The following represents disclosure information provided by authors of this abstract. The program committee has reviewed all presenting author disclosure reports, identified potential conflicts of interest, and implemented strategies to manage those areas of conflict, where appropriate. All relationships are considered compensated. Relationships are self-held unless otherwise noted. I = Immediate Family Member, Inst = My Institution
 
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Safety profile of ripretinib, including impact of alopecia, and Palmar-Plantar Erythrodysesthesia Syndrome (PPES) on patient-reported outcomes (PROs), in ≥ fourth-line advanced gastrointestinal stromal tumors (GIST): Analyses from INVICTUS.

Suzanne  George

Stock and Other Ownership Interests  - Abbott Laboratories; Allergan (I)

Consulting or Advisory Role - Bayer; Blueprint Medicines; Daiichi Sankyo; deciphera; Lilly; MORE Health; Research to Practice; UpToDate

Research Funding - ARIAD (Inst); Bayer (Inst); Blueprint Medicines (Inst); Deciphera (Inst); Novartis (Inst); Pfizer (Inst)

Patents, Royalties, Other Intellectual Property - UptoDate

Expert Testimony - Bayer

Other Relationship - Research to Practice

Michael C.  Heinrich

Stock and Other Ownership Interests  - MolecularMD

Honoraria - Novartis

Consulting or Advisory Role - Blueprint Medicines; Deciphera; MolecularMD; Novartis

Patents, Royalties, Other Intellectual Property - Patent on treatment of GIST-licensed to Novartis (Inst)

Expert Testimony - Novartis

John Raymond  Zalcberg

Stock and Other Ownership Interests  - Aimmune; Alnylam; Biomarin; Bluebird Bio; Cochlear; CSL Limited; Dova Pharmaceuticals; GW Pharmaceuticals; Juno Therapeutics; Kiadis Pharma; Kite, a Gilead company; Sage Therapeutics; TherapeuticsMD; Vertex

Honoraria - Gilead Sciences; Halozyme; Merck Serono; pfizer; Specialised Therapeutics; Targovax

Consulting or Advisory Role - Halozyme; Lipotek; Merck Serono; Merck Sharp & Dohme; Pfizer; Sirtex Medical; Targovax

Research Funding - AstraZeneca (Inst); Baxalta/Shire (Inst); Bayer (Inst); Bristol-Myers Squibb (Inst); Lilly (Inst); Merck Serono (Inst); Pfizer (Inst); Roche (Inst); Specialised Therapeutics (Inst)

Travel, Accommodations, Expenses - AstraZeneca; Deciphera; Merck Serono; Merck Sharp & Dohme

Sebastian  Bauer

Honoraria - Bayer; GlaxoSmithKline; Novartis; Pfizer; Pharmamar

Consulting or Advisory Role - ADC Therapeutics; Bayer; Blueprint Medicines; Daiichi Sankyo; Deciphera; Exelixis; Janssen-Cilag; Janssen-Cilag; Lilly; Nanobiotix

Research Funding - Blueprint Medicines; Incyte (Inst); Novartis

Travel, Accommodations, Expenses - Pharmamar

Hans  Gelderblom

Patents, Royalties, Other Intellectual Property - Amgen, Boehringer-Ingelheim, Pfizer, Novartis, Pharmamar, Daiichi, Five Prime (Inst)

Patrick  Schoffski

Honoraria - Blueprint Medicines; Boehringer Ingelheim; Deciphera

Consulting or Advisory Role - Adaptimmune (Inst); Blueprint Medicines (Inst); Deciphera; Deciphera (Inst); Eisai (Inst); Ellipses Pharma (Inst); Exelixis (Inst); Genmab (Inst); Intellisphere (Inst); Lilly (Inst); Loxo (Inst); Merck (Inst); Plexxikon (Inst); SERVIER (Inst); Transgene (Inst)

Research Funding - CoBioRes NV (Inst); Eisai (Inst); G1 Therapeutics (Inst); Novartis (Inst); PharmaMar (Inst)

Travel, Accommodations, Expenses - Ipsen (Inst); MSD (Inst)

Cesar  Serrano

Honoraria - Bayer

Consulting or Advisory Role - Blueprint Medicines; Deciphera

Speakers' Bureau - Blueprint Medicines

Research Funding - Bayer; Deciphera; Pfizer

Travel, Accommodations, Expenses - Bayer; Lilly; Novartis; Pfizer; PharmaMar

Robin L.  Jones

Consulting or Advisory Role - Adaptimmune; Athenex; Blueprint Medicines; Clinigen Group; Daiichi Sankyo; Deciphera; Eisai; Epizyme; Immune Design; Lilly; Merck; PharmaMar; UpToDate

Research Funding - GlaxoSmithKline; MSD

(OPTIONAL) Uncompensated Relationships - TRACON Pharma

Steven  Attia

Research Funding - AB Science (Inst); Adaptimmune (Inst); Advenchen Laboratories (Inst); Bavarian Nordic (Inst); Bayer (Inst); Blueprint Medicines (Inst); BTG (Inst); CBA Pharma (Inst); CytRx Corporation (Inst); Daiichi Sankyo (Inst); Deciphera (Inst); Desmoid Tumor Research Foundation; Epizyme (Inst); FORMA Therapeutics (Inst); Genmab (Inst); GlaxoSmithKline (Inst); Gradalis (Inst); Immune Design (Inst); Incyte (Inst); Karyopharm Therapeutics (Inst); Lilly (Inst); Merck (Inst); Novartis (Inst); Philogen (Inst); PTC Therapeutics (Inst); SpringWorks Therapeutics (Inst); Takeda (Inst); TRACON Pharma (Inst)

Travel, Accommodations, Expenses - Immune Design

Gina Z.  D'Amato

Consulting or Advisory Role - Blueprint Medicines; Epizyme; Janssen; Lilly

Speakers' Bureau - Janssen Oncology; Lilly

Ping  Chi

Consulting or Advisory Role - Deciphera; Exelixis; Merck (I)

Research Funding - Array BioPharma (Inst); Deciphera (Inst)

Peter  Reichardt

Honoraria - Amgen; Bayer; Lilly; Novartis; Pfizer; PharmaMar

Consulting or Advisory Role - Bayer; Clinigen Group; Deciphera; Lilly; Novartis; Pfizer; PharmaMar; Roche

Research Funding - Novartis (Inst)

Mario E.  Lacouture

Honoraria - ADC Therapeutics; Amgen; Apricity Health; AstraZeneca; azitra; azitra; Deciphera; Galderma; Genentech; Janssen; Johnson & Johnson; Kyowa Hakko Kirin; Loxo; Menlo Therapeutics; NCODA; Novartis; Novocure; OnQuality Pharmaceuticals; QED Therapeutics; Roche/Genentech; Seattle Genetics/Astellas; Teva; Teva

Consulting or Advisory Role - Abbvie; Adgero Biopharmaceuticals; Adjucare; Allergan; Amgen; Amryt Pharma; AstraZeneca; Bayer; Biotechspert; Boehringer Ingelheim; Celldex; Debiopharm Group; Dignitana; E.R. Squibb  Sons, LLC; EMD Serono; Galderma; Genentech; Helsinn Healthcare; Janssen Research & Development; Johnson & Johnson; Legacy Healthcare Services; Legacy Healthcare Services; LEO Pharma; Lindi Skin; Lutris; Manner SAS; Menlo Therapeutics; Merck; Novartis; Novocure; OncoDerm; OnQuality Pharmaceuticals; OurBrainBank; Parexel; Paxman; Pierre Fabre; Roche; Roche; Roche; Roche; Seagen; Takeda/Millennium; Teva

Research Funding - Lutris; Novocure; Paxman; US Biotest; Veloce Pharmaceuticals

Travel, Accommodations, Expenses - AstraZeneca; Deciphera; Kyowa Hakko Kirin; Novocure; Teva

Other Relationship - OncoDerm (I)

(OPTIONAL) Uncompensated Relationships - OncoDerm; OncoDerm

Elva  Cha

Travel, Accommodations, Expenses - Deciphera

Julie Nicole  Meade

Employment - Deciphera

Stock and Other Ownership Interests  - Deciphera

Travel, Accommodations, Expenses - Deciphera

Rodrigo  Ruiz-Soto

Employment - Deciphera

Stock and Other Ownership Interests  - Deciphera; Immunogen

Patents, Royalties, Other Intellectual Property - I am an inventor in 3 patents with Immunogen, I transferred the rights to Immunogen. I have not received (and I will not receive) any royalties; I am an inventor in pending patents at Deciphera. I have transferred the rights to Deciphera, I have not received (and will not receive) any royalties

Jean-Yves  Blay

Leadership - Innate Pharma

Honoraria - AstraZeneca; Bristol-Myers Squibb; MSD; PharmaMar; Roche

Consulting or Advisory Role - Bayer; Blueprint Medicines; Deciphera; Pharmamar; Roche

Research Funding - Bayer (Inst); GlaxoSmithKline (Inst); Novartis (Inst); Pharmamar (Inst); Roche (Inst)

Travel, Accommodations, Expenses - Roche

Margaret  von Mehren

Honoraria - Pfizer

Consulting or Advisory Role - deciphera; Exelixis

Research Funding - ADCO (Inst); Arog (Inst); ArQule; Blueprint Medicines (Inst); Deciphera (Inst); Genmab (Inst); Gradalis (Inst); Lilly (Inst); Novartis (Inst); Springworks Therapeutics (Inst)

Travel, Accommodations, Expenses - Deciphera; Deciphera; NCCN

Other Relationship - NCCN