The following represents disclosure information provided by authors of this abstract. The program committee has reviewed all presenting author disclosure reports, identified potential conflicts of interest, and implemented strategies to manage those areas of conflict, where appropriate. All relationships are considered compensated. Relationships are self-held unless otherwise noted. I = Immediate Family Member, Inst = My Institution
 
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Model-based analysis to support dose selection of pevonedistat (PEV) combined with azacitidine (AZA) in patients (pts) with higher-risk myelodysplastic syndromes (MDS)/chronic myelomonocytic leukemia (CMML) and acute myeloid leukemia (AML).
 
Xiaofei Zhou
Employment - Millenium Pharamceuticals
Stock and Other Ownership Interests - Millenium Pharamceuticals
 
Diane R. Mould
Employment - Projections Research
Consulting or Advisory Role - Takeda
Travel, Accommodations, Expenses - Projections Research
 
Dan Zhao
Employment - Millenium Pharamceuticals
 
Mikkael A. Sekeres
Consulting or Advisory Role - Celgene; Millennium; Novartis; Pfizer
Research Funding - Bristol-Myers Squibb (Inst); Pfizer (Inst); Takeda (Inst)
 
Lionel Adès
Honoraria - Abbvie; BerGenBio; Celgene; Jazz Pharmaceuticals; Novartis; Silence Therapeutics
Research Funding - Celgene (Inst)
 
Ronan T. Swords
Stock and Other Ownership Interests - Abbvie
 
Hiroshi Handa
Honoraria - Bristol-Myers Squibb; Celgene; Daiichi Sankyo; Janssen; Kyowa Kirin; Novartis; Ono Pharmaceutical; Sanofi; SymBio Pharmaceuticals; Takeda
Research Funding - Bristol-Myers Squibb; Celgene; Daiichi Sankyo; Janssen; Kyowa Kirin; Novartis; Ono Pharmaceutical; Sanofi; SymBio Pharmaceuticals; Takeda
 
Robert J. Fram
Employment - Takeda
Stock and Other Ownership Interests - Baxter; Bristol-Myers Squibb; Gilead Sciences; Johnson & Johnson; Pfizer; Takeda; Teva
Consulting or Advisory Role - BeyondSpring Pharmaceuticals
Patents, Royalties, Other Intellectual Property - Vertex
Travel, Accommodations, Expenses - Takeda
 
Douglas V. Faller
Employment - Takeda
Stock and Other Ownership Interests - Phoenicia Biosciences; Viracta Therapeutics
Consulting or Advisory Role - Phoenicia Biosciences; Viracta Therapeutics
Patents, Royalties, Other Intellectual Property - Phoenicia Biosciences; Viracta Therapeutics
 
Olga Tsukurov
Employment - Takeda
 
Neeraj Gupta
Employment - Millenium Pharamceuticals
Stock and Other Ownership Interests - Takeda