The following represents disclosure information provided by authors of this abstract. The program committee has reviewed all presenting author disclosure reports, identified potential conflicts of interest, and implemented strategies to manage those areas of conflict, where appropriate. All relationships are considered compensated. Relationships are self-held unless otherwise noted. I = Immediate Family Member, Inst = My Institution
 
Open Payments is a public database containing information reported by companies about payments made to US-licensed physicians (Open Payments)
Pharmacokinetic (PK) analyses in CSF and plasma from TBCRC049, an ongoing trial to assess the safety and efficacy of the combination of tucatinib, trastuzumab and capecitabine for the treatment of leptomeningeal metastasis (LM) in HER2 positive breast cancer.
 
Erica Michelle Stringer-Reasor
Honoraria - Breast Cancer Index; Lilly; Mylan
Consulting or Advisory Role - Immunomedics; Lilly; Novartis
Speakers' Bureau - Lilly
Research Funding - Susan G. Komen for the Cure; V Foundation
Travel, Accommodations, Expenses - Cascadian Therapeutics; Lilly
(OPTIONAL) Uncompensated Relationships - Genentech
 
Barbara Jane O'Brien
Honoraria - Seagen
 
Ariel Topletz-Erickson
Employment - Seagen
Stock and Other Ownership Interests - Seagen
Patents, Royalties, Other Intellectual Property - “Methods of Treating Breast Cancer with Tucatinib.” (2020). United States Provisional Patent Application No. 62/797,854
 
Jason B White
Patents, Royalties, Other Intellectual Property - Two patents pending at AstraZeneca/Medimmune related to antibody-drug conjugate technology.
 
Mina Lobbous
No Relationships to Disclose
 
Kristen Riley
No Relationships to Disclose
 
Jennifer Childress
No Relationships to Disclose
 
Kim LaMaster
No Relationships to Disclose
 
Michelle E. Melisko
Stock and Other Ownership Interests - Merrimack (I)
Honoraria - Agendia; Genentech (I); Pfizer (I)
Speakers' Bureau - Agendia; Genentech (I); Pfizer (I)
Research Funding - Celldex (Inst); Genentech (Inst); Lilly (Inst); Nektar (Inst); Novartis (Inst); Puma Biotechnology (Inst); Seagen (Inst)
Patents, Royalties, Other Intellectual Property - Multiple patents related to immunoliposomal drugs being studied and potentially brought to market by Merrimack (I)
 
Aki Morikawa
Consulting or Advisory Role - Eisai; Lilly
Research Funding - Eisai (Inst); Eisai (Inst); Eisai (Inst); Genentech/Roche (Inst); Lilly (Inst); Merrimack (Inst); Millenium Pharamceuticals (Inst); Novartis (Inst); Pfizer (Inst); Seagen (Inst); Tempus (Inst)
Other Relationship - Taiho Pharmaceutical
 
John Frederick De Groot
Employment - ZIOPHARM Oncology (I)
Leadership - ZIOPHARM Oncology (I)
Stock and Other Ownership Interests - Gilead Sciences; WuXi Biologics; ZIOPHARM Oncology (I)
Consulting or Advisory Role - Abbvie; Agios; Bioasis Technologies; Cure Brain Cancer Foundation; Debiopharm Group; DelMar Pharmaceuticals; Genentech/Roche; GenomiCare; GlaxoSmithKline; InSightec; Janssen; Karyopharm Therapeutics; KIYATEC; Magnolia Innovation; Merck; Mundipharma Research; Novartis; Prelude Therapeutics; resTORbio; Samus Therapeutics; Sapience Therapeutics; Tocagen; Voyager Therapeutics
Research Funding - CarThera (Inst); Haihe Pharmaceutical (Inst); Taiho Pharmaceutical (Inst)
Other Relationship - VBI Vaccines
 
Ian E. Krop
Employment - AMAG Pharmaceuticals (I); Freeline Therapeutics (I)
Leadership - AMAG Pharmaceuticals (I); Freeline Therapeutics (I)
Stock and Other Ownership Interests - AMAG Pharmaceuticals (I); Freeline Therapeutics (I); vertex (I)
Honoraria - AstraZeneca; Celltrion; Genentech/Roche
Consulting or Advisory Role - AstraZeneca; Bristol-Myers Squibb; Context Therapeutics; Daiichi Sankyo; Genentech/Roche; Ionis Pharmaceuticals; Macrogenics; Merck; Novartis; Seagen; Taiho Pharmaceutical
Research Funding - Genentech (Inst); Pfizer (Inst)
 
Vicente Valero
Honoraria - Genentech/Roche; Merck; Novartis
Consulting or Advisory Role - Genentech/Roche; Merck; Novartis
Travel, Accommodations, Expenses - Genentech/Roche
 
Mothaffar F. Rimawi
Consulting or Advisory Role - Daiichi Sankyo; Genentech; Macrogenics; Seagen
Research Funding - Pfizer (Inst)
 
Antonio C. Wolff
Consulting or Advisory Role - Ionis Pharmaceuticals
Research Funding - Biomarin (Inst); Celldex (Inst)
Patents, Royalties, Other Intellectual Property - Antonio Wolff has been named as inventor on one or more issued patents or pending patent applications relating to methylation in breast cancer, and has assigned his rights to JHU, and participates in a royalty sharing agreement with JHU.
 
Debu Tripathy
Consulting or Advisory Role - AstraZeneca; Genomic Health; GlaxoSmithKline; Novartis; OncoPep; Pfizer
Research Funding - Novartis (Inst); Polyphor (Inst)
Travel, Accommodations, Expenses - AstraZeneca; Novartis
 
Nancy U Lin
No Relationships to Disclose
 
Rashmi Krishna Murthy
Honoraria - AstraZeneca; Genentech; Novartis; Puma Biotechnology; Seagen
Consulting or Advisory Role - AstraZeneca; Genentech/Roche; Novartis; Puma Biotechnology; Seagen
Research Funding - AstraZeneca (Inst); Daiichi Sankyo (Inst); EMD Serono (Inst); Genentech/Roche (Inst); Pfizer (Inst); Seagen (Inst)
Travel, Accommodations, Expenses - Genentech; Seagen