The following represents disclosure information provided by authors of this abstract. The program committee has reviewed all presenting author disclosure reports, identified potential conflicts of interest, and implemented strategies to manage those areas of conflict, where appropriate. All relationships are considered compensated. Relationships are self-held unless otherwise noted. I = Immediate Family Member, Inst = My Institution
 
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A phase I clinical trial of PSMA-directed/TGFβ-insensitive CAR-T cells in metastatic castration-resistant prostate cancer.
 
Vivek Narayan
Consulting or Advisory Role - AstraZeneca; Janssen Oncology; Merck; Modra Pharmaceuticals; Myovant Sciences; Pfizer/EMD Serono; Regeneron
Research Funding - Bristol-Myers Squibb (Inst); GlaxoSmithKline (Inst); Merck (Inst); Pfizer (Inst)
Travel, Accommodations, Expenses - Merck
 
Julie Barber-Rotenberg
No Relationships to Disclose
 
Joseph Fraietta
No Relationships to Disclose
 
Wei-Ting Hwang
Employment - Janssen (I)
Research Funding - Novartis; Tmunity Therapeutics, Inc.
 
Simon F. Lacey
Consulting or Advisory Role - Gilead Sciences
Research Funding - Novartis (Inst); Tmunity Therapeutics, Inc. (Inst)
Patents, Royalties, Other Intellectual Property - Patents and IP related to CAR-T technology licensed to Novartis (Inst)
 
Gabriela Plesa
No Relationships to Disclose
 
Erica L. Carpenter
No Relationships to Disclose
 
Shannon L. Maude
Consulting or Advisory Role - Kite, a Gilead company; Novartis; WUGEN, Inc.
Research Funding - Novartis
Travel, Accommodations, Expenses - Kite, a Gilead company; Novartis; WUGEN, Inc.
 
Priti Lal
No Relationships to Disclose
 
Neha Vapiwala
Consulting or Advisory Role - Magellan Health
 
Jan J. Melenhorst
Patents, Royalties, Other Intellectual Property - Patent related to the manufacturing of CART cells and biomarkers in CART cell therapy
 
Ronnie Sebro
No Relationships to Disclose
 
Michael Farwell
No Relationships to Disclose
 
Michael Moniak
No Relationships to Disclose
 
Joan Gilmore
No Relationships to Disclose
 
Lester Lledo
No Relationships to Disclose
 
Karen Dengel
No Relationships to Disclose
 
Carl H. June
Stock and Other Ownership Interests - Cabaletta Bio; Carisma Therapeutics; Celldex; Cytosen; Tmunity Therapeutics, Inc.
Honoraria - Johnson & Johnson; Novartis; Pfizer
Consulting or Advisory Role - Cabaletta Bio; Carisma Therapeutics; Celldex; Janssen Oncology; Kiadis Pharma; Viracta Therapeutics; WIRB-Copernicus Group
Research Funding - Novartis; Tmunity Therapeutics, Inc.
Patents, Royalties, Other Intellectual Property - IP licensed to Novartis; Royalties paid to University of Pennsylvania; IP licensed to Tmunity (Inst); Office of Naval Research; IP and patent royalties
 
Naomi B. Haas
Consulting or Advisory Role - Calithera Biosciences; Eisai; Exelixis; Merck Sharp & Dohme; Pfizer
Expert Testimony - Lilly (I)