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Phase I study of AMG 509, a STEAP1 x CD3 T-cell recruiting XmAb 2+1 immune therapy, in patients with metastatic castration-resistant prostate cancer (mCRPC). |
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Honoraria - Bayer; Janssen Oncology |
Consulting or Advisory Role - Merck Sharp & Dohme |
Research Funding - Amgen (Inst); Bayer (Inst); BioClin Therapeutics (Inst); Endocyte (Inst); Exelixis (Inst); Janssen Oncology (Inst); Novartis (Inst); Roche (Inst); Sanofi (Inst); Sarah Cannon Research Institute (Inst); Seagen (Inst) |
Travel, Accommodations, Expenses - Janssen Oncology; Merck Sharp & Dohme |
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Honoraria - Astellas Pharma; Ipsen; Novartis |
Consulting or Advisory Role - Bristol-Myers Squibb; Bristol-Myers Squibb; Merck Sharp & Dohme; Merck Sharp & Dohme (Inst); Pfizer; Pfizer (Inst) |
Research Funding - Amgen (Inst); Astellas Pharma (Inst); Bayer (Inst); Bristol-Myers Squibb (Inst); Exelixis (Inst); Medivation (Inst); Merck Sharp & Dohme (Inst); Pfizer (Inst); Roche (Inst); SymVivo (Inst) |
Travel, Accommodations, Expenses - Amgen; Astellas Pharma; Bristol-Myers Squibb; Pfizer |
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Consulting or Advisory Role - AADi |
Research Funding - Acerta Pharma (Inst); Agensys (Inst); Amgen; Amgen (Inst); Astellas Pharma (Inst); AVEO (Inst); Bayer (Inst); Bristol-Myers Squibb (Inst); Calithera Biosciences (Inst); Eisai (Inst); Exelixis (Inst); Genentech/Roche (Inst); Inovio Pharmaceuticals (Inst); Lilly (Inst); Merck (Inst); Novartis (Inst); Peloton Therapeutics (Inst); Pfizer (Inst); Seagen (Inst); Tokai Pharmaceuticals (Inst) |
Other Relationship - Pfizer |
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Consulting or Advisory Role - Abbvie; Amgen; AZTherapies; Bristol-Myers Squibb; Celgene; CTI; Exelixis; Janssen Oncology; Jazz Pharmaceuticals; McGivney Global Advisors; Seagen |
Speakers' Bureau - Bristol-Myers Squibb; Janssen Oncology |
Travel, Accommodations, Expenses - Bristol-Myers Squibb |
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Employment - Connected Medical Solutions (I) |
Leadership - Connected Medical Solutions (I) |
Stock and Other Ownership Interests - Connected Medical Solutions (I); Imagion Biosystems |
Consulting or Advisory Role - Imagion Biosystems |
Research Funding - Astellas Pharma |
Travel, Accommodations, Expenses - Astellas Pharma; Janssen-Cilag; Pfizer |
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William Jeffery Edenfield |
Consulting or Advisory Role - Chimerix |
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Honoraria - AstraZeneca; Bayer; Chugai Pharma (Inst); Janssen; MSD |
Consulting or Advisory Role - AstraZeneca; Janssen; Lilly; Sanofi |
Research Funding - Astellas Pharma (Inst); AstraZeneca (Inst); Bayer (Inst); Bayer Yakuhin (Inst); Chugai Pharma (Inst); Janssen (Inst); MSD (Inst) |
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Honoraria - Angle; Astellas Pharma; AxImmune; Bayer; Clovis Oncology; Janssen Oncology; Pfizer; Pfizer; ScreenCell |
Consulting or Advisory Role - Angle; Astellas Pharma; AxImmune; Bayer; Clovis Oncology; Janssen Scientific Affairs; Pfizer; Pfizer; Sanador |
Research Funding - Genentech; Janssen Research & Development (Inst); Prostate Cancer Foundation |
Patents, Royalties, Other Intellectual Property - GENE EXPRESSION PROFILE ASSOCIATED WITH PROSTATE CANCER |
Travel, Accommodations, Expenses - American Austrian Open Medical Institute; Astellas Pharma; Cambridge Healthtech Institute; Genzyme; Janssen Biotech; Janssen Scientific Affairs; Pfizer; Prostate Cancer Foundation; ScreenCell; Stop Cancer |
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Honoraria - Clovis Oncology |
Consulting or Advisory Role - AstraZeneca; Dendreon; Janssen |
Research Funding - Abbvie (Inst); Amgen (Inst); Cancer Targeted Technology (Inst); Janssen (Inst); Merck (Inst); Novartis (Inst); Xynomic Pharma (Inst); Zenith Epigenetics (Inst) |
Travel, Accommodations, Expenses - Xynomic Pharma |
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Stock and Other Ownership Interests - Bellicum Pharmaceuticals; TYME |
Consulting or Advisory Role - Advanced Accelerator Applications; Amgen; Astellas Pharma; AstraZeneca; Bayer; Bicycle Therapeutics; Boehringer Ingelheim; Bristol-Myers Squibb; Clovis Oncology; Exelixis; Incyte; Ipsen; Janssen; Janssen; Lilly; Mirati Therapeutics; Monopteros Therapeutics; Pfizer; Pharmacyclics; Roche; Seagen; Urogen pharma |
Research Funding - Advanced Accelerator Applications (Inst); Agensys (Inst); Astellas Medivation (Inst); AstraZeneca (Inst); Bayer (Inst); BioXCel therapeutics (Inst); Bristol-Myers Squibb (Inst); Clovis Oncology (Inst); Eisai (Inst); Endocyte (Inst); Genentech (Inst); Innocrin Pharma (Inst); Lilly (Inst); MedImmune (Inst); Merck (Inst); Mirati Therapeutics (Inst); Novartis (Inst); Pfizer (Inst); Progenics (Inst); Replimune (Inst); Roche (Inst); Sanofi (Inst); Seagen (Inst) |
Expert Testimony - Celgene; sanofi |
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Stock and Other Ownership Interests - Abbvie; Cardinal Health; Clarity Pharmaceuticals; Clovis Oncology; GlaxoSmithKline; Lilly; Noria Therapeutics; PSMA Therapeutics; United Health Group |
Consulting or Advisory Role - Advanced Accelerator Applications; Astellas Pharma; AstraZeneca; Bavarian Nordic; Bayer; Blue Earth Diagnostics; Bristol-Myers Squibb; Clarity Pharmaceuticals; Clovis Oncology; Constellation Pharmaceuticals; Dendreon; EMD Serono; Fusion Pharmaceuticals; Isotopen Technologien; Janssen; Myovant Sciences; Myriad Genetics; Noria Therapeutics; Novartis; Noxopharm; Pfizer; Point Biopharma; Progenics; Sanofi; Telix Pharmaceuticals; TeneoBio; Theragnostics |
Research Funding - Advanced Accelerator Applications (Inst); AstraZeneca (Inst); Bayer (Inst); Constellation Pharmaceuticals (Inst); Dendreon (Inst); Endocyte (Inst); InVitae (Inst); Janssen; Merck (Inst); Progenics; Sanofi (Inst); SOTIO |
Expert Testimony - Sanofi |
Travel, Accommodations, Expenses - AstraZeneca; Bayer; Johnson & Johnson; Progenics; Sanofi |
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No Relationships to Disclose |
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Consulting or Advisory Role - Astellas Pharma |
Research Funding - Genentech (Inst); Merck (Inst) |
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Honoraria - Astellas Scientific and Medical Affairs Inc |
Consulting or Advisory Role - Astellas Scientific and Medical Affairs Inc; AstraZeneca; Bayer; Bristol-Myers Squibb; Clovis Oncology; Clovis Oncology; Dendreon; Merck; Pfizer |
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Research Funding - Astellas Pharma (Inst); AstraZeneca (Inst); Bayer (Inst); BeiGene (Inst); Bristol-Myers Squibb (Inst); Bristol-Myers Squibb (Inst); Constellation Pharmaceuticals (Inst); Dendreon (Inst); Gilead Sciences (Inst); Janssen Oncology (Inst); Merck (Inst); Novartis (Inst); Pfizer (Inst); Roche/Genentech (Inst) |
Patents, Royalties, Other Intellectual Property - Circulating tumor cell novel capture technology (Inst) |
Travel, Accommodations, Expenses - Astellas Scientific and Medical Affairs Inc |
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Stock and Other Ownership Interests - Amgen; Gilead Sciences |
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Stock and Other Ownership Interests - Amgen |
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Stock and Other Ownership Interests - Amgen |
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Consulting or Advisory Role - Abbvie; Advanced Accelerator Applications; Bayer; Bristol-Myers Squibb; Dendreon; Exelixis; Janssen Oncology; Noxopharm; Seagen |
Speakers' Bureau - Exelixis |
Research Funding - Bayer; Pfizer (Inst) |