The following represents disclosure information provided by authors of this abstract. The program committee has reviewed all presenting author disclosure reports, identified potential conflicts of interest, and implemented strategies to manage those areas of conflict, where appropriate. All relationships are considered compensated. Relationships are self-held unless otherwise noted. I = Immediate Family Member, Inst = My Institution
 
Open Payments is a public database containing information reported by companies about payments made to US-licensed physicians (Open Payments)
 
 
Honoraria - Astellas Pharma
Consulting or Advisory Role - AstraZeneca; Bayer; Blue Earth Diagnostics; Clovis Oncology; Ferring; Hinova Pharmaceuticals; Janssen
Research Funding - Aragon Pharmaceuticals; Astellas Pharma; AstraZeneca; Bayer; Clovis Oncology; eFFECTOR Therapeutics; Emergent BioSolutions; Ferring; Medivation; Pfizer
Travel, Accommodations, Expenses - Bayer; Blue Earth Diagnostics; Clovis Oncology; Ferring; Hinova Pharmaceuticals; Janssen
 
Consulting or Advisory Role - Astellas Pharma; Bristol-Myers Squibb; Genzyme; Janssen-Cilag; MSD Oncology
Research Funding - Astellas Pharma; Genentech/Roche; Janssen-Cilag; Pfizer
Travel, Accommodations, Expenses - Astellas Pharma; Bristol-Myers Squibb; MSD Oncology

TALAPRO-1: Phase II study of talazoparib (TALA) in patients (pts) with DNA damage repair alterations (DDRm) and metastatic castration-resistant prostate cancer (mCRPC).
 
Johann S. De Bono
Employment - Institute of Cancer Research
Honoraria - Amgen; Astellas Pharma; Astex Pharmaceuticals; AstraZeneca; Bayer; BioExcel; Boehringer Ingelheim; Celgene; CellCentric; Daiichi Sankyo; Eisai; Genentech/Roche; Genmab; GlaxoSmithKline; Harpoon; Janssen Oncology; Medivation; Menarini Silicon Biosystems; Merck Serono; Merck Sharp & Dohme; Orion; Pfizer; Qiagen; Sanofi; Sierra Oncology; Taiho Pharmaceutical; Terumo; Vertex
Consulting or Advisory Role - Amgen; Astellas Pharma; Astellas Pharma; AstraZeneca; Bayer; BioXCel therapeutics; Boehringer Ingelheim; CellCentric; Daiichi Sankyo; Eisai; Genentech/Roche; Genmab; GlaxoSmithKline; Harpoon; Janssen Oncology; Menarini Silicon Biosystems; Merck Serono; Merck Sharp & Dohme; Orion; Pfizer; Qiagen; Sanofi; Sanofi Aventis GmbH; Sierra Oncology; Taiho Pharmaceutical; Terumo; Vertex
Research Funding - Amgen; Astellas Pharma; Astex Pharmaceuticals; AstraZeneca; Bayer; CellCentric; Daiichi Sankyo; Genentech/Roche; Genmab; GlaxoSmithKline; Harpoon; Janssen; Menarini Silicon Biosystems; Merck Serono; Merck Sharp & Dohme; Orion; Pfizer; Sanofi; Sanofi Aventis GmbH; Sierra Oncology; Taiho Pharmaceutical; Vertex
Patents, Royalties, Other Intellectual Property - Abiraterone Rewards to Inventors (Inst); CHK1 inhibitor (Inst); PARP inhibitors and DNA repair defects (Inst); Targeting of IL23 in prostate cancer (Inst)
Travel, Accommodations, Expenses - Amgen; Astellas Pharma; AstraZeneca; Bayer; BioXCel therapeutics; Boehringer Ingelheim; Cellcentric; Daiichi Sankyo; Eisai; Genentech/Roche; Genmab; GlaxoSmithKline; Harpoon; Janssen; Menarini Silicon Biosystems; Merck Serono; Merck Sharp & Dohme; Orion; Pfizer; Qiagen; Qiagen; Sanofi; Sierra Oncology; Taiho Pharmaceutical; Terumo; Vertex
 
Niven Mehra
No Relationships to Disclose
 
Celestia S. Higano
No Relationships to Disclose
 
Fred Saad
Honoraria - Abbvie; Amgen; Astellas Pharma; AstraZeneca; Bayer; Janssen
Consulting or Advisory Role - Astellas Pharma; AstraZeneca/MedImmune; Bayer; Janssen
Research Funding - Astellas Pharma; AstraZeneca; Bayer; Bristol-Myers Squibb; Janssen; Pfizer
 
Consuelo Buttigliero
Consulting or Advisory Role - Janssen-Cilag
Speakers' Bureau - ipsen
 
Inge M. van Oort
Consulting or Advisory Role - Astellas Pharma; Bayer; Janssen; Roche; Sanofi
Research Funding - Astellas Pharma (Inst); Bayer (Inst); Janssen (Inst)
 
Marielena Mata
Employment - Pfizer
Stock and Other Ownership Interests - Pfizer
 
Hsiang-Chun Chen
Employment - Pfizer
Stock and Other Ownership Interests - Pfizer
 
Cynthia G. Healy
Employment - Pfizer
Stock and Other Ownership Interests - Pfizer
 
Akos Czibere
Employment - Pfizer
Stock and Other Ownership Interests - Pfizer
 
Karim Fizazi
Honoraria - Astellas Pharma; Bayer; Janssen; Sanofi
Consulting or Advisory Role - Amgen (Inst); Astellas Pharma; AstraZeneca (Inst); Bayer; Curevac; ESSA (Inst); Janssen Oncology (Inst); Orion; Sanofi (Inst)
Travel, Accommodations, Expenses - Janssen; MSD