The following represents disclosure information provided by authors of this abstract. The program committee has reviewed all presenting author disclosure reports, identified potential conflicts of interest, and implemented strategies to manage those areas of conflict, where appropriate. All relationships are considered compensated. Relationships are self-held unless otherwise noted. I = Immediate Family Member, Inst = My Institution
 
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PROTEUS: A randomized, double-blind, placebo (PBO)-controlled, phase 3 trial of apalutamide (APA) plus androgen deprivation therapy (ADT) versus PBO plus ADT prior to radical prostatectomy (RP) in patients (pts) with localized or locally advanced high-risk prostate cancer (PC).
 
Adam S. Kibel
Honoraria - InSightec; Janssen; Merck; profound
Consulting or Advisory Role - Advantagene; Bristol-Myers Squibb
 
Martin Gleave
Stock and Other Ownership Interests - Sitka; Sustained Therapeutics
Honoraria - Astellas Pharma; AstraZeneca; Bayer; Genova Diagnostics; Janssen; Pfizer; Roche; Sanofi; Tersera
Consulting or Advisory Role - Astellas Pharma; AstraZeneca; Bayer; Genova Diagnostics; Janssen; Pfizer; Roche; Sanofi; Tersera
Research Funding - Astellas Pharma; Bayer; Janssen
Patents, Royalties, Other Intellectual Property - OncoGenex - OGX-011, OGX-427; Sitka - preclinical company focused on novel formulations of taxanes as intravesical agents for superficial bladder cancer; ST-CP; ST-POP
 
Sabine D. Brookman-May
Employment - Janssen Research & Development
Leadership - Janssen Research & Development
Stock and Other Ownership Interests - Johnson & Johnson
 
Won Kim
Employment - Janssen Research & Development
Stock and Other Ownership Interests - Johnson & Johnson
 
Christopher P. Evans
Stock and Other Ownership Interests - Exelixis
Consulting or Advisory Role - Astellas Pharma; Pfizer
Speakers' Bureau - Janssen Biotech; Myovant Sciences; Pfizer
Research Funding - Anchiano (Inst); Astellas Pharma (Inst); Janssen Research & Development (Inst); Pfizer (Inst)
 
Eleni Efstathiou
Honoraria - Astellas Pharma; Janssen-Cilag; Merck; Pfizer; Sanofi; Takeda
Consulting or Advisory Role - AstraZeneca; AstraZeneca; Bayer; Janssen Oncology; Myovant Sciences; Sanofi; Tokai Pharmaceuticals
Research Funding - Janssen-Cilag
 
Philip W. Kantoff
Employment - Convergent Therapeutics
Leadership - Context Therapeutics; Convergent Therapeutics; XLink
Stock and Other Ownership Interests - Cogent Biosciences; Context Therapeutics; Druggablity Technologies; Mirati Therapeutics; Placon; PrognomIQ; Seer; SynDevRx; XLink
Consulting or Advisory Role - Anji Pharma; Candel Therapeutics; Context Therapeutics; Druggablity Technologies; Genentech/Roche; Janssen; Merck; OncoCellMDX; Progenity; PrognomIQ; Seer; SynDevRx; Tarveda Therapeutics; Veru; XLink
Patents, Royalties, Other Intellectual Property - Chromosome Copy Number Gain as a Biomarker of Urothelial Carcinoma Lethality; Composition and Methods for Screening and Diagnosis of Prostate Cancer; Drug Combinations to Treat Cancer; Method for Predicting the Risk of Prostate Cancer Morbidity and Mortality; Methods and Kits for Determining Sensitivity to Cancer Treatment; Methods for Predicting Likelihood of Responding to Treatment; Predicting and Treating Prostate Cancer; Somatic ERCC2 Mutations Correlate with Cisplatin sensitivity in muscle-invasive Urothelial Carcinoma (Patent); Up-to-Date Royalties; Wolters Kluwer Royalties
Other Relationship - Bayer (I)
 
Ashley Ross
Stock and Other Ownership Interests - Decipher Biosciences
Honoraria - Bayer; Blue Earth Diagnostics; Decipher Biosciences; Janssen Biotech; tempus
Consulting or Advisory Role - Astellas Pharma
Speakers' Bureau - Tempus
 
Neal D. Shore
Consulting or Advisory Role - Abbvie; Amgen; Astellas Pharma; AstraZeneca; Bayer; Boston Scientific; Bristol-Myers Squibb/Sanofi; CG Oncology; CG Oncology; Clovis Oncology; Dendreon; Exact Imaging; Exact Sciences; FerGene; Ferring; Foundation Medicine; Genesis Cancer Care; Genzyme; Genzyme; InVitae; Janssen Scientific Affairs; MDxHealth; Medivation/Astellas; Merck; Myovant Sciences; Myriad Genetics; Nymox; Pacific Edge Biotechnology; Peerview; Pfizer; Phosphorus; Propella Therapeutics; Sanofi; Sesen Bio; Speciality Networks; Tolmar; Urogen pharma
Speakers' Bureau - Astellas Pharma; AstraZeneca; Bayer; Clovis Oncology; Dendreon; Foundation Medicine; Guardant Health; Janssen; Merck; Pfizer
Research Funding - Abbvie; Amgen; Astellas Pharma; AstraZeneca; Bayer; Boston Scientific; Bristol-Myers Squibb/Pfizer; Clovis Oncology; Dendreon; Exact Imaging; Ferring; Foundation Medicine; InVitae; Janssen; MDxHealth; Merck; Myovant Sciences; Myriad Genetics; Nymox; Pfizer; Sanofi; Sesen Bio; Tolmar
 
Alberto Briganti
No Relationships to Disclose
 
Boris A. Hadaschik
Consulting or Advisory Role - ABX Advanced biochemical compounds; Amgen; Astellas Pharma; Bayer; Janssen; Lightpoint medical; Merck KGaA; MSD
Research Funding - Janssen
Patents, Royalties, Other Intellectual Property - Uromed
Travel, Accommodations, Expenses - AstraZeneca; BMS; Janssen
 
Axel Heidenreich
Honoraria - Amgen; Astellas Pharma; Bayer; Ferring; Ipsen; Janssen-Cilag; Sanofi; Takeda
Consulting or Advisory Role - Astellas Pharma; AstraZeneca; Bayer; BMS Global; Clovis Oncology; Janssen-Cilag; MSD Oncology
Speakers' Bureau - Amgen; Astellas Pharma; Bayer; Ipsen; Johnson & Johnson; Pfizer; Sanofi; Takeda
Research Funding - Astellas Pharma; Bayer; BMS Oncology; Sanofi
 
Oliver Brendan Rooney
Employment - J&J
Stock and Other Ownership Interests - J&J
 
Shaozhou Ken Tian
Employment - Janssen Research & Development
Stock and Other Ownership Interests - Johnson & Johnson
 
Lisa Wetherhold
Employment - Janssen Research & Development
Stock and Other Ownership Interests - Johnson & Johnson
 
Weichun Xu
Employment - Janssen Research & Development
Stock and Other Ownership Interests - Johnson & Johnson
 
J. Kellogg Parsons
Employment - Janssen Research & Development
Stock and Other Ownership Interests - Johnson & Johnson
 
Kesav Yeruva
Employment - Janssen Research & Development
Stock and Other Ownership Interests - Johnson & Johnson
 
Mary-Ellen Taplin
Honoraria - Abbvie; Amgen; Arcus Biosciences; Astellas Pharma; AstraZeneca; Bayer; Celgene; Clovis Oncology; Constellation Pharmaceuticals; GlaxoSmithKline; Guidepoint Global; Incyte; Janssen-Ortho; Merck; Myovant Sciences; Pfizer; Pfizer; Progenics; Research to Practice; Roivant; UpToDate
Consulting or Advisory Role - Arcus Ventures (I); AstraZeneca; Bayer; Best Doctors, Inc; Clovis Oncology; Guidepoint Global; Incyte; Janssen-Ortho; Myovant Sciences; Pfizer; Research to Practice; UpToDate
Research Funding - Bayer (Inst); Janssen-Ortho (Inst); Medivation (Inst); Pfizer (Inst)
Travel, Accommodations, Expenses - Astellas Pharma; Bayer; Clovis Oncology; Incyte; Janssen Oncology; Medivation; Pfizer; Tokai Pharmaceuticals