The following represents disclosure information provided by authors of this abstract. The program committee has reviewed all presenting author disclosure reports, identified potential conflicts of interest, and implemented strategies to manage those areas of conflict, where appropriate. All relationships are considered compensated. Relationships are self-held unless otherwise noted. I = Immediate Family Member, Inst = My Institution
 
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TALAPRO-2: A phase 3 randomized study of enzalutamide (ENZA) plus talazoparib (TALA) versus placebo in patients with new metastatic castration-resistant prostate cancer (mCRPC).
 
Neeraj Agarwal
Consulting or Advisory Role - Astellas Pharma; Astellas Pharma; AstraZeneca; AstraZeneca; AVEO; Bayer; Bristol-Myers Squibb; Calithera Biosciences; Eisai; EMD Serono; Exelixis; Foundation Medicine; Foundation One Inc; Genentech; Janssen Oncology; Lilly; Lilly; Lilly; Medivation/Astellas; MEI Pharma; Merck; Nektar; Novartis; Pfizer; Pfizer; Pharmacyclics; Seagen
Research Funding - Active Biotech (Inst); Amgen (Inst); AstraZeneca (Inst); Bavarian Nordic (Inst); Bayer (Inst); BN ImmunoTherapeutics (Inst); Bristol-Myers Squibb (Inst); Calithera Biosciences (Inst); Celldex (Inst); Eisai (Inst); Exelixis (Inst); Genentech (Inst); GlaxoSmithKline (Inst); Immunomedics (Inst); Janssen (Inst); Merck (Inst); Newlink Genetics (Inst); Novartis (Inst); Pfizer (Inst); Prometheus (Inst); Rexahn Pharmaceuticals (Inst); Sanofi (Inst); Takeda (Inst); TRACON Pharma (Inst)
 
Arun Azad
Honoraria - Amgen; Astellas Pharma; AstraZeneca; Bayer; Bristol-Myers Squibb; Ipsen; Janssen; Merck Serono; Merck Sharp & Dohme; Novartis; Noxopharm; Pfizer; Sanofi; Telix Pharmaceuticals; Tolmar
Consulting or Advisory Role - Amgen; Astellas Pharma; AstraZeneca; Bayer; Bristol-Myers Squibb; Ipsen; Janssen; Merck Serono; Merck Sharp & Dohme; Novartis; Noxopharm; Pfizer; Sanofi; Telix Pharmaceuticals; Tolmar
Speakers' Bureau - Amgen; Astellas Pharma; Bayer; Bristol-Myers Squibb; Ipsen; Janssen; Merck Serono; Novartis
Research Funding - Aptevo Therapeutics (Inst); Astellas Pharma; Astellas Pharma (Inst); AstraZeneca; AstraZeneca (Inst); Bionomics (Inst); Bristol-Myers Squibb (Inst); GlaxoSmithKline (Inst); Ipsen (Inst); MedImmune (Inst); Merck Serono; Merck Serono (Inst); Novartis (Inst); Pfizer (Inst); Sanofi (Inst); Synthorx (Inst)
Travel, Accommodations, Expenses - Amgen; Astellas Pharma; Janssen; Merck Serono; Pfizer; Sanofi; Tolmar
 
Neal D. Shore
Consulting or Advisory Role - Abbvie; Amgen; Astellas Pharma; AstraZeneca; Bayer; Boston Scientific; Bristol-Myers Squibb/Sanofi; CG Oncology; CG Oncology; Clovis Oncology; Dendreon; Exact Imaging; Exact Sciences; FerGene; Ferring; Foundation Medicine; Genesis Cancer Care; Genzyme; Genzyme; InVitae; Janssen Scientific Affairs; MDxHealth; Medivation/Astellas; Merck; Myovant Sciences; Myriad Genetics; Nymox; Pacific Edge Biotechnology; Pfizer; Phosphorus; Propella Therapeutics; Sanofi; Sesen Bio; Tolmar; Urogen pharma
Speakers' Bureau - Astellas Pharma; AstraZeneca; Bayer; Clovis Oncology; Dendreon; Guardant Health; Janssen; Pfizer
Research Funding - Abbvie; Amgen; Astellas Pharma; AstraZeneca; Bayer; Boston Scientific; Bristol-Myers Squibb/Pfizer; Clovis Oncology; Dendreon; Exact Imaging; Ferring; Foundation Medicine; InVitae; Janssen; MDxHealth; Merck; Myovant Sciences; Myriad Genetics; Nymox; Pfizer; Sanofi; Sesen Bio; Tolmar
 
Joan Carles
Consulting or Advisory Role - Advanced Accelerator Applications/Novartis; Astellas Pharma; AstraZéneca; Bayer; Bristol-Myers Squibb; Johnson & Johnson/Janssen; MSD Oncology; Pfizer; Roche; Sanofi
Speakers' Bureau - Astellas Pharma; Bayer; Johnson & Johnson
Research Funding - AB Science (Inst); Aragon Pharmaceuticals (Inst); Arog (Inst); Astellas Pharma (Inst); AstraZeneca (Inst); AVEO (Inst); Bayer (Inst); Blueprint Medicines (Inst); BN ImmunoTherapeutics (Inst); Boehringer Ingelheim (Inst); Bristol-Myers Squibb International Corporation (BMS) (Inst); Clovis Oncology (Inst); Cougar Biotechnology (Inst); Deciphera; Exelixis (Inst); Genentech (Inst); GlaxoSmithKline (Inst); Incyte (Inst); Janssen-Cilag International NV (Inst); Karyopharm Therapeutics (Inst); Laboratories Leurquin Mediolanum (Inst); Lilly (Inst); Medimmune (Inst); Millenium Pharamceuticals (Inst); Nanobiotix (Inst); Novartis Farmacéutica SA (Inst); Pfizer (Inst); Puma Biotechnology (Inst); Roche (Inst); Sanofi Aventis GmbH (Inst); SFJ Pharmaceuticals Group (Inst); Teva (Inst)
Travel, Accommodations, Expenses - AstraZeneca; BMS; Ipsen; Roche
 
Andre P. Fay
Honoraria - AstraZeneca; Bristol-Myers Squibb; Novartis; Pfizer; Roche
Consulting or Advisory Role - AstraZeneca; Merck Sharp & Dohme; Novartis; Pfizer; Roche
 
Curtis Dunshee
Consulting or Advisory Role - Astellas Pharma; Bayer; Ferring; Genzyme; Pfizer
Research Funding - Astellas Medivation (Inst); AstraZeneca (Inst); Dendreon (Inst); Eleven Biotherapeutics (Inst); Exact Sciences (Inst); Ferring (Inst); GlaxoSmithKline (Inst); Janssen Oncology (Inst); Myovant Sciences (Inst); pfizer (Inst); Siemens (Inst); TesoRX Pharmaceuticals (Inst); Urovant Sciences (Inst)
 
Lawrence Ivan Karsh
Stock and Other Ownership Interests - Swan Valley Medical
Honoraria - Astellas Pharma; AstraZeneca; Bayer; Clovis Oncology; Dendreon; Ferring; Genentech/Roche; Janssen; Merck; Pfizer; UROGPO; Vaxiion
Consulting or Advisory Role - Astellas Pharma; AstraZeneca; Bayer; Clovis Oncology; Dendreon; Ferring; Genentech/Roche; Janssen; Merck; Pfizer; UROGPO; Vaxiion
Speakers' Bureau - Astellas Pharma; AstraZeneca; Bayer; Dendreon; Janssen; Myovant Sciences; Pfizer
Research Funding - Astellas Pharma; AstraZeneca; Bayer; Bristol-Myers Squibb; Dendreon; Epizyme; Exact Sciences; Exelixis; Ferring; FKD Therapies; Genentech/Roche; Hinova Pharmaceuticals; Janssen; Merck; Pfizer; Vaxiion
 
Maria Luisa Paccagnella
Employment - Pfizer
Stock and Other Ownership Interests - Pfizer
 
Nicola Di Santo
Employment - Pfizer
Stock and Other Ownership Interests - Pfizer
 
Mohamed Elmeliegy
Employment - Pfizer
Stock and Other Ownership Interests - Pfizer
 
Xun Lin
Employment - Pfizer
Stock and Other Ownership Interests - Pfizer
 
Alexander Niyazov
Employment - Pfizer
Stock and Other Ownership Interests - Pfizer
 
Akos Czibere
Employment - Pfizer
Stock and Other Ownership Interests - Pfizer
 
Karim Fizazi
Honoraria - Astellas Pharma (Inst); Bayer; Janssen (Inst); Sanofi (Inst)
Consulting or Advisory Role - Amgen (Inst); Astellas Pharma (Inst); AstraZeneca (Inst); Bayer; Bristol-Myers Squibb; Clovis Oncology; Curevac; ESSA (Inst); Janssen Oncology (Inst); Orion; Sanofi (Inst)
Travel, Accommodations, Expenses - Janssen; MSD