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A phase 3, randomized, open-label, multicenter, global study of the efficacy and safety of durvalumab (D) + tremelimumab (T) + enfortumab vedotin (EV) or D + EV for neoadjuvant treatment in cisplatin-ineligible muscle-invasive bladder cancer (MIBC) (VOLGA). |
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Consulting or Advisory Role - Astellas Pharma; AstraZeneca; Bristol-Myers Squibb; Eisai; Exelixis; Incyte; Ipsen; Johnson & Johnson; Merck; Merck Serono; MSD; Novartis; Pfizer; Roche; Seagen |
Research Funding - Astellas Pharma; AstraZeneca; Bristol-Myers Squibb; Eisai; Exelixis; Ipsen; Johnson & Johnson; Merck; Merck Serono; MSD; Novartis; Pfizer; Roche; Seagen |
Travel, Accommodations, Expenses - AstraZeneca; Ipsen; MSD; Pfizer; Roche |
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Employment - ATHOS THERAPEUTICS (I); ATTICA SCIENCES (I); Dyania Health (I) |
Leadership - ATHOS THERAPEUTICS (I); ATTICA SCIENCES (I) |
Stock and Other Ownership Interests - Alimera Sciences (I); Athos Therapeutics (I); ATTICA SCIENCES; Dyania Health (I); Kyn therapeutics (I); Moderna Therapeutics (I); PROTEAS BIOANALYTICS (I); Urogen pharma (I) |
Consulting or Advisory Role - AstraZeneca; Bristol-Myers Squibb; DYANIA HEALTH; Exelixis; Janssen; Merck; PACT Pharma; RADMETRIX; Roche/Genentech; Seagen |
Research Funding - AstraZeneca (Inst); BMS (Inst); Genentech/Roche (Inst); Infinity Pharmaceuticals (Inst); Jounce Therapeutics (Inst); Kite/Gilead; Merck Sharp & Dohme (Inst); Seattle Genetics/Astellas (Inst) |
Patents, Royalties, Other Intellectual Property - My significant other has several patents with UCLA, Harvard Medical School, Athos Therapeutics, Proteas Bioanalytics and ATTICA Sciences (I) |
Travel, Accommodations, Expenses - AstraZeneca; Lilly; Seagen |
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Honoraria - Ferring; Janssen |
Consulting or Advisory Role - Ferring; George Clincal; Janssen |
Research Funding - AstraZeneca; Bristol-Myers Squibb |
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Honoraria - Advanced Accelerator Applications; Astellas Pharma; AstraZeneca; Bristol-Myers Squibb; Celgene; Eisai; Eusa Pharma; EUSA Pharma; Genzyme; IPSEN; Janssen-Cilag; Lexicon; Lilly; MSD; Novartis; Pfizer; Pierre Fabre; Roche |
Consulting or Advisory Role - Bristol-Myers Squibb; Ipsen; MSD; Pfizer; Roche; Roche |
Research Funding - Astellas Pharma (Inst); AstraZeneca (Inst); Ipsen (Inst); Lexicon (Inst); Molecular Templates (Inst); Pfizer (Inst); Roche |
Travel, Accommodations, Expenses - Bristol-Myers Squibb; Ipsen; Janssen-Cilag; Pfizer; Roche/Genentech |
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Consulting or Advisory Role - Bristol-Myers Squibb; Daiichi Sankyo Europe GmbH; Novartis; Pfizer; Roche |
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No Relationships to Disclose |
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Honoraria - Abbott Laboratories |
Consulting or Advisory Role - AstraZeneca/MedImmune; Ferring; Janssen; Roche |
Speakers' Bureau - ASCO; AstraZeneca/MedImmune; MSD Oncology; Nucleix; Roche |
Travel, Accommodations, Expenses - European Association of Urology |