The following represents disclosure information provided by authors of this abstract. The program committee has reviewed all presenting author disclosure reports, identified potential conflicts of interest, and implemented strategies to manage those areas of conflict, where appropriate. All relationships are considered compensated. Relationships are self-held unless otherwise noted. I = Immediate Family Member, Inst = My Institution
 
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Trial in progress: Phase 1a/b study of PF-07284890 (brain-penetrant BRAF inhibitor) with/without binimetinib in patients with BRAF V600-mutant solid tumors.
 
Vivek Subbiah
Consulting or Advisory Role - Helsinn Therapeutics; Loxo; MedImmune; QED Therapeutics; R-Pharm
Research Funding - Abbvie (Inst); Agensys (Inst); Alfasigma (Inst); Amgen (Inst); Amgen (Inst); Bayer (Inst); Berg Pharma (Inst); Blueprint Medicines (Inst); Boston Biomedical (Inst); D3 Oncology Solutions (Inst); Exelixis (Inst); Fujifilm (Inst); Genentech/Roche (Inst); GlaxoSmithKline (Inst); Idera (Inst); Incyte (Inst); Inhibrx (Inst); LOXO (Inst); Multivir (Inst); NanoCarrier (Inst); Northwest Biotherapeutics (Inst); Novartis (Inst); Pfizer (Inst); PharmaMar (Inst); Takeda (Inst); Turning Point Therapeutics (Inst); Vegenics (Inst)
Travel, Accommodations, Expenses - Bayer; Helsinn Therapeutics; Novartis; PharmaMar
Other Relationship - Medscape
 
Martin Gutierrez
Stock and Other Ownership Interests - Cota Healthcare
Honoraria - Foundation Medicine; Guardant Health
Consulting or Advisory Role - Eisai
Speakers' Bureau - Bristol-Myers Squibb; Lilly; Merck
Research Funding - Acerta Pharma (Inst); Arcus Biosciences (Inst); Array BioPharma (Inst); Bayer (Inst); Boehringer Ingelheim (Inst); Bristol-Myers Squibb (Inst); Celgene (Inst); Checkpoint Therapeutics (Inst); Compass Therapeutics (Inst); Constellation Pharmaceuticals (Inst); Cyteir (Inst); Eisai (Inst); EMD Serono (Inst); Fate Therapeutics (Inst); GlaxoSmithKline (Inst); GSB Pharma (Inst); Incyte (Inst); Infinity Pharmaceuticals (Inst); Johnson & Johnson (Inst); MedImmune (Inst); Merck (Inst); Moderna Therapeutics (Inst); NextCure (Inst); Pfizer (Inst); Pharmacyclics (Inst); Regeneron (Inst); Roche/Genentech (Inst); Sanofi (Inst); Seagen (Inst); Silenseed (Inst); Synlogic (Inst); Tesaro (Inst); Vedanta Biosciences (Inst)
Travel, Accommodations, Expenses - Guardant Health
 
Carey K. Anders
Honoraria - AstraZeneca; Eisai; Elucida Oncology; Genentech/Roche; Immunomedics; IPSEN; Puma Biotechnology; Seagen
Consulting or Advisory Role - AstraZeneca; Eisai; Elucida Oncology; Genentech/Roche; Immunomedics; Ipsen; Puma Biotechnology; Seagen
Research Funding - G1 Therapeutics (Inst); Lilly (Inst); Merck (Inst); Nektar (Inst); Novartis Pharmaceuticals UK Ltd. (Inst); Pfizer (Inst); Puma Biotechnology (Inst); Seagen (Inst); Tesaro (Inst); Zion Pharma (Inst)
Patents, Royalties, Other Intellectual Property - Jones and Bartlett; Up to Date.com
Travel, Accommodations, Expenses - Eisai
 
George Ansstas
Consulting or Advisory Role - Novartis
Research Funding - Novocure
 
Taofeek K. Owonikoko
Stock and Other Ownership Interests - CAMBIUM MEDICAL TECHNOLOGIES
Consulting or Advisory Role - Abbvie; Amgen; AstraZeneca; Bayer; BerGenBio; Boehringer Ingelheim; Bristol-Myers Squibb; Celgene; Eisai; Eisai; EMD Serono; G1 Therapeutics; Ipsen; Janssen; Jazz Pharmaceuticals; Lilly; MedImmune; Merck; Novartis; PharmaMar; Roche/Genentech; Takeda; Wells Fargo; Xcovery; Zentalis
Speakers' Bureau - Abbvie
Research Funding - Abbvie (Inst); Aeglea Biotherapeutics (Inst); Amgen (Inst); Astellas Pharma (Inst); AstraZeneca/MedImmune (Inst); Bayer (Inst); Boehringer Ingelheim (Inst); Boehringer Ingelheim (Inst); Bristol-Myers Squibb (Inst); Calithera Biosciences (Inst); Corvus Pharmaceuticals; Eisai (Inst); Fujifilm (Inst); G1 Therapeutics (Inst); GlaxoSmithKline (Inst); Incyte (Inst); Ipsen (Inst); Loxo/Lilly (Inst); Merck (Inst); Mersana (Inst); Meryx Pharmaceuticals (Inst); Novartis (Inst); Oncorus (Inst); Pfizer (Inst); Regeneron (Inst); Roche/Genentech (Inst); Turning Point Therapeutics (Inst); United Therapeutics (Inst); WindMIL (Inst)
Patents, Royalties, Other Intellectual Property - DR4 Modulation and its Implications in EGFR-Target Cancer Therapy Ref:18089 PROV (CSP) United States Patent Application No. 62/670,210 June 26, 2018 (Co-Inventor) (Inst); OVERCOMING ACQUIRED RESISTANCE TO CHEMOTHERAPY TREATMENTS THROUGH SUPPRESSION OF STAT3 (Inst); SELECTIVE CHEMOTHERAPY TREATMENTS AND DIAGNOSTIC METHODS RELATED THERETO (Inst); Soluble FAS ligand as a biomarker of recurrence in thyroid cancer; provisional patent 61/727,519 (Inventor) (Inst)
Other Relationship - EMD Serono; Roche/Genentech
(OPTIONAL) Uncompensated Relationships - Reflexion Medical
 
Varun Monga
Consulting or Advisory Role - Forma Therapeutics
Research Funding - Amgen (Inst); ImmunoCellular Therapeutics (Inst); Newlink Genetics (Inst); Orbus Therapeutics (Inst)
Travel, Accommodations, Expenses - Deciphera (Inst); GlaxoSmithKline (Inst)
 
Peter A. J. Forsyth
Honoraria - Abbvie; BTG; Novocure
Consulting or Advisory Role - Abbvie; Boehringer Ingelheim; BTG; Novocure; Tocagen; ZIOPHARM Oncology
Research Funding - Bankhead-Coley Cancer Research; Department of Defense; Florida Academic Cancer Center Alliance; NIH/NCI; Pfizer
Travel, Accommodations, Expenses - Abbvie; Bayer; Bristol-Myers Squibb; BTG; Inovio Pharmaceuticals; National Cancer Research Institute (NCRI); NCI; NIH; Physical Sciences Oncology Network
 
Ibiayi Dagogo-Jack
Honoraria - American Academic Health System; Creative Educational Concepts; Foundation Medicine
Consulting or Advisory Role - AstraZeneca; Boehringer Ingelheim; BostonGene; Catalyst Pharmaceuticals; Novocure; Pfizer; Syros Pharmaceuticals; Xcovery
Research Funding - Array BioPharma (Inst); Bristol-Myers Squibb (Inst); Calithera Biosciences (Inst); Genentech (Inst); Guardant Health (Inst); Novartis (Inst); Pfizer (Inst)
Travel, Accommodations, Expenses - Array BioPharma; Pfizer
 
Sunandana Chandra
Honoraria - Array BioPharma; Bristol Myers Squibb; EMD Serono; Novartis; Pfizer; Sanofi/Regeneron
Consulting or Advisory Role - Array BioPharma; Bristol-Myers Squibb; EMD Serono; Exicure; Novartis; Pfizer; Sanofi/Regeneron
Speakers' Bureau - Array BioPharma; Bristol-Myers Squibb; Pfizer; Sanofi/Regeneron
Other Relationship - Array BioPharma; Bristol-Myers Squibb; EMD Serono; Regeneron
 
Katy K. Tsai
Consulting or Advisory Role - Regeneron
Research Funding - Array BioPharma (Inst); Bristol-Myers Squibb (Inst); Oncosec (Inst); Parker Institute for Cancer Immunotherapy (Inst); Pfizer (Inst); Regeneron (Inst); Replimune (Inst)
Travel, Accommodations, Expenses - Bristol-Myers Squibb
 
Eli L. Diamond
(OPTIONAL) Uncompensated Relationships - Third Rock Ventures
 
Meredith McKean
Consulting or Advisory Role - Array BioPharma (Inst); AstraZeneca (Inst); Pfizer (Inst); Regeneron (Inst)
Research Funding - Ascentage Pharma Group (Inst); Bicycle Therapeutics (Inst); Dragonfly Therapeutics (Inst); Epizyme (Inst); Exelixis (Inst); Genentech (Inst); GlaxoSmithKline (Inst); IDEAYA Biosciences (Inst); Ikena Oncology (Inst); Infinity Pharmaceuticals (Inst); Jacobio (Inst); Moderna Therapeutics (Inst); NBE Therapeutics (Inst); Novartis (Inst); Oncorus (Inst); Plexxikon (Inst); Prelude Therapeutics (Inst); Regeneron (Inst); Sapience Therapeutics (Inst); Seagen (Inst); Tizona Therapeutics, Inc. (Inst); Tmunity Therapeutics, Inc. (Inst); Top Alliance BioScience (Inst)
 
Elizabeth Iannotti Buchbinder
Employment - Alexion Pharmaceuticals (I)
Consulting or Advisory Role - Apexigen; Bristol-Myers Squibb; Novartis; Shionogi
Research Funding - Bristol-Myers Squibb; Checkmate Pharmaceuticals; Genentech/Roche; Lilly; Novartis
 
Dale Nepert
Employment - Pfizer
Stock and Other Ownership Interests - Pfizer
 
Kim Ingram
Employment - Pfizer
Stock and Other Ownership Interests - Pfizer
 
Colleen Oliver
Employment - Pfizer
Stock and Other Ownership Interests - Pfizer
 
Micaela Reddy
Employment - Pfizer
Stock and Other Ownership Interests - Pfizer
 
Kati Maharry
Employment - Array BioPharma; Pfizer
Stock and Other Ownership Interests - Array BioPharma; Pfizer
Travel, Accommodations, Expenses - Array BioPharma; Pfizer
 
Yan Xing
No Relationships to Disclose