The following represents disclosure information provided by authors of this abstract. The program committee has reviewed all presenting author disclosure reports, identified potential conflicts of interest, and implemented strategies to manage those areas of conflict, where appropriate. All relationships are considered compensated. Relationships are self-held unless otherwise noted. I = Immediate Family Member, Inst = My Institution
 
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MOUNTAINEER:open-label, phase II study of tucatinib combined with trastuzumab for HER2-positive metastatic colorectal cancer (SGNTUC-017, trial in progress).
 
John H. Strickler
Consulting or Advisory Role - Abbvie; Amgen; Bayer; Chengdu Kanghong Biotech; Genentech/Roche; Mereo Biopharma; Natera (Inst); OncoMed; Pfizer; Proteus Digital Health; Seagen (Inst)
Research Funding - A*STAR (Inst); Abbvie (Inst); Amgen (Inst); AstraZeneca/MedImmune (Inst); Bayer (Inst); Curegenix (Inst); Exelixis (Inst); Gilead Sciences (Inst); Leap Therapeutics (Inst); Macrogenics (Inst); Nektar (Inst); OncoMed (Inst); Roche/Genentech (Inst); Sanofi (Inst); Seagen (Inst)
Travel, Accommodations, Expenses - Seagen
 
Kimmie Ng
Consulting or Advisory Role - Seagen; X-Biotix Therapeutics
Research Funding - Genentech/Roche (Inst); Pharmavite (Inst); Revolution Medicines (Inst)
 
Andrea Cercek
Consulting or Advisory Role - Array Biopharma; Bayer; Proteus Digital Health
Research Funding - Abbvie; Rgenix (Inst); Seagen; Tesaro
 
Christos Fountzilas
Research Funding - Astellas Pharma (Inst); Incyte (Inst); Kinex (Inst); Lilly (Inst); MedImmune (Inst); Merck (Inst); Pfizer (Inst); Puma Biotechnology (Inst); Rafael Pharmaceuticals (Inst); Seagen (Inst)
 
Federico Augusto Sanchez
Consulting or Advisory Role - Via Oncology
 
Joleen M. Hubbard
Consulting or Advisory Role - Bayer (Inst)
Research Funding - Bayer (Inst); Boston Biomedical (Inst); eFFECTOR Therapeutics (Inst); Hutchison MediPharma (Inst); Merck (Inst); Senhwa Biosciences (Inst); Taiho Pharmaceutical (Inst); Treos Bio (Inst)
 
Christina Wu
Consulting or Advisory Role - Array BioPHarma
Research Funding - Boston Biomedical (Inst); Bristol-Myers Squibb (Inst); Lycera (Inst); RAPT Therapeutics (Inst); RAPT Therapeutics (Inst); Seagen (Inst); Symphogen (Inst); Vaccinex (Inst)
Travel, Accommodations, Expenses - Array BioPharma
 
Salvatore Siena
Stock and Other Ownership Interests - Guardant Health; Myriad Genetics
Consulting or Advisory Role - Amgen; Bayer; Bristol-Myers Squibb; CheckmAb; Clovis Oncology; Daiichi Sankyo; Incyte; Merck; Novartis; Roche/Genentech; Seagen
Research Funding - MSD Oncology (Inst)
Patents, Royalties, Other Intellectual Property - Amgen
Travel, Accommodations, Expenses - Amgen; Bayer; Roche
 
Josep Tabernero
Consulting or Advisory Role - Array BioPharma; AstraZeneca; Bayer; BeiGene; Biocartis; Boehringer Ingelheim; Chugai Pharma; Foundation Medicine; Genentech; Genmab; HalioDx; Halozyme; Imugene; Inflection Biosciences; Ipsen; Kura Oncology; Lilly; Menarini; Merck Serono; Merrimack; Merus; Molecular Partners; MSD; Novartis; Peptomyc; Pfizer; Pharmacyclics; ProteoDesign; Rafael Pharmaceuticals; Roche; Roche; Sanofi; Seagen; Seagen; Servier; Symphogen; Taiho Pharmaceutical; VCN Biosciences
 
Eric Van Cutsem
Consulting or Advisory Role - Array BioPharma; AstraZeneca; Bayer; Biocartis; Bristol-Myers Squibb; Celgene; Daiichi Sankyo; GlaxoSmithKline; Halozyme; Incyte; Lilly; Merck KGaA; Merck Sharp & Dohme; Novartis; Pierre Fabre; Roche; SERVIER; Sirtex Medical; Taiho Pharmaceutical
Research Funding - amgen (Inst); Bayer (Inst); Boehringer Ingelheim (Inst); Bristol-Myers Squibb (Inst); Celgene (Inst); Ipsen (Inst); Lilly (Inst); Merck (Inst); Merck KGaA (Inst); Novartis (Inst); Roche (Inst); SERVIER (Inst)
 
Adel Kardosh
Consulting or Advisory Role - Exelixis; Exelixis
 
Anwaar Saeed
Consulting or Advisory Role - AstraZeneca; Bristol-Myers Squibb; Exelixis; Merck Sharp & Dohme; Pfizer
Research Funding - Actuate Therapeutics (Inst); Astellas Pharma (Inst); AstraZeneca/MedImmune (Inst); Bristol-Myers Squibb (Inst); Clovis Oncology (Inst); Exelixis (Inst); Five Prime Therapeutics (Inst); Merck Sharp & Dohme (Inst); Seagen (Inst)
 
Thierry Andre
Honoraria - AMGEN; Bayer; Bristol-Myers Squibb; GlaxoSmithKline; Pierre Fabre; Roche/Genentech; Sanofi; SERVIER; Ventana Medical Systems
Consulting or Advisory Role - Amgen; AstraZeneca/MedImmune; Bayer; Bristol-Myers Squibb; Clovis Oncology; GamaMabs Pharma; Gastrointestinal Cancers Advice; HalioDX; MSD Oncology; Pierre Fabre; SERVIER; Tesaro
Travel, Accommodations, Expenses - Amgen; Bristol-Myers Squibb; Bristol-Myers Squibb; MSD Oncology; MSD Oncology; MSD Oncology; Roche; Roche/Genentech; Ventana Medical Systems
 
Michael Stecher
Employment - Seagen; XBiotech
Leadership - XBiotech
Stock and Other Ownership Interests - Seagen; XBiotech
Travel, Accommodations, Expenses - Seagen
 
Maria Corinna Palanca-Wessels
Employment - Seagen
Stock and Other Ownership Interests - Seagen
 
Tanios S. Bekaii-Saab
Consulting or Advisory Role - Abbvie; Amgen (Inst); Bayer (Inst); Celgene (Inst); Immuneering; Imugene; Incyte (Inst); Ipsen (Inst); Lilly (Inst); Pfizer (Inst); Roche/Genentech (Inst); Seagen (Inst)
Other Relationship - ARMO BioSciences; AstraZeneca; Exelixis; Lilly; Merck (Inst); Sillajen