The following represents disclosure information provided by authors of this abstract. The program committee has reviewed all presenting author disclosure reports, identified potential conflicts of interest, and implemented strategies to manage those areas of conflict, where appropriate. All relationships are considered compensated. Relationships are self-held unless otherwise noted. I = Immediate Family Member, Inst = My Institution
 
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Adrenal-permissive HSD3B1 genetic inheritance and risk of estrogen-driven postmenopausal breast cancer.
 
Nima Sharifi
Consulting or Advisory Role - Celgene
Research Funding - Janssen Oncology
Patents, Royalties, Other Intellectual Property - A patent application has been filed by Cleveland Clinic for a method of steroid-dependent disease treatment based on HSD3B1. Nima Sharifi is a co-inventor on this patent application
 
Megan Lynn Kruse
Consulting or Advisory Role - Eisai; Immunomedics; Lilly; Novartis; Puma Biotechnology; Seagen
Research Funding - Tempus
 
Jeffrey McManus
No Relationships to Disclose
 
Yoon-Mi Chung
No Relationships to Disclose
 
Wei Wei
No Relationships to Disclose
 
Peter Bazeley
No Relationships to Disclose
 
Fumihiko Nakamura
No Relationships to Disclose
 
Aimalie Hardaway
No Relationships to Disclose
 
Erinn Downs Kelley
No Relationships to Disclose
 
Sarat Chandarlapaty
Consulting or Advisory Role - BMS; Lilly; Novartis; Paige.ai; Sanofi; Sermonix Pharmaceuticals; Totus Medicines
Research Funding - Daiichi Sankyo (Inst); Lilly (Inst); Novartis (Inst); Paige.ai (Inst); Sanofi (Inst)
Patents, Royalties, Other Intellectual Property - Patents for (1) targeting mutant ER with ER PROTACS and (2) detecting genomic and histologic alterations in breast cancer using machine learning algorithms. (Inst)
Travel, Accommodations, Expenses - BMS
 
Mathew Thomas
No Relationships to Disclose
 
Halle C. F. Moore
Research Funding - Abbvie (Inst); AstraZeneca (Inst); Daiichi Sankyo (Inst); Puma Biotechnology (Inst); Roche (Inst)
 
George Thomas Budd
Honoraria - Deciphera
Consulting or Advisory Role - Deciphera; Epic Sciences
Speakers' Bureau - Deciphera
Research Funding - Ambrx (Inst); Daiichi Sankyo/Lilly (Inst); Genentech/Roche (Inst); TRACON Pharma (Inst)
 
Wai Hong Wilson Tang
Consulting or Advisory Role - Owkin; Relypsa; Sequana Medical
 
Stanley L. Hazen
Consulting or Advisory Role - Procter & Gamble
Research Funding - Procter & Gamble; Roche
Patents, Royalties, Other Intellectual Property - Cleveland HeartLab
 
Aaron Bernstein
No Relationships to Disclose
 
Serena Nik-Zainal
Consulting or Advisory Role - Artios; AstraZeneca; Scottish Genomes Partnership
Patents, Royalties, Other Intellectual Property - patents on multiple mutational-signature-base algorithms
 
Jame Abraham
Research Funding - Pfizer (Inst); Seagen (Inst)