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Predictive value of plasma tumor mutation burden (TMB) in the CCTG PA.7 trial: Gemcitabine (GEM) and nab-paclitaxel (Nab-P) vs. GEM, nab-P, durvalumab (D) and tremelimumab (T) as first line therapy in metastatic pancreatic ductal adenocarcinoma (mPDAC). |
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Honoraria - Celgene; Ipsen; Roche; SERVIER; Taiho Pharmaceutical |
Consulting or Advisory Role - AstraZeneca; Celgene; SERVIER; Shire; Taiho Pharmaceutical |
Research Funding - AstraZeneca (Inst); Bayer (Inst) |
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Consulting or Advisory Role - AMGEN; Bayer; Eisai; Ipsen; Novartis; Pfizer; Taiho Pharmaceutical |
Research Funding - Ipsen (Inst) |
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Honoraria - Novartis; Roche Canada |
Consulting or Advisory Role - AstraZeneca/MedImmune; Lilly; Merck |
Research Funding - AstraZeneca; Ipsen; Merck |
Expert Testimony - AstraZeneca |
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Stock and Other Ownership Interests - Bristol-Myers Squibb; Teva |
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Consulting or Advisory Role - Amgen; Bristol-Myers Squibb; Eisai; Merck; Novartis; Pfizer; Roche Canada; Taiho Pharmaceutical |
Research Funding - Amgen (Inst) |
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No Relationships to Disclose |
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Honoraria - AstraZeneca; GlaxoSmithKline; Pfizer; Roche Canada |
Consulting or Advisory Role - Amgen; Eisai |
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Consulting or Advisory Role - Bristol-Myers Squibb |
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Leadership - AurKa Pharma; Esperas Pharma; Ocellaris Pharma |
Honoraria - AurKa Pharma; Esperas Pharma; Ocellaris Pharma |
Consulting or Advisory Role - Bayer; Esperas Pharma; Pfizer; Taiho Pharmaceutical |
Travel, Accommodations, Expenses - Taiho Pharmaceutical; Taiho Pharmaceutical |
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No Relationships to Disclose |
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No Relationships to Disclose |
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Consulting or Advisory Role - Amgen; AstraZeneca; Bayer; Bristol-Myers Squibb; Celgene; Ipsen; Merck; Novartis; Pfizer; Roche Canada |
Research Funding - AstraZeneca (Inst); Merck (Inst) |
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No Relationships to Disclose |
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Consulting or Advisory Role - AMGEN; AstraZeneca; AstraZeneca; Celgene; Eisai; Eisai; Genomic Health International; Merck; Pfizer; Pfizer; Taiho Pharmaceutical; Teva |
Travel, Accommodations, Expenses - Amgen |
Other Relationship - Novartis |
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No Relationships to Disclose |
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No Relationships to Disclose |
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Stock and Other Ownership Interests - Satisfai Health |
Honoraria - Alimentiv; Amgen; Diaceutics; Pfizer |
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Consulting or Advisory Role - Amgen; Bristol-Myers Squibb; Eisai; Ipsen; Roche Canada; Taiho Pharmaceutical |
Speakers' Bureau - Amgen; Taiho Pharmaceutical |
Research Funding - Taiho Pharmaceutical (Inst) |
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No Relationships to Disclose |
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Christopher J. O'Callaghan |
No Relationships to Disclose |