (Inst); Lilly (Inst); Merck (Inst); Merck Serono (Inst); Millennium (Inst); Mirati Therapeutics (Inst); Novartis (Inst); Pfizer (Inst); PharmaMar (Inst); PTC Therapeutics (Inst); Puma Biotechnology (Inst); Roche (Inst); Sanofi (Inst); Seagen (Inst); Sierra Oncology (Inst); Syros Pharmaceuticals (Inst); Tensha Therapeutics (Inst); Tesaro (Inst); Vertex (Inst) |
Patents, Royalties, Other Intellectual Property - Patent #: 9872874 Title: Dosage regimen for sapacitabine and seliciclib Issue Date: 1/23/2018; Provisional Patent #:62/538,319 Title: Compositions and methods for predicting response and resistance to CDK4/6 inhibition Filed: 7/28/17 |
Travel, Accommodations, Expenses - Bayer; Bicycle Therapeutics; G1 Therapeutics; Lilly; Pfizer; Sierra Oncology |
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Consulting or Advisory Role - Merck |
Research Funding - Abbvie (Inst); Alkermes (Inst); Aminex (Inst); Amphivena Therapetics, Inc. (Inst); Biomarin (Inst); Boehringer Ingelheim (Inst); Bristol-Myers Squibb (Inst); Cerulean Pharma (Inst); Chugai Pharma (Inst); Curis (Inst); Daiichi Sankyo (Inst); Five Prime Therapeutics (Inst); Genmab (Inst); GlaxoSmithKline (Inst); Helix BioPharma (Inst); Incyte (Inst); Jacobio (Inst); Lilly (Inst); MedImmune (Inst); Medivation (Inst); Merck Sharp and Dohme Corp. (Inst); New Link Genetics/BlueLink Pharmaceuticals (Inst); Novartis (Inst); Pfizer (Inst); Pieris Pharmaceuticals (Inst); Principa Biopharma (Inst); Puma Biotechnology (Inst); RAPT Therapeutics (Inst); Seagen (Inst); Taiho Pharmaceutical (Inst); Tesaro (Inst); TransThera Biosciences (Inst); XuanZhu (Inst) |