Differences in the genomic landscape of advanced prostate cancer (aPC) patients (pts) with BRCA1 versus BRCA2 mutations as detected by machine learning analysis of the comprehensive genomic profile (CGP) of cell-free DNA (cfDNA).

Raquel  Reisinger

No Relationships to Disclose

Sergiusz  Wesolowski

No Relationships to Disclose

Umang  Swami

No Relationships to Disclose

Pedro C.  Barata

Consulting or Advisory Role - Bayer; Bristol-Myers Squibb; Caris Life Sciences; Clovis Oncology (Inst); Dendreon (Inst); Eisai; EMD Serono; Pfizer

Research Funding - Blue Earth Diagnostics (Inst)

Edgar Javier  Hernandez

No Relationships to Disclose

Roberto  Nussenzveig

Consulting or Advisory Role - Tempus

Gordon  Lemmon

Stock and Other Ownership Interests  - Backdrop Health

Patents, Royalties, Other Intellectual Property - License fee royalties from Backdrop Health.

(OPTIONAL) Uncompensated Relationships - Backdrop Health

Bennet  Peterson

No Relationships to Disclose

Chuck  Hensel

No Relationships to Disclose

Mehmet Asim  Bilen

Consulting or Advisory Role - Bayer; Bristol-Myers Squibb; Eisai; EMD Serono; Exelixis; Genomic Health; Janssen; Nektar; Pfizer; Sanofi; Seagen

Research Funding - Advanced Accelerator Applications (Inst); AstraZeneca (Inst); Bayer (Inst); Bristol-Myers Squibb (Inst); Exelixis (Inst); Genentech/Roche (Inst); Incyte (Inst); Nektar (Inst); Peleton (Inst); Pfizer (Inst); Seagen (Inst); Tricon Pharmaceuticals (Inst); Xencor (Inst)

Elisabeth I.  Heath

Honoraria - Bayer; Dendreon; Sanofi; Seagen

Consulting or Advisory Role - Agensys; Bayer; Dendreon

Speakers' Bureau - Sanofi

Research Funding - Agensys (Inst); AIQ Solutions (Inst); Astellas Pharma (Inst); AstraZeneca (Inst); AstraZeneca (Inst); Bayer (Inst); Boehringer Ingelheim (Inst); Bristol-Myers Squibb (Inst); Calibr (Inst); Caris Life Sciences (Inst); Celgene (Inst); Celldex (Inst); Champions Oncology (Inst); Corcept Therapeutics (Inst); Curemeta (Inst); Daiichi Sankyo Inc. (Inst); Dendreon (Inst); eFFECTOR Therapeutics (Inst); Eisai (Inst); Esanik (Inst); Five Prime Therapeutics (Inst); Fortis (Inst); Genentech/Roche (Inst); GlaxoSmithKline (Inst); Ignyta (Inst); Infinity Pharmaceuticals (Inst); Inovio Pharmaceuticals (Inst); Janssen Research & Development (Inst); Medivation (Inst); Merck (Inst); Merck Sharp & Dohme (Inst); Millennium (Inst); Mirati Therapeutics (Inst); Modra Pharmaceuticals (Inst); Novartis (Inst); Oncolys BioPharma (Inst); Pellficure (Inst); Peloton Therapeutics (Inst); Pharmacyclics (Inst); Plexxikon (Inst); Seagen (Inst); Synta (Inst); Tokai Pharmaceuticals (Inst); Zenith Epigenetics (Inst); Zenith Epigenetics (Inst)

Travel, Accommodations, Expenses - Agensys; Bayer; Sanofi

Other Relationship - Caris Centers of Excellence

Lakshminarayanan  Nandagopal

Honoraria - AstraZeneca

Philip James  Saylor

(OPTIONAL) Uncompensated Relationships - Bayer (Inst)

Hani M.  Babiker

Consulting or Advisory Role - Celgene; Endocyte

Manish  Kohli

Honoraria - Advanced Accelerator Applications

Travel, Accommodations, Expenses - Celgene

Sumanta K.  Pal

Consulting or Advisory Role - Astellas Pharma; Aveo; Bristol-Myers Squibb; Eisai; Exelixis; Genentech; Ipsen; Myriad Pharmaceuticals; Novartis; Pfizer

Michael B.  Lilly

Speakers' Bureau - Guardant Health

Research Funding - Bavarian Nordic (Inst); Bayer (Inst)

Mark  Yandell

Leadership - Backdrop Health; Fabric Genomics

Stock and Other Ownership Interests  - Backdrop Health; Fabric Genomics; IDbyDNA

Consulting or Advisory Role - Fabric Genomics; IDbyDNA

Patents, Royalties, Other Intellectual Property - Backdrop Health

Travel, Accommodations, Expenses - Fabric Genomics

A. Oliver  Sartor

Stock and Other Ownership Interests  - Abbvie; Cardinal Health; Clarity Pharmaceuticals; Clovis Oncology; GlaxoSmithKline; Lilly; Noria Therapeutics; PSMA Therapeutics; United Health Group

Consulting or Advisory Role - Advanced Accelerator Applications; Astellas Pharma; AstraZeneca; Bavarian Nordic; Bayer; Blue Earth Diagnostics; Bristol-Myers Squibb; Clarity Pharmaceuticals; Clovis Oncology; Constellation Pharmaceuticals; Dendreon; EMD Serono; Fusion Pharmaceuticals; Isotopen Technologien; Janssen; Myovant Sciences; Myriad Genetics; Noria Therapeutics; Novartis; Noxopharm; Pfizer; Point Biopharma; Progenics; Sanofi; Telix Pharmaceuticals; TeneoBio; Theragnostics

Research Funding - Advanced Accelerator Applications (Inst); AstraZeneca (Inst); Bayer (Inst); Constellation Pharmaceuticals (Inst); Dendreon (Inst); Endocyte (Inst); InVitae (Inst); Janssen; Merck (Inst); Progenics; Sanofi (Inst); SOTIO

Expert Testimony - Sanofi

Travel, Accommodations, Expenses - AstraZeneca; Bayer; Johnson & Johnson; Progenics; Sanofi

Neeraj  Agarwal

Consulting or Advisory Role - Astellas Pharma; AstraZeneca; AstraZeneca; Bayer; Bristol-Myers Squibb; Eisai; Exelixis; Foundation Medicine; Foundation One Inc; Janssen Oncology; Lilly; Lilly; Lilly; Medivation/Astellas; Merck; Nektar; Novartis; Pfizer; Pfizer; Pharmacyclics; Seagen

Research Funding - Active Biotech (Inst); Amgen (Inst); AstraZeneca (Inst); Bavarian Nordic (Inst); Bayer (Inst); BN ImmunoTherapeutics (Inst); Bristol-Myers Squibb (Inst); Calithera Biosciences (Inst); Celldex (Inst); Eisai (Inst); Exelixis (Inst); Genentech (Inst); GlaxoSmithKline (Inst); Immunomedics (Inst); Janssen (Inst); Merck (Inst); Newlink Genetics (Inst); Novartis (Inst); Pfizer (Inst); Prometheus (Inst); Rexahn Pharmaceuticals (Inst); Sanofi (Inst); Takeda (Inst); TRACON Pharma (Inst)